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Jens Brodbeck
Jens Brodbeck
Revolution Medicines
Verified email at revmed.com
Title
Cited by
Cited by
Year
Tau reduction prevents Aβ-induced defects in axonal transport
KA Vossel, K Zhang, J Brodbeck, AC Daub, P Sharma, S Finkbeiner, ...
Science 330 (6001), 198-198, 2010
5862010
Ducky mouse phenotype of epilepsy and ataxia is associated with mutations in the Cacna2d2 gene and decreased calcium channel current in cerebellar Purkinje cells
J Barclay, N Balaguero, M Mione, SL Ackerman, VA Letts, J Brodbeck, ...
Journal of Neuroscience 21 (16), 6095-6104, 2001
3912001
Effect of selective LRRK2 kinase inhibition on nonhuman primate lung
RN Fuji, M Flagella, M Baca, MA S. Baptista, J Brodbeck, BK Chan, ...
Science translational medicine 7 (273), 273ra15-273ra15, 2015
2902015
The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated α2δ-2 protein with abnormal function
J Brodbeck, A Davies, JM Courtney, A Meir, N Balaguero, C Canti, ...
Journal of Biological Chemistry 277 (10), 7684-7693, 2002
2002002
Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons
HK Chen, Z Liu, A Meyer-Franke, J Brodbeck, RD Miranda, JG McGuire, ...
Journal of Biological Chemistry 287 (8), 5253-5266, 2012
1532012
Intron-3 retention/splicing controls neuronal expression of apolipoprotein E in the CNS
Q Xu, D Walker, A Bernardo, J Brodbeck, ME Balestra, Y Huang
Journal of Neuroscience 28 (6), 1452-1459, 2008
1192008
Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons
J Brodbeck, ME Balestra, AM Saunders, AD Roses, RW Mahley, Y Huang
Proceedings of the National Academy of Sciences 105 (4), 1343-1346, 2008
1192008
Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors
J Brodbeck, J McGuire, Z Liu, A Meyer-Franke, ME Balestra, D Jeong, ...
Journal of biological chemistry 286 (19), 17217-17226, 2011
1102011
Voltage‐dependent binding and calcium channel current inhibition by an anti‐α1D subunit antibody in rat dorsal root ganglion neurones and guinea‐pig myocytes
CN Wyatt, V Campbell, J Brodbeck, NL Brice, KM Page, NS Berrow, ...
The Journal of Physiology 502 (2), 307-319, 1997
501997
Arf4 determines dentate gyrus-mediated pattern separation by regulating dendritic spine development
S Jain, SY Yoon, L Zhu, J Brodbeck, J Dai, D Walker, Y Huang
Public Library of Science 7 (9), e46340, 2012
472012
The role of glomerular epithelial injury in kidney function decline in patients with diabetic kidney disease in the TRIDENT cohort
MB Palmer, A Abedini, C Jackson, S Blady, S Chatterjee, KM Sullivan, ...
Kidney international reports 6 (4), 1066-1080, 2021
232021
Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer
MA Jarzabek, WR Proctor, J Vogt, R Desai, P Dicker, G Cain, R Raja, ...
PLoS One 13 (6), e0198099, 2018
122018
P2‐157: Apolipoprotein E4 impairs mitochondrial function and increases reactive oxygen species in neuronal cells
J Brodbeck, RD Miranda, SB Freedman, KH Weisgraber, RW Mahley, ...
Alzheimer's & Dementia 5 (4S_Part_10), P307-P307, 2009
82009
O3‐03–03: Apolipoprotein E4 and its fragment impair mitochondrial dynamics in neuronal cultures
J Brodbeck, M Balestra, S Freedman, KH Weisgraber, RW Mahley, ...
Alzheimer's & Dementia 4, T163-T163, 2008
52008
Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells
A Aggarwal, PM Odorizzi, J Brodbeck, N van Buuren, C Moon, S Chang, ...
JHEP Reports 5 (4), 100664, 2023
32023
Automated breast cancer image classification based on integration of noisy-and model and fully connected network
CH Huang, J Brodbeck, NM Dimaano, J Kang, B Dogdas, D Rollins, ...
Image Analysis and Recognition: 15th International Conference, ICIAR 2018 …, 2018
22018
Methods of identifying agents that modulate mitochondrial function
Y Huang, J Brodbeck
US Patent 8,512,958, 2013
22013
Reduction in voltage-dependent calcium channel function in cerebellar Purkinje cells of the mouse mutant ducky, which has a null mutation for the calcium channel accessory …
N Balaguero, J Barclay, M Mione, C Canti, J Brodbeck, RM Gardiner, ...
J PHYSIOL-LONDON 527, 112P-112P, 2000
22000
Mucosal p-STAT1/3 correlates with histologic disease activity in Crohn’s disease and is responsive to filgotinib
W Reinisch, A Serone, X Hébuterne, T Kühbacher, M Kłopocka, X Roblin, ...
Tissue Barriers 11 (2), 2088961, 2023
12023
Quantification of HBV hepatocyte burden using novel multiplex immunofluorescence staining and image analysis reveals substantial reduction in HBV liver burden with anti-viral …
A Aggarwal, P Odorizzi, J Brodbeck, N Van Buuren, C Moon, S Chang, ...
Journal of Hepatology 77, S832, 2022
12022
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