HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen JG Jardine, DW Kulp, C Havenar-Daughton, A Sarkar, B Briney, D Sok, ... Science 351 (6280), 1458-1463, 2016 | 424 | 2016 |
Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies B Briney, D Sok, JG Jardine, DW Kulp, P Skog, S Menis, R Jacak, ... Cell 166 (6), 1459-1470. e11, 2016 | 254 | 2016 |
A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans D Sok, M Pauthner, B Briney, JH Lee, KL Saye-Francisco, J Hsueh, ... Immunity 45 (1), 31-45, 2016 | 142 | 2016 |
Minimally mutated HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design JG Jardine, D Sok, JP Julien, B Briney, A Sarkar, CH Liang, EA Scherer, ... PLoS pathogens 12 (8), e1005815, 2016 | 130 | 2016 |
Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence K Sliepen, BW Han, I Bontjer, P Mooij, F Garces, AJ Behrens, ... Nature communications 10 (1), 2355, 2019 | 127 | 2019 |
The human naive B cell repertoire contains distinct subclasses for a germline-targeting HIV-1 vaccine immunogen C Havenar-Daughton, A Sarkar, DW Kulp, L Toy, X Hu, I Deresa, ... Science translational medicine 10 (448), 2018 | 118 | 2018 |
Glyco3D: A Portal for Structural Glycosciences S Pérez, A Sarkar, A Rivet, C Breton, A Imberty Glycoinformatics, 241-258, 2015 | 105 | 2015 |
Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10 A Irimia, A Sarkar, RL Stanfield, IA Wilson Immunity 44 (1), 21-31, 2016 | 103 | 2016 |
HIV-1 vaccine design through minimizing envelope metastability L He, S Kumar, JD Allen, D Huang, X Lin, CJ Mann, KL Saye-Francisco, ... Science Advances 4 (11), eaau6769, 2018 | 85 | 2018 |
T cells control the generation of nanomolar-affinity anti-glycan antibodies Z Polonskaya, S Deng, A Sarkar, L Kain, M Comellas-Aragones, ... The Journal of clinical investigation 127 (4), 1491-1504, 2017 | 75 | 2017 |
Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design A Irimia, AM Serra, A Sarkar, R Jacak, O Kalyuzhniy, D Sok, ... PLoS pathogens 13 (2), e1006212, 2017 | 73 | 2017 |
Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer A Sarkar, S Bale, AJ Behrens, S Kumar, SK Sharma, N de Val, J Pallesen, ... Nature communications 9 (1), 1956, 2018 | 50 | 2018 |
Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies M Yuan, CA Cottrell, G Ozorowski, MJ van Gils, S Kumar, NC Wu, ... Cell host & microbe 25 (6), 873-883. e5, 2019 | 45 | 2019 |
PolySac3DB: an annotated data base of 3 dimensional structures of polysaccharides A Sarkar, S Pérez BMC bioinformatics 13 (1), 1-12, 2012 | 42 | 2012 |
Deciphering the glycan preference of bacterial lectins by glycan array and molecular docking with validation by microcalorimetry and crystallography J Topin, J Arnaud, A Sarkar, A Audfray, E Gillon, S Perez, H Jamet, ... PloS one 8 (8), 2013 | 36 | 2013 |
Capturing the inherent structural dynamics of the HIV-1 envelope glycoprotein fusion peptide S Kumar, A Sarkar, P Pugach, RW Sanders, JP Moore, AB Ward, ... Nature communications 10 (1), 763, 2019 | 31 | 2019 |
Controlling aggregation propensity in A53T mutant of alpha-synuclein causing Parkinson’s disease S Kumar, A Sarkar, D Sundar Biochemical and biophysical research communications 387 (2), 305-309, 2009 | 25 | 2009 |
ZiF-Predict: a web tool for predicting DNA-binding specificity in C2H2 zinc finger proteins B Molparia, K Goyal, A Sarkar, S Kumar, D Sundar Genomics, Proteomics & Bioinformatics 8 (2), 122-126, 2010 | 20 | 2010 |
Databases of conformations and NMR structures of glycan determinants A Sarkar, S Drouillard, A Rivet, S Perez Glycobiology 25 (12), 1480-1490, 2015 | 18 | 2015 |
A VH1-69 antibody lineage from an infected Chinese donor potently neutralizes HIV-1 by targeting the V3 glycan supersite S Kumar, B Ju, B Shapero, X Lin, L Ren, L Zhang, D Li, Z Zhou, Y Feng, ... Science Advances 6 (38), eabb1328, 2020 | 16 | 2020 |