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Yıl
Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity
K Valko, S Nunhuck, C Bevan, MH Abraham, DP Reynolds
Journal of pharmaceutical sciences 92 (11), 2236-2248, 2003
3942003
Estimation of volume of distribution in humans from high throughput HPLC-based measurements of human serum albumin binding and immobilized artificial membrane partitioning
F Hollósy, K Valkó, A Hersey, S Nunhuck, G Kéri, C Bevan
Journal of medicinal chemistry 49 (24), 6958-6971, 2006
1102006
Estimating unbound volume of distribution and tissue binding by in vitro HPLC-based human serum albumin and immobilised artificial membrane-binding measurements
KL Valkó, SB Nunhuck, AP Hill
Journal of pharmaceutical sciences 100 (3), 849-862, 2011
512011
Physicochemical profile of macrolides and their comparison with small molecules
V Stepanić, D Žiher, V Gabelica-Marković, D Jelić, S Nunhuck, K Valko, ...
European journal of medicinal chemistry 47, 462-472, 2012
492012
In vitro measurement of drug efficiency index to aid early lead optimization
K Valko, E Chiarparin, S Nunhuck, D Montanari
Journal of pharmaceutical sciences 101 (11), 4155-4169, 2012
442012
Using physicochemical measurements to influence better compound design
SB Bunally, CN Luscombe, RJ Young
SLAS DISCOVERY: Advancing Life Sciences R&D 24 (8), 791-801, 2019
322019
The role and impact of high throughput biomimetic measurements in drug discovery
S Bunally, RJ Young
ADMET and DMPK 6 (2), 74-84, 2018
282018
Revisiting the application of Immobilized Artificial Membrane (IAM) chromatography to estimate in vivo distribution properties of drug discovery compounds based on the model of …
K Valko, S Rava, S Bunally, S Anderson
Admet and Dmpk 8 (1), 78-97, 2020
102020
In Vivo Half-Life Extension of BMP1/TLL Metalloproteinase Inhibitors Using Small-Molecule Human Serum Albumin Binders
JC Vantourout, AM Mason, J Yuen, GL Simpson, G Evindar, L Kuai, ...
Bioconjugate Chemistry 32 (2), 279-289, 2021
42021
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