Marketa Zvelebil
Marketa Zvelebil
Assistant Professor in Cancer Informatics, ICR
Verified email at icr.ac.uk
Title
Cited by
Cited by
Year
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction.
MP Wymann, G Bulgarelli-Leva, MJ Zvelebil, L Pirola, B Vanhaesebroeck, ...
Molecular and cellular biology 16 (4), 1722-1733, 1996
8231996
The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective …
AJ Folkes, K Ahmadi, WK Alderton, S Alix, SJ Baker, G Box, ...
Journal of medicinal chemistry 51 (18), 5522-5532, 2008
7402008
Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase.
K Salim, MJ Bottomley, E Querfurth, MJ Zvelebil, I Gout, R Scaife, ...
The EMBO journal 15 (22), 6241-6250, 1996
6691996
Prediction of protein secondary structure and active sites using the alignment of homologous sequences
MJ Zvelebil, GJ Barton, WR Taylor, MJE Sternberg
Journal of molecular biology 195 (4), 957-961, 1987
5481987
Phosphoinositide 3-kinase signalling–which way to target?
MP Wymann, M Zvelebil, M Laffargue
Trends in pharmacological sciences 24 (7), 366-376, 2003
5472003
P110δ, a novel phosphoinositide 3-kinase in leukocytes
B Vanhaesebroeck, MJ Welham, K Kotani, R Stein, PH Warne, ...
Proceedings of the National Academy of Sciences 94 (9), 4330-4335, 1997
5371997
Exploring the specificity of the PI3K family inhibitor LY294002
SI Gharbi, MJ Zvelebil, SJ Shuttleworth, T Hancox, N Saghir, JF Timms, ...
Biochemical Journal 404 (1), 15-21, 2007
4232007
A human phosphatidylinositol 3‐kinase complex related to the yeast Vps34p‐Vps15p protein sorting system.
S Volinia, R Dhand, B Vanhaesebroeck, LK MacDougall, R Stein, ...
The EMBO journal 14 (14), 3339-3348, 1995
4231995
Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit
N Miled, Y Yan, WC Hon, O Perisic, M Zvelebil, Y Inbar, ...
science 317 (5835), 239-242, 2007
3862007
Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system
S Gharbi, P Gaffney, A Yang, MJ Zvelebil, R Cramer, MD Waterfield, ...
Molecular & Cellular Proteomics 1 (2), 91-98, 2002
3682002
Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin
J DOMIN, S Volinia, SE RITTENHOUSE, MJ ZVELEBIL, RC STEIN, ...
Biochemical Journal 326 (1), 139-147, 1997
3121997
A novel point mutation in the tyrosine kinase domain of the RET proto-oncogene in sporadic medullary thyroid carcinoma and in a family with FMTC.
C Eng, DP Smith, LM Mulligan, CS Healey, MJ Zvelebil, TJ Stonehouse, ...
Oncogene 10 (3), 509-513, 1995
3011995
iASPP preferentially binds p53 proline-rich region and modulates apoptotic function of codon 72–polymorphic p53
D Bergamaschi, Y Samuels, A Sullivan, M Zvelebil, H Breyssens, A Bisso, ...
Nature genetics 38 (10), 1133-1141, 2006
2952006
Phosphatidylinositol 3-kinase is required for the expression but not for the induction or the maintenance of long-term potentiation in the hippocampal CA1 region
PP Sanna, M Cammalleri, F Berton, C Simpson, R Lutjens, FE Bloom, ...
Journal of Neuroscience 22 (9), 3359-3365, 2002
2862002
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis
M Gyrd-Hansen, M Darding, M Miasari, MM Santoro, L Zender, W Xue, ...
Nature cell biology 10 (11), 1309-1317, 2008
2692008
Proteomic definition of normal human luminal and myoepithelial breast cells purified from reduction mammoplasties
MJ Page, B Amess, RR Townsend, R Parekh, A Herath, L Brusten, ...
Proceedings of the National Academy of Sciences 96 (22), 12589-12594, 1999
2561999
Identification of a disease-defining gene fusion in epithelioid hemangioendothelioma
MR Tanas, A Sboner, AM Oliveira, MR Erickson-Johnson, J Hespelt, ...
Science translational medicine 3 (98), 98ra82-98ra82, 2011
2492011
Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cγ1, Grb2, and Src family kinases
CH Reynolds, CJ Garwood, S Wray, C Price, S Kellie, T Perera, ...
Journal of Biological Chemistry 283 (26), 18177-18186, 2008
2332008
Understanding bioinformatics
MJ Zvelebil, JO Baum
Garland Science, 2007
2232007
Perforin is activated by a proteolytic cleavage during biosynthesis which reveals a phospholipid‐binding C2 domain
R Uellner, MJ Zvelebil, J Hopkins, J Jones, LK MacDougall, BP Morgan, ...
The EMBO journal 16 (24), 7287-7296, 1997
2151997
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