The 1, 2, 3-triazole ‘all-in-one’ring system in drug discovery: a good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool D Lengerli, K Ibis, Y Nural, E Banoglu Expert Opinion on Drug Discovery 17 (11), 1209-1236, 2022 | 36 | 2022 |
A highly potent TACC3 inhibitor as a novel anticancer drug candidate O Akbulut, D Lengerli, O Saatci, E Duman, UOS Seker, A Isik, A Akyol, ... Molecular cancer therapeutics 19 (6), 1243-1254, 2020 | 27 | 2020 |
Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification O Saatci, O Akbulut, M Cetin, V Sikirzhytski, M Uner, D Lengerli, ... Cell Death & Differentiation, 1-15, 2023 | 13 | 2023 |
Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with In Vitro Growth Inhibitory and In Vivo Antitumor Activity S Turanlı, E Nalbat, D Lengerli, K İbiş, S Güntekin Ergün, ... ACS omega 7 (41), 36206-36226, 2022 | 3 | 2022 |
Crystal structure and Hirshfeld surface analysis of 4-(4-chlorophenyl)-5-methyl-3-{4-[(2-methylphenyl) methoxy] phenyl}-1, 2-oxazole A Aydin, M Akkurt, S Turanli, D Lengerli, E Banoglu, ND Ozcelik Acta Crystallographica Section E: Crystallographic Communications 77 (4 …, 2021 | 3 | 2021 |
Highly potent tacc3 inhibitor as a novel anticancer drug candidate E Banoglu, B Caliskan, O Sahin, D Lengerli, O Akbulut US Patent App. 17/058,982, 2021 | 1 | 2021 |
STUDIES ON THE SYNTHESIS AND ANTICANCER POTENTIAL OF NOVEL 2, 4-DIAMINOPYRIMIDINE DERIVATIVES D LENGERLİ, Ö AKBULUT ÇALIŞKAN, B ÇALIŞKAN, Ö ŞAHİN, ... | 1 | |
Isoxazole derivatives targeting tacc3 as anticancer agents E Banoglu, B Caliskan, O Sahin, D Lengerli, O Akbulut, LIM Chaemin, ... US Patent App. 17/776,767, 2023 | | 2023 |
A novel TACC3 inhibitor as an anti-cancer agent in breast cancer O Akbulut, D Lengerli, O Saatci, E Duman, U Seker, B Caliskan, ... Cancer Research 79 (13 Supplement), 3871-3871, 2019 | | 2019 |
A Novel TACC3 inhibitor as an anti-cancer agent in breast cancer O Akbulut, D Lengerli, B Caliskan, E Banoglu, O Sahin EUROPEAN JOURNAL OF CANCER 103, E71-E71, 2018 | | 2018 |
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL IMIDAZOLIDINONE-THIAZOLE AMIDE HYBRIDS AS INHIBITORS OF HUMAN SOLUBLE EPOXIDE HYDROLASE K İbiş, D Lengerli, P Jordan, B Çalışkan, O Werz, E Banoğlu | | |
Synthesis of New Vicinal Diaryl Five-Membered Heterocyclic Compounds with Potential Anticancer Activity S TURANLİ, D LENGERLİ, B ÇALIŞKAN, ECE AKHAN GÜZELCAN, ... | | |
Synthesis of 3, 4-Diaryl-5-methylisoxazoles with Potent Antiproliferative Activity Against a Panel of Human Liver and Breast Cancer Cell Lines D LENGERLİ, S TURANLİ, B ÇALIŞKAN, ECE AKHAN GÜZELCAN, ... | | |
A SMALL MOLECULE INHIBITOR OF TRANSFORMING ACIDICCOILED-COIL PROTEIN 3 (TACC3): A NOVEL THERAPEUTICSTRATEGY FOR THE TREATMENT OF BREAST CANCER D LENGERLİ, O Akbulut, B ÇALIŞKAN, Ö ŞAHİN, E BANOĞLU | | |