| Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription Y Chen, K Zhou, R Wang, Y Liu, YD Kwak, T Ma, RC Thompson, Y Zhao, ... Proceedings of the National Academy of Sciences 106 (10), 3907-3912, 2009 | 468 | 2009 |
| Metabolic stress modulates Alzheimer’s β-secretase gene transcription via SIRT1-PPARγ-PGC-1 in neurons R Wang, JJ Li, S Diao, YD Kwak, L Liu, L Zhi, H Büeler, NR Bhat, ... Cell metabolism 17 (5), 685-694, 2013 | 215 | 2013 |
| NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration YD Kwak, T Ma, S Diao, X Zhang, Y Chen, J Hsu, SA Lipton, E Masliah, ... Molecular neurodegeneration 5, 1-12, 2010 | 164 | 2010 |
| Amyloid precursor protein regulates differentiation of human neural stem cells YD Kwak, CL Brannen, T Qu, HM Kim, X Dong, P Soba, A Majumdar, ... Stem cells and development 15 (3), 381-389, 2006 | 147 | 2006 |
| Differential regulation of BACE1 expression by oxidative and nitrosative signals YD Kwak, R Wang, JJ Li, YW Zhang, H Xu, FF Liao Molecular neurodegeneration 6, 1-10, 2011 | 105 | 2011 |
| Upregulation of the E3 ligase NEDD4-1 by oxidative stress degrades IGF-1 receptor protein in neurodegeneration YD Kwak, B Wang, JJ Li, R Wang, Q Deng, S Diao, Y Chen, R Xu, ... Journal of Neuroscience 32 (32), 10971-10981, 2012 | 91 | 2012 |
| The Hippo pathway prevents YAP/TAZ-driven hypertranscription and controls neural progenitor number A Lavado, JY Park, J Pare, D Finkelstein, H Pan, B Xu, Y Fan, RP Kumar, ... Developmental cell 47 (5), 576-591. e8, 2018 | 87 | 2018 |
| Stem cell strategies for Alzheimer's disease therapy. K Sugaya, A Alvarez, A Marutle, YD Kwak, E Choumkina Panminerva medica 48 (2), 87-96, 2006 | 79 | 2006 |
| Cell Surface Display of Human Immunodeficiency Virus Type 1 gp120 on Escherichia coli by Using Ice Nucleation Protein YD Kwak, SK Yoo, EJ Kim Clinical Diagnostic Laboratory Immunology 6 (4), 499-503, 1999 | 74 | 1999 |
| Statin's excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling T Ma, YB Zhao, YD Kwak, Z Yang, R Thompson, Z Luo, H Xu, FF Liao Journal of Neuroscience 29 (36), 11226-11236, 2009 | 67 | 2009 |
| Practical issues in stem cell therapy for Alzheimer's disease K Sugaya, YD Kwak, O Ohmitsu, A Marutle, NH Greig, E Choumrina Current Alzheimer Research 4 (4), 370-377, 2007 | 62 | 2007 |
| Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc YD Kwak, B Wang, W Pan, H Xu, X Jiang, FF Liao Journal of biological chemistry 285 (13), 9847-9857, 2010 | 60 | 2010 |
| RNA interference with small hairpin RNAs transcribed from a human U6 promoter-driven DNA vector YD Kwak, H Koike, K Sugaya Journal of pharmacological sciences 93 (2), 214-217, 2003 | 41 | 2003 |
| Secreted type of amyloid precursor protein induces glial differentiation by stimulating the BMP/Smad signaling pathway YD Kwak, BJ Hendrix, K Sugaya Biochemical and Biophysical Research Communications 447 (3), 394-399, 2014 | 35 | 2014 |
| Amyloid-β precursor protein induces glial differentiation of neural progenitor cells by activation of the IL-6/gp130 signaling pathway YD Kwak, E Dantuma, S Merchant, S Bushnev, K Sugaya Neurotoxicity research 18, 328-338, 2010 | 33 | 2010 |
| Human zinc finger protein 161, a novel transcriptional activator of the dopamine transporter KH Lee, YD Kwak, DH Kim, MY Chang, YS Lee, YS Lee Biochemical and biophysical research communications 313 (4), 969-976, 2004 | 30 | 2004 |
| Involvement of notch signaling pathway in amyloid precursor protein induced glial differentiation YD Kwak, A Marutle, E Dantuma, S Merchant, S Bushnev, K Sugaya European journal of pharmacology 650 (1), 18-27, 2011 | 29 | 2011 |
| Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells YD Kwak, E Choumkina, K Sugaya Biochemical and biophysical research communications 344 (1), 431-437, 2006 | 27 | 2006 |
| Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors LC Dumitrache, M Shimada, SM Downing, YD Kwak, Y Li, JL Illuzzi, ... Proceedings of the National Academy of Sciences 115 (52), E12285-E12294, 2018 | 26 | 2018 |
| Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair SM Downing, PA Schreiner, YD Kwak, Y Li, TI Shaw, HR Russell, ... Neuron 109 (24), 3962-3979. e6, 2021 | 25 | 2021 |
Kiminobu SugayaUniversity of Central FloridaVerified email at ucf.edu
