Synthesis and evaluation of new pyrazoline derivatives as potential anticancer agents M Karabacak, MD Altıntop, Hİ Çiftçi, R Koga, M Otsuka, M Fujita, ... Molecules 20 (10), 19066-19084, 2015 | 106 | 2015 |
Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors B Sever, MD Altıntop, MO Radwan, A Özdemir, M Otsuka, M Fujita, ... European journal of medicinal chemistry 182, 111648, 2019 | 89 | 2019 |
Design, synthesis, and biological evaluation of novel 1, 3, 4-thiadiazole derivatives as potential antitumor agents against chronic myelogenous leukemia: Striking effect of … MD Altıntop, HI Ciftci, MO Radwan, B Sever, ZA Kaplancıklı, TFS Ali, ... Molecules 23 (1), 59, 2017 | 77 | 2017 |
A clue to unprecedented strategy to HIV eradication:“Lock-in and apoptosis” H Tateishi, K Monde, K Anraku, R Koga, Y Hayashi, HI Ciftci, H DeMirci, ... Scientific Reports 7 (1), 8957, 2017 | 61 | 2017 |
Comprehensive research on past and future therapeutic strategies devoted to treatment of amyotrophic lateral sclerosis B Sever, H Ciftci, H DeMirci, H Sever, F Ocak, B Yulug, H Tateishi, ... International journal of molecular sciences 23 (5), 2400, 2022 | 56 | 2022 |
Selenium single-wavelength anomalous diffraction de novo phasing using an X-ray-free electron laser MS Hunter, CH Yoon, H DeMirci, RG Sierra, EH Dao, R Ahmadi, F Aksit, ... Nature communications 7 (1), 13388, 2016 | 50 | 2016 |
The first pentacyclic triterpenoid gypsogenin derivative exhibiting anti-ABL1 kinase and anti-chronic myelogenous leukemia activities HI Ciftci, SE Ozturk, TFS Ali, MO Radwan, H Tateishi, R Koga, Z Ocak, ... Biological and Pharmaceutical Bulletin 41 (4), 570-574, 2018 | 44 | 2018 |
In vitro and in silico evaluation of anticancer activity of new indole-based 1, 3, 4-oxadiazoles as EGFR and COX-2 inhibitors B Sever, MD Altıntop, A Özdemir, G Akalın Çiftçi, DE Ellakwa, H Tateishi, ... Molecules 25 (21), 5190, 2020 | 38 | 2020 |
Design, synthesis, and biological activity of Plastoquinone analogs as a new class of anticancer agents N Bayrak, H Yıldırım, M Yıldız, MO Radwan, M Otsuka, M Fujita, AF Tuyun, ... Bioorganic chemistry 92, 103255, 2019 | 37 | 2019 |
Synthesis, computational study, and evaluation of in vitro antimicrobial, antibiofilm, and anticancer activities of new sulfanyl aminonaphthoquinone derivatives N Bayrak, H Yıldırım, A Fatih Tuyun, E Mataraci Kara, B Ozbek Celik, ... Letters in Drug Design & Discovery 14 (6), 647-661, 2017 | 37 | 2017 |
Discovery and structure–activity relationship of plastoquinone analogs as anticancer agents against chronic myelogenous leukemia cells HI Ciftci, N Bayrak, H Yıldırım, M Yıldız, MO Radwan, M Otsuka, M Fujita, ... Archiv der Pharmazie 352 (12), 1900170, 2019 | 30 | 2019 |
Design, synthesis and biological evaluation of pentacyclic triterpene derivatives: Optimization of anti-ABL kinase activity H I. Ciftci, M O. Radwan, S E. Ozturk, NG Ulusoy, E Sozer, D E. Ellakwa, ... Molecules 24 (19), 3535, 2019 | 28 | 2019 |
Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature ME O’Sullivan, F Poitevin, RG Sierra, C Gati, EH Dao, Y Rao, F Aksit, ... Nucleic acids research 46 (18), 9793-9804, 2018 | 27 | 2018 |
Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement MO Radwan, HI Ciftci, TFS Ali, DE Ellakwa, R Koga, H Tateishi, A Nakata, ... Molecules 24 (18), 3295, 2019 | 26 | 2019 |
EGFR-targeted pentacyclic triterpene analogues for glioma therapy HI Ciftci, MO Radwan, B Sever, AK Hamdy, S Emirdağ, NG Ulusoy, ... International Journal of Molecular Sciences 22 (20), 10945, 2021 | 25 | 2021 |
A novel series of chlorinated plastoquinone analogs: Design, synthesis, and evaluation of anticancer activity N Bayrak, H Yıldırım, M Yıldız, MO Radwan, M Otsuka, M Fujita, HI Ciftci, ... Chemical Biology & Drug Design 95 (3), 343-354, 2020 | 25 | 2020 |
A dithiol compound binds to the zinc finger protein TRAF6 and suppresses its ubiquitination R Koga, MO Radwan, T Ejima, Y Kanemaru, H Tateishi, TFS Ali, HI Ciftci, ... ChemMedChem 12 (23), 1935-1941, 2017 | 25 | 2017 |
Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine–pyridine–histidine system TFS Ali, K Iwamaru, HI Ciftci, R Koga, M Matsumoto, Y Oba, H Kurosaki, ... Bioorganic & Medicinal Chemistry 23 (17), 5476-5482, 2015 | 24 | 2015 |
Design, synthesis and investigation of the mechanism of action underlying anti-leukemic effects of the quinolinequinones as LY83583 analogs HI Ciftci, N Bayrak, M Yıldız, H Yıldırım, B Sever, H Tateishi, M Otsuka, ... Bioorganic Chemistry 114, 105160, 2021 | 23 | 2021 |
Anticancer activity of Turkish marine extracts: A purple sponge extract induces apoptosis with multitarget kinase inhibition activity HI Ciftci, M Can, DE Ellakwa, SC Suner, MA Ibrahim, A Oral, N Sekeroglu, ... Investigational New Drugs 38, 1326-1333, 2020 | 22 | 2020 |