Takip et
Mark Woodford
Mark Woodford
upstate.edu üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Post-translational modifications of Hsp90 and translating the chaperone code
SJ Backe, RA Sager, MR Woodford, AM Makedon, M Mollapour
Journal of Biological Chemistry 295 (32), 11099-11117, 2020
1322020
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors
M Mollapour, D Bourboulia, K Beebe, MR Woodford, S Polier, A Hoang, ...
Molecular cell 53 (2), 317-329, 2014
1302014
Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients
MR Woodford, RA Sager, E Marris, DM Dunn, AR Blanden, RL Murphy, ...
The EMBO journal 36 (24), 3650-3665, 2017
792017
Structural and functional basis of protein phosphatase 5 substrate specificity
J Oberoi, DM Dunn, MR Woodford, L Mariotti, J Schulman, D Bourboulia, ...
Proceedings of the National Academy of Sciences 113 (32), 9009-9014, 2016
742016
Mps1 mediated phosphorylation of Hsp90 confers renal cell carcinoma sensitivity and selectivity to Hsp90 inhibitors
MR Woodford, AW Truman, DM Dunn, SM Jensen, R Cotran, R Bullard, ...
Cell reports 14 (4), 872-884, 2016
662016
c-Abl mediated tyrosine phosphorylation of Aha1 activates its co-chaperone function in cancer cells
DM Dunn, MR Woodford, AW Truman, SM Jensen, J Schulman, T Caza, ...
Cell reports 12 (6), 1006-1018, 2015
632015
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding
MR Woodford, DM Dunn, AR Blanden, D Capriotti, D Loiselle, ...
Nature communications 7 (1), 12037, 2016
622016
Co-chaperones TIMP2 and AHA1 competitively regulate extracellular HSP90: client MMP2 activity and matrix proteolysis
AJ Baker-Williams, F Hashmi, MA Budzyński, MR Woodford, S Gleicher, ...
Cell reports 28 (7), 1894-1906. e6, 2019
562019
Chemical perturbation of oncogenic protein folding: from the prediction of locally unstable structures to the design of disruptors of Hsp90–client interactions
A Paladino, MR Woodford, SJ Backe, RA Sager, P Kancherla, ...
Chemistry–A European Journal 26 (43), 9459-9465, 2020
492020
Impact of posttranslational modifications on the anticancer activity of Hsp90 inhibitors
MR Woodford, D Dunn, JB Miller, S Jamal, L Neckers, M Mollapour
Advances in cancer research 129, 31-50, 2016
442016
Phosphorylation and ubiquitination regulate protein phosphatase 5 activity and its prosurvival role in kidney cancer
N Dushukyan, DM Dunn, RA Sager, MR Woodford, DR Loiselle, ...
Cell reports 21 (7), 1883-1895, 2017
422017
Post-translational regulation of FNIP1 creates a rheostat for the molecular chaperone Hsp90
RA Sager, MR Woodford, SJ Backe, AM Makedon, AJ Baker-Williams, ...
Cell reports 26 (5), 1344-1356. e5, 2019
382019
Structural and functional regulation of lactate dehydrogenase-A in cancer
MR Woodford, VZ Chen, SJ Backe, G Bratslavsky, M Mollapour
Future Medicinal Chemistry 12 (5), 439-455, 2019
362019
Extracellular phosphorylation of TIMP-2 by secreted c-Src tyrosine kinase controls MMP-2 activity
J Sánchez-Pozo, AJ Baker-Williams, MR Woodford, R Bullard, B Wei, ...
Iscience 1, 87-96, 2018
282018
Structure and function of the co-chaperone protein phosphatase 5 in cancer
RA Sager, N Dushukyan, M Woodford, M Mollapour
Cell Stress and Chaperones 25 (3), 383-394, 2020
252020
The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect
MR Woodford, AJ Baker-Williams, RA Sager, SJ Backe, AR Blanden, ...
Nature structural & molecular biology 28 (8), 662-670, 2021
242021
TRAP1 chaperones the metabolic switch in cancer
LA Wengert, SJ Backe, D Bourboulia, M Mollapour, MR Woodford
Biomolecules 12 (6), 786, 2022
182022
Design of disruptors of the Hsp90–Cdc37 Interface
I D’Annessa, N Hurwitz, V Pirota, GL Beretta, S Tinelli, M Woodford, ...
Molecules 25 (2), 360, 2020
182020
Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity
MR Woodford, M Hughes, RA Sager, SJ Backe, AJ Baker-Williams, ...
Oncotarget 10 (56), 5824, 2019
182019
Detecting posttranslational modifications of Hsp90
RA Sager, MR Woodford, L Neckers, M Mollapour
Chaperones: Methods and Protocols, 209-219, 2018
182018
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Makaleler 1–20