Follow
William Bourguet
William Bourguet
Team leader, Center for Structural Biology
Verified email at cbs.cnrs.fr - Homepage
Title
Cited by
Cited by
Year
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α
W Bourguet, M Ruff, P Chambon, H Gronemeyer, D Moras
Nature 375 (6530), 377-382, 1995
15241995
A canonical structure for the ligand-binding domain of nuclear receptors
JM Wurtz, W Bourguet, JP Renaud, V Vivat, P Chambon, D Moras, ...
Nature structural biology 3 (1), 87-94, 1996
12111996
Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications
W Bourguet, P Germain, H Gronemeyer
Trends in pharmacological sciences 21 (10), 381-388, 2000
6462000
Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains
W Bourguet, V Vivat, JM Wurtz, P Chambon, H Gronemeyer, D Moras
Molecular cell 5 (2), 289-298, 2000
4872000
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers
M de Saint-Jean, V Delfosse, D Douguet, G Chicanne, B Payrastre, ...
Journal of Cell Biology 195 (6), 965-978, 2011
3902011
Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes
V Delfosse, M Grimaldi, JL Pons, A Boulahtouf, A Le Maire, V Cavailles, ...
Proceedings of the National Academy of Sciences 109 (37), 14930-14935, 2012
3772012
Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3
H Greschik, JM Wurtz, S Sanglier, W Bourguet, A van Dorsselaer, ...
Molecular cell 9 (2), 303-313, 2002
3412002
Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate
J Moser von Filseck, A Čopič, V Delfosse, S Vanni, CL Jackson, ...
Science 349 (6246), 432-436, 2015
3372015
Design of selective nuclear receptor modulators: RAR and RXR as a case study
AR de Lera, W Bourguet, L Altucci, H Gronemeyer
Nature reviews Drug discovery 6 (10), 811-820, 2007
3172007
Peroxisome proliferator-activated receptor γ is a target for halogenated analogs of bisphenol A
A Riu, M Grimaldi, A Le Maire, G Bey, K Phillips, A Boulahtouf, E Perdu, ...
Environmental health perspectives 119 (9), 1227-1232, 2011
3132011
Activation of RXR–PPAR heterodimers by organotin environmental endocrine disruptors
A Le Maire, M Grimaldi, D Roecklin, S Dagnino, V Vivat‐Hannah, ...
EMBO reports 10 (4), 367-373, 2009
2862009
Exploring hydrophobic sites in proteins with xenon or krypton
T Prangé, M Schiltz, L Pernot, N Colloc'h, S Longhi, W Bourguet, ...
Proteins: Structure, Function, and Bioinformatics 30 (1), 61-73, 1998
2261998
Modulation of RXR function through ligand design
E Pérez, W Bourguet, H Gronemeyer, AR de Lera
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2012
1922012
A unique secondary-structure switch controls constitutive gene repression by retinoic acid receptor
A Le Maire, C Teyssier, C Erb, M Grimaldi, S Alvarez, AR De Lera, ...
Nature structural & molecular biology 17 (7), 801-807, 2010
1662010
Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds
V Delfosse, B Dendele, T Huet, M Grimaldi, A Boulahtouf, ...
Nature communications 6 (1), 8089, 2015
1602015
Modulators of the structural dynamics of the retinoid X receptor to reveal receptor function
V Nahoum, E Pérez, P Germain, F Rodrı́guez-Barrios, F Manzo, ...
Proceedings of the National Academy of Sciences 104 (44), 17323-17328, 2007
1572007
Estrogen‐related receptor γ is an in vivo receptor of bisphenol A
M Tohmé, SM Prud'homme, A Boulahtouf, E Samarut, F Brunet, L Bernard, ...
The FASEB Journal 28 (7), 3124-3133, 2014
1532014
A mutation mimicking ligand‐induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers
V Vivat, C Zechel, JM Wurtz, W Bourguet, H Kagechika, H Umemiya, ...
The EMBO Journal, 1997
1521997
Characterization of novel ligands of ERα, Erβ, and PPARγ: the case of halogenated bisphenol A and their conjugated metabolites
A Riu, A Le Maire, M Grimaldi, M Audebert, A Hillenweck, W Bourguet, ...
Toxicological Sciences 122 (2), 372-382, 2011
1512011
Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and …
V Pogenberg, JF Guichou, V Vivat-Hannah, S Kammerer, E Pérez, ...
Journal of Biological Chemistry 280 (2), 1625-1633, 2005
1482005
The system can't perform the operation now. Try again later.
Articles 1–20