| Phase II trial of the histone deacetylase inhibitor pivaloyloxymethyl butyrate (Pivanex, AN-9) in advanced non-small cell lung cancer T Reid, F Valone, W Lipera, D Irwin, W Paroly, R Natale, S Sreedharan, ... Lung cancer 45 (3), 381-386, 2004 | 196 | 2004 |
| Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism MA Cavasin, K Demos-Davies, TR Horn, LA Walker, DD Lemon, ... Circulation research 110 (5), 739-748, 2012 | 181 | 2012 |
| Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension DD Lemon, TR Horn, MA Cavasin, MY Jeong, KW Haubold, CS Long, ... Journal of molecular and cellular cardiology 51 (1), 41-50, 2011 | 135 | 2011 |
| Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress DJ Reuland, S Khademi, CJ Castle, DC Irwin, JM McCord, BF Miller, ... Free Radical Biology and Medicine 56, 102-111, 2013 | 134 | 2013 |
| TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension R Kumar, C Mickael, B Kassa, L Gebreab, JC Robinson, DE Koyanagi, ... Nature communications 8 (1), 15494, 2017 | 113 | 2017 |
| A potential role for reactive oxygen species and the HIF-1α–VEGF pathway in hypoxia-induced pulmonary vascular leak DC Irwin, JM McCord, E Nozik-Grayck, G Beckly, B Foreman, T Sullivan, ... Free Radical Biology and Medicine 47 (1), 55-61, 2009 | 106 | 2009 |
| Neonatal lung side population cells demonstrate endothelial potential and are altered in response to hyperoxia-induced lung simplification D Irwin, K Helm, N Campbell, M Imamura, K Fagan, J Harral, M Carr, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (4 …, 2007 | 104 | 2007 |
| Haptoglobin preserves vascular nitric oxide signaling during hemolysis CA Schaer, JW Deuel, D Schildknecht, L Mahmoudi, I Garcia-Rubio, ... American journal of respiratory and critical care medicine 193 (10), 1111-1122, 2016 | 89 | 2016 |
| Nrf2 activation: a potential strategy for the prevention of acute mountain sickness C Lisk, J McCord, S Bose, T Sullivan, Z Loomis, E Nozik-Grayck, ... Free Radical Biology and Medicine 63, 264-273, 2013 | 85 | 2013 |
| Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension JD West, ED Austin, C Gaskill, S Marriott, R Baskir, G Bilousova, JC Jean, ... American Journal of Physiology-Cell Physiology 307 (5), C415-C430, 2014 | 67 | 2014 |
| Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension B Wojciak-Stothard, VB Abdul-Salam, KH Lao, H Tsang, DC Irwin, C Lisk, ... Circulation 129 (17), 1770-1780, 2014 | 67 | 2014 |
| RhoGTPase in vascular disease D Strassheim, E Gerasimovskaya, D Irwin, EC Dempsey, K Stenmark, ... Cells 8 (6), 551, 2019 | 63 | 2019 |
| Direct ANP inhibition of hypoxia-induced inflammatory pathways in pulmonary microvascular and macrovascular endothelial monolayers DC Irwin, MC Tissot van Patot, A Tucker, R Bowen American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (5 …, 2005 | 61 | 2005 |
| Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated … DC Irwin, JH Baek, K Hassell, R Nuss, P Eigenberger, C Lisk, Z Loomis, ... Free Radical Biology and Medicine 82, 50-62, 2015 | 59 | 2015 |
| Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism PW Buehler, JH Baek, C Lisk, I Connor, T Sullivan, D Kominsky, S Majka, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 303 (4 …, 2012 | 59 | 2012 |
| Sympathetic inhibition attenuates hypoxia induced insulin resistance in healthy adult humans GL Peltonen, RL Scalzo, MM Schweder, DG Larson, GJ Luckasen, D Irwin, ... The Journal of Physiology 590 (11), 2801-2809, 2012 | 56 | 2012 |
| Mice deficient in galectin-1 exhibit attenuated physiological responses to chronic hypoxia-induced pulmonary hypertension D Case, D Irwin, C Ivester, J Harral, K Morris, M Imamura, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (1 …, 2007 | 53 | 2007 |
| Outdoor learning in Aotearoa New Zealand: Voices past, present, and future M Cosgriff, M Legge, M Brown, M Boyes, R Zink, D Irwin Journal of Adventure Education & Outdoor Learning 12 (3), 221-235, 2012 | 52 | 2012 |
| Selective depletion of vascular EC-SOD augments chronic hypoxic pulmonary hypertension E Nozik-Grayck, C Woods, JM Taylor, RKP Benninger, RD Johnson, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 307 …, 2014 | 51 | 2014 |
| Dancing to sustainable tunes: an exploration of music festivals and sustainable practices in Aotearoa S O'Rourke, D Irwin, J Straker Annals of Leisure Research 14 (4), 341-354, 2011 | 46 | 2011 |
