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Ferhat Alkan
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CRISPR-Cas9 off-targeting assessment with nucleic acid duplex energy parameters
F Alkan, A Wenzel, C Anthon, JH Havgaard, J Gorodkin
Genome biology 19, 1-13, 2018
1272018
BEAMS: backbone extraction and merge strategy for the global many-to-many alignment of multiple PPI networks
F Alkan, C Erten
Bioinformatics 30 (4), 531-539, 2014
932014
RIsearch2: suffix array-based large-scale prediction of RNA–RNA interactions and siRNA off-targets
F Alkan, A Wenzel, O Palasca, P Kerpedjiev, AF Rudebeck, PF Stadler, ...
Nucleic acids research 45 (8), e60-e60, 2017
882017
Good guide, bad guide: spacer sequence-dependent cleavage efficiency of Cas12a
SCA Creutzburg, WY Wu, P Mohanraju, T Swartjes, F Alkan, J Gorodkin, ...
Nucleic acids research 48 (6), 3228-3243, 2020
692020
RAIN: RNA–protein association and interaction networks
A Junge, JC Refsgaard, C Garde, X Pan, A Santos, F Alkan, C Anthon, ...
Database 2017, baw167, 2017
662017
CRISPR/Cas9 gRNA activity depends on free energy changes and on the target PAM context
GI Corsi, K Qu, F Alkan, X Pan, Y Luo, J Gorodkin
Nature Communications 13 (1), 3006, 2022
392022
Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer
S Prekovic, K Schuurman, I Mayayo-Peralta, AG Manjón, M Buijs, S Yavuz, ...
Nature communications 12 (1), 4360, 2021
382021
SiPAN: simultaneous prediction and alignment of protein–protein interaction networks
F Alkan, C Erten
Bioinformatics 31 (14), 2356-2363, 2015
172015
Joint profiling of miRNAs and mRNAs reveals miRNA mediated gene regulation in the Göttingen Minipig obesity model
CMJ Mentzel, F Alkan, H Keinicke, MJ Jacobsen, J Gorodkin, M Fredholm, ...
PLoS One 11 (11), e0167285, 2016
152016
BSGatlas: a unified Bacillus subtilis genome and transcriptome annotation atlas with enhanced information access
AS Geissler, C Anthon, F Alkan, E González-Tortuero, LD Poulsen, ...
Microbial Genomics 7 (2), 000524, 2021
132021
RedNemo: topology-based PPI network reconstruction via repeated diffusion with neighborhood modifications
F Alkan, C Erten
Bioinformatics 33 (4), 537-544, 2017
122017
Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation
J Silva, F Alkan, S Ramalho, G Snieckute, S Prekovic, AK Garcia, ...
Nature Communications 13 (1), 4492, 2022
102022
Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential
Y Malka, F Alkan, S Ju, PR Körner, A Pataskar, E Shulman, ...
Molecular Cell 82 (20), 3840-3855. e8, 2022
92022
Identifying ribosome heterogeneity using ribosome profiling
F Alkan, OG Wilkins, S Hernández-Pérez, S Ramalho, J Silva, J Ule, ...
Nucleic Acids Research 50 (16), e95-e95, 2022
82022
Ribo-ODDR: Oligo design pipeline for experiment-specific rRNA depletion in ribo-seq
F Alkan, J Silva, EP Barberŕ, WJ Faller
Bioinformatics, 2021
62021
CRISPRi screen for enhancing heterologous α-amylase yield in Bacillus subtilis
AS Geissler, AO Fehler, LD Poulsen, E González-Tortuero, ...
Journal of Industrial Microbiology and Biotechnology 50 (1), kuac028, 2023
42023
Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
CP Lin, PL Levy, A Alflen, G Apriamashvili, MA Ligtenberg, ...
Cancer Cell 42 (4), 623-645. e10, 2024
12024
Structure of conflict graphs in constraint alignment problems and algorithms
F Alkan, T Býyýkođlu, M Demange, C Erten
Discrete Mathematics & Theoretical Computer Science 21 (4), 2019
12019
RNA dicing regulates the expression of an oncogenic JAK1 isoform
Y Malka, R van der Kammen, S Ju, F Alkan, C Lee, WJ Faller
bioRxiv, 2024.02. 20.581186, 2024
2024
An" alert state" ribosome population acts as a master regulator of cytokine mediated processes
A Dopler, F Alkan, Y Malka, K Hoefakker, OI Isaeva, M Kerkhoff, ...
bioRxiv, 2023.10. 17.562425, 2023
2023
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Articles 1–20