Mutations in PTEN Are Frequent in Endometrial Carcinoma But Rare in Other Common Gynecological Malignancies H Tashiro, MS Blazes, R Wu, KR Cho, S Bose, SI Wang, J Li, R Parsons, ... Cancer research 57 (18), 3935-3940, 1997 | 986 | 1997 |
Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas DR Schwartz, SLR Kardia, KA Shedden, R Kuick, G Michailidis, ... Cancer research 62 (16), 4722-4729, 2002 | 487 | 2002 |
Activation of AXIN2 expression by β-catenin-T cell factor: a feedback repressor pathway regulating Wnt signaling JY Leung, FT Kolligs, R Wu, Y Zhai, R Kuick, S Hanash, KR Cho, ... Journal of Biological Chemistry 277 (24), 21657-21665, 2002 | 451 | 2002 |
Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/β-catenin and PI3K/Pten signaling pathways R Wu, N Hendrix-Lucas, R Kuick, Y Zhai, DR Schwartz, A Akyol, ... Cancer cell 11 (4), 321-333, 2007 | 370 | 2007 |
Diverse mechanisms of β-catenin deregulation in ovarian endometrioid adenocarcinomas R Wu, Y Zhai, ER Fearon, KR Cho Cancer research 61 (22), 8247-8255, 2001 | 350 | 2001 |
Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas ND Hendrix, R Wu, R Kuick, DR Schwartz, ER Fearon, KR Cho Cancer research 66 (3), 1354-1362, 2006 | 336 | 2006 |
Molecular genetic evidence supporting the clonality and appendiceal origin of pseudomyxoma peritonei in women C Szych, A Staebler, DC Connolly, R Wu, KR Cho, BM Ronnett The American journal of pathology 154 (6), 1849-1855, 1999 | 291 | 1999 |
Loss of FHIT Expression in Cervical Carcinoma Cell Lines and Primary Tumors DL Greenspan, DC Connolly, R Wu, RY Lei, JTC Vogelstein, YT Kim, ... Cancer research 57 (21), 4692-4698, 1997 | 222 | 1997 |
ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with β-catenin defects and promotes neoplastic transformation FT Kolligs, MT Nieman, I Winer, G Hu, D Van Mater, Y Feng, IM Smith, ... Cancer cell 1 (2), 145-155, 2002 | 215 | 2002 |
Novel candidate targets of β-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas DR Schwartz, R Wu, SLR Kardia, AM Levin, CC Huang, KA Shedden, ... Cancer research 63 (11), 2913-2922, 2003 | 195 | 2003 |
The hepatocyte nuclear factor 3 α gene, HNF3α (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas L Lin, CT Miller, JI Contreras, MS Prescott, SL Dagenais, R Wu, J Yee, ... Cancer research 62 (18), 5273-5279, 2002 | 175 | 2002 |
Role of β-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas Y Zhai, R Wu, DR Schwartz, D Darrah, H Reed, FT Kolligs, MT Nieman, ... The American journal of pathology 160 (4), 1229-1238, 2002 | 132 | 2002 |
Loss of fhit expression in invasive cervical carcinomas and intraepithelial lesions associated with invasive disease DC Connolly, DL Greenspan, R Wu, X Ren, RL Dunn, KV Shah, ... Clinical cancer research 6 (9), 3505-3510, 2000 | 114 | 2000 |
Neurofibromin 1 (NF1) defects are common in human ovarian serous carcinomas and co-occur with TP53 mutations N Sangha, R Wu, R Kuick, S Powers, D Mu, D Fiander, K Yuen, ... Neoplasia 10 (12), 1362-IN9, 2008 | 93 | 2008 |
CD24+ Ovarian Cancer Cells Are Enriched for Cancer-Initiating Cells and Dependent on JAK2 Signaling for Growth and Metastasis D Burgos-Ojeda, R Wu, K McLean, YC Chen, M Talpaz, E Yoon, KR Cho, ... Molecular cancer therapeutics 14 (7), 1717-1727, 2015 | 92 | 2015 |
High‐grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease Y Zhai, R Wu, R Kuick, MS Sessine, S Schulman, M Green, ER Fearon, ... The Journal of pathology 243 (1), 16-25, 2017 | 91 | 2017 |
New models of hematogenous ovarian cancer metastasis demonstrate preferential spread to the ovary and a requirement for the ovary for abdominal dissemination LG Coffman, D Burgos-Ojeda, R Wu, K Cho, S Bai, RJ Buckanovich Translational Research 175, 92-102. e2, 2016 | 89 | 2016 |
Amplification and overexpression of the L-MYC proto-oncogene in ovarian carcinomas R Wu, L Lin, DG Beer, LH Ellenson, BJ Lamb, JM Rouillard, R Kuick, ... The American journal of pathology 162 (5), 1603-1610, 2003 | 89 | 2003 |
Lymph node metastases in colon cancer are polyclonal PJ Ulintz, JK Greenson, R Wu, ER Fearon, KM Hardiman Clinical Cancer Research 24 (9), 2214-2224, 2018 | 83 | 2018 |
Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma R Wu, TC Hu, A Rehemtulla, ER Fearon, KR Cho Clinical Cancer Research 17 (23), 7359-7372, 2011 | 76 | 2011 |