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John Fryer
John Fryer
Professor, Associate Dean, Mayo Clinic
Verified email at mayo.edu
Title
Cited by
Cited by
Year
TIA1 mutations in amyotrophic lateral sclerosis and frontotemporal dementia promote phase separation and alter stress granule dynamics
IR Mackenzie, AM Nicholson, M Sarkar, J Messing, MD Purice, C Pottier, ...
Neuron 95 (4), 808-816. e9, 2017
5582017
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE
SE Wahrle, H Jiang, M Parsadanian, J Legleiter, X Han, JD Fryer, ...
Journal of Biological Chemistry 279 (39), 40987-40993, 2004
5282004
Apolipoprotein E is a ligand for triggering receptor expressed on myeloid cells 2 (TREM2)
Y Atagi, CC Liu, MM Painter, XF Chen, C Verbeeck, H Zheng, X Li, ...
Journal of Biological Chemistry 290 (43), 26043-26050, 2015
4772015
C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits
J Chew, TF Gendron, M Prudencio, H Sasaguri, YJ Zhang, ...
Science 348 (6239), 1151-1154, 2015
4512015
Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition
SS Kang, PR Jeraldo, A Kurti, MEB Miller, MD Cook, K Whitlock, ...
Molecular neurodegeneration 9, 1-12, 2014
3552014
Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine
JD Fryer, RJ Lukas
Journal of Pharmacology and Experimental Therapeutics 288 (1), 88-92, 1999
3511999
ATAXIN-1 interacts with the repressor Capicua in its native complex to cause SCA1 neuropathology
YC Lam, AB Bowman, P Jafar-Nejad, J Lim, R Richman, JD Fryer, ...
Cell 127 (7), 1335-1347, 2006
3502006
C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins
YJ Zhang, TF Gendron, JC Grima, H Sasaguri, K Jansen-West, YF Xu, ...
Nature neuroscience 19 (5), 668-677, 2016
3172016
Human apolipoprotein E4 alters the amyloid-β 40: 42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model
JD Fryer, K Simmons, M Parsadanian, KR Bales, SM Paul, PM Sullivan, ...
Journal of Neuroscience 25 (11), 2803-2810, 2005
3162005
Soluble TREM2 induces inflammatory responses and enhances microglial survival
L Zhong, XF Chen, T Wang, Z Wang, C Liao, Z Wang, R Huang, D Wang, ...
Journal of Experimental Medicine 214 (3), 597-607, 2017
2862017
TREM2 promotes microglial survival by activating Wnt/β-catenin pathway
H Zheng, L Jia, CC Liu, Z Rong, L Zhong, L Yang, XF Chen, JD Fryer, ...
Journal of Neuroscience 37 (7), 1772-1784, 2017
2812017
Voluntary and forced exercise differentially alters the gut microbiome in C57BL/6J mice
JM Allen, MEB Miller, BD Pence, K Whitlock, V Nehra, HR Gaskins, ...
Journal of applied physiology, 2015
2772015
Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis
YJ Zhang, TF Gendron, MTW Ebbert, AD O’Raw, M Yue, K Jansen-West, ...
Nature medicine 24 (8), 1136-1142, 2018
2702018
Large-scale topology and the default mode network in the mouse connectome
JM Stafford, BR Jarrett, O Miranda-Dominguez, BD Mills, N Cain, ...
Proceedings of the National Academy of Sciences 111 (52), 18745-18750, 2014
2622014
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice
M Yue, KM Hinkle, P Davies, E Trushina, FC Fiesel, TA Christenson, ...
Neurobiology of disease 78, 172-195, 2015
2502015
Clusterin contributes to caspase-3–independent brain injury following neonatal hypoxia-ischemia
BH Han, RB DeMattos, LL Dugan, JS Kim-Han, RP Brendza, JD Fryer, ...
Nature medicine 7 (3), 338-343, 2001
2472001
Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice
RB DeMattos, RP Brendza, JE Heuser, M Kierson, JR Cirrito, J Fryer, ...
Neurochemistry international 39 (5-6), 415-425, 2001
2252001
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis
TF Gendron, J Chew, JN Stankowski, LR Hayes, YJ Zhang, M Prudencio, ...
Science translational medicine 9 (383), eaai7866, 2017
2232017
A partial loss of function allele of Methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome
RC Samaco, JD Fryer, J Ren, S Fyffe, HT Chao, Y Sun, JJ Greer, ...
Human molecular genetics 17 (12), 1718-1727, 2008
2132008
Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity
YJ Zhang, L Guo, PK Gonzales, TF Gendron, Y Wu, K Jansen-West, ...
Science 363 (6428), eaav2606, 2019
2052019
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