Solving a Levinthal's paradox for virus assembly identifies a unique antiviral strategy EC Dykeman, PG Stockley, R Twarock Proceedings of the National Academy of Sciences 111 (14), 5361-5366, 2014 | 117 | 2014 |
Normal mode analysis and applications in biological physics EC Dykeman, OF Sankey Journal of Physics: Condensed Matter 22 (42), 423202, 2010 | 113 | 2010 |
Packaging signals in single-stranded RNA viruses: nature’s alternative to a purely electrostatic assembly mechanism PG Stockley, R Twarock, SE Bakker, AM Barker, A Borodavka, ... Journal of biological physics 39, 277-287, 2013 | 110 | 2013 |
Direct Evidence for Packaging Signal-Mediated Assembly of Bacteriophage MS2 Ó Rolfsson, S Middleton, IW Manfield, SJ White, B Fan, R Vaughan, ... Journal of molecular biology 428 (2), 431-448, 2016 | 100 | 2016 |
Packaging signals in two single-stranded RNA viruses imply a conserved assembly mechanism and geometry of the packaged genome EC Dykeman, PG Stockley, R Twarock Journal of molecular biology 425 (17), 3235-3249, 2013 | 93 | 2013 |
HBV RNA pre-genome encodes specific motifs that mediate interactions with the viral core protein that promote nucleocapsid assembly. N Patel, SJ White, RF Thompson, R Bingham, EU Weiß, DP Maskell, ... Nature microbiology 2, 17098, 2017 | 85 | 2017 |
Revealing the density of encoded functions in a viral RNA N Patel, EC Dykeman, RHA Coutts, GP Lomonossoff, DJ Rowlands, ... Proceedings of the National Academy of Sciences 112 (7), 2227-2232, 2015 | 77 | 2015 |
Degenerate RNA packaging signals in the genome of satellite tobacco necrosis virus: implications for the assembly of a T= 1 capsid DHJ Bunka, SW Lane, CL Lane, EC Dykeman, RJ Ford, AM Barker, ... Journal of molecular biology 413 (1), 51-65, 2011 | 77 | 2011 |
Genomic RNA folding mediates assembly of human parechovirus S Shakeel, EC Dykeman, SJ White, A Ora, JJB Cockburn, SJ Butcher, ... Nature communications 8 (1), 1-11, 2017 | 76 | 2017 |
Protein-mediated RNA folding governs sequence-specific interactions between rotavirus genome segments A Borodavka, EC Dykeman, W Schrimpf, DC Lamb Elife 6, e27453, 2017 | 75 | 2017 |
The impact of viral RNA on assembly pathway selection VL Morton, EC Dykeman, NJ Stonehouse, AE Ashcroft, R Twarock, ... Journal of molecular biology 401 (2), 298-308, 2010 | 74 | 2010 |
Structural basis for DNA recognition and loading into a viral packaging motor CR Büttner, M Chechik, M Ortiz-Lombardía, C Smits, IO Ebong, V Chechik, ... Proceedings of the National Academy of Sciences 109 (3), 811-816, 2012 | 69 | 2012 |
Dynamic allostery controls coat protein conformer switching during MS2 phage assembly EC Dykeman, PG Stockley, R Twarock Journal of molecular biology 395 (5), 916-923, 2010 | 69 | 2010 |
Low frequency mechanical modes of viral capsids: an atomistic approach EC Dykeman, OF Sankey Physical review letters 100 (2), 028101, 2008 | 68 | 2008 |
Simple rules for efficient assembly predict the layout of a packaged viral RNA EC Dykeman, NE Grayson, K Toropova, NA Ranson, PG Stockley, ... Journal of molecular biology 408 (3), 399-407, 2011 | 67 | 2011 |
A modelling paradigm for RNA virus assembly R Twarock, RJ Bingham, EC Dykeman, PG Stockley Current opinion in virology 31, 74-81, 2018 | 65 | 2018 |
Building a viral capsid in the presence of genomic RNA EC Dykeman, PG Stockley, R Twarock Physical Review E 87 (2), 022717, 2013 | 59 | 2013 |
Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T= 7 capsids OW Bayfield, E Klimuk, DC Winkler, EL Hesketh, M Chechik, N Cheng, ... Proceedings of the National Academy of Sciences 116 (9), 3556-3561, 2019 | 55 | 2019 |
Bacteriophage MS2 genomic RNA encodes an assembly instruction manual for its capsid PG Stockley, SJ White, E Dykeman, I Manfield, O Rolfsson, N Patel, ... Bacteriophage 6 (1), e1157666, 2016 | 52 | 2016 |
Identification of novel RNA secondary structures within the hepatitis C virus genome reveals a cooperative involvement in genome packaging H Stewart, RJ Bingham, SJ White, EC Dykeman, C Zothner, AK Tuplin, ... Scientific reports 6 (1), 1-12, 2016 | 50 | 2016 |