Tuomo Kalliokoski
Tuomo Kalliokoski
Senior Scientist at Orion Pharma
Verified email at orionpharma.com
Title
Cited by
Cited by
Year
Comparability of mixed IC 50 data–a statistical analysis
T Kalliokoski, C Kramer, A Vulpetti, P Gedeck
PloS one 8 (4), e61007, 2013
1862013
The Experimental Uncertainty of Heterogeneous Public Ki Data
C Kramer, T Kalliokoski, P Gedeck, A Vulpetti
Journal of medicinal chemistry 55 (11), 5165-5173, 2012
1652012
Expansion of chemical space for collaborative lead generation and drug discovery: the European Lead Factory Perspective
A Karawajczyk, F Giordanetto, J Benningshof, D Hamza, T Kalliokoski, ...
Drug Discovery Today 20 (11), 1310-1316, 2015
722015
The effect of ligand-based tautomer and protomer prediction on structure-based virtual screening
T Kalliokoski, HS Salo, M Lahtela-Kakkonen, A Poso
Journal of chemical information and modeling 49 (12), 2742-2748, 2009
602009
Price-focused analysis of commercially available building blocks for combinatorial library synthesis
T Kalliokoski
ACS combinatorial science 17 (10), 600-607, 2015
312015
Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs
SA Khan, A Faisal, JP Mpindi, JA Parkkinen, T Kalliokoski, A Poso, ...
BMC bioinformatics 13 (1), 1-15, 2012
282012
Chemogenomics in drug discovery: computational methods based on the comparison of binding sites
A Vulpetti, T Kalliokoski, F Milletti
Future medicinal chemistry 4 (15), 1971-1979, 2012
282012
Design and synthesis of DNA-encoded libraries based on a benzodiazepine and a pyrazolopyrimidine scaffold
MK Škopić, O Bugain, K Jung, S Onstein, S Brandherm, T Kalliokoski, ...
MedChemComm 7 (10), 1957-1965, 2016
242016
Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries
P Craven, A Aimon, M Dow, N Fleury-Bregeot, R Guilleux, R Morgentin, ...
Bioorganic & medicinal chemistry 23 (11), 2629-2635, 2015
222015
Quality issues with public domain chemogenomics data
T Kalliokoski, C Kramer, A Vulpetti
Molecular informatics 32 (11‐12), 898-905, 2013
222013
Subpocket analysis method for fragment-based drug discovery
T Kalliokoski, TSG Olsson, A Vulpetti
Journal of chemical information and modeling 53 (1), 131-141, 2013
192013
Discovery of novel cannabinoid receptor ligands by a virtual screening approach: further development of 2, 4, 6-trisubstituted 1, 3, 5-triazines as CB2 agonists
S Yrjölä, T Kalliokoski, T Laitinen, A Poso, T Parkkari, T Nevalainen
European Journal of Pharmaceutical Sciences 48 (1-2), 9-20, 2013
192013
Exploitation of the Ugi-Joullie reaction in the synthesis of libraries of drug-like bicyclic hydantoins
JD Firth, R Zhang, R Morgentin, R Guilleux, T Kalliokoski, S Warriner, ...
Synthesis 47 (16), 2391-2406, 2015
162015
Aminomethylhydroxylation of alkenes: Exploitation in the synthesis of scaffolds for small molecule libraries
I Colomer, O Adeniji, GM Burslem, P Craven, MO Rasmussen, A Willaume, ...
Bioorganic & medicinal chemistry 23 (11), 2736-2740, 2015
142015
Translation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory
R Morgentin, M Dow, A Aimon, G Karageorgis, T Kalliokoski, D Roche, ...
Drug discovery today 23 (9), 1578-1583, 2018
112018
Realisation of small molecule libraries based on frameworks distantly related to natural products
A Aimon, G Karageorgis, J Masters, M Dow, PGE Craven, M Ohsten, ...
Organic & biomolecular chemistry 16 (17), 3160-3167, 2018
112018
Large-scale evaluation of CavBase for analyzing the polypharmacology of Kinase inhibitors
T Kalliokoski, A Vulpetti
Molecular informatics 30 (11/12), 923-925, 2011
82011
FieldChopper, a new tool for automatic model generation and virtual screening based on molecular fields
T Kalliokoski, T Ronkko, A Poso
Journal of chemical information and modeling 48 (6), 1131-1137, 2008
52008
Increasing the Throughput of Shape‐Based Virtual Screening with GPU Processing and Single Conformation Databases
T Kalliokoski, TP Ronkko, A Poso
Molecular informatics 29 (4), 293-296, 2010
32010
Predicting pKa for Small Molecules on Public and In‐house Datasets Using Fast Prediction Methods Combined with Data Fusion
T Kalliokoski, K Sinervo
Molecular informatics 38 (7), 1800163, 2019
22019
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Articles 1–20