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| Integrated genomics and proteomics define huntingtin CAG length–dependent networks in mice P Langfelder, JP Cantle, D Chatzopoulou, N Wang, F Gao, I Al-Ramahi, ... Nature neuroscience 19 (4), 623-633, 2016 | 363 | 2016 |
| Corticosteroids regulate brain hippocampal 5-HT1A receptor mRNA expression DT Chalmers, SP Kwak, A Mansour, H Akil, SJ Watson Journal of Neuroscience 13 (3), 914-923, 1993 | 318 | 1993 |
| CAG repeat not polyglutamine length determines timing of Huntington’s disease onset JM Lee, K Correia, J Loupe, KH Kim, D Barker, EP Hong, MJ Chao, ... Cell 178 (4), 887-900. e14, 2019 | 268 | 2019 |
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| Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease JP Miller, J Holcomb, I Al-Ramahi, M De Haro, J Gafni, N Zhang, E Kim, ... Neuron 67 (2), 199-212, 2010 | 208 | 2010 |
| Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene. SP Kwak, DJ Hakes, KJ Martell, JE Dixon Journal of Biological Chemistry 269 (5), 3596-3604, 1994 | 197 | 1994 |
| Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease B Zeitler, S Froelich, K Marlen, DA Shivak, Q Yu, D Li, JR Pearl, JC Miller, ... Nature medicine 25 (7), 1131-1142, 2019 | 163 | 2019 |
| Multiple Dual Specificity Protein Tyrosine Phosphatases Are Expressed and Regulated Differentially in Liver Cell Lines (∗) SP Kwak, JE Dixon Journal of Biological Chemistry 270 (3), 1156-1160, 1995 | 152 | 1995 |
| The HTT CAG-expansion mutation determines age at death but not disease duration in Huntington disease JW Keum, A Shin, T Gillis, JS Mysore, KA Elneel, D Lucente, T Hadzi, ... The American Journal of Human Genetics 98 (2), 287-298, 2016 | 146 | 2016 |
| hVH‐5: A protein tyrosine phosphatase abundant in brain that inactivates mitogen‐activated protein kinase KJ Martell, AF Seasholtz, SP Kwak, KK Clemens, JE Dixon Journal of neurochemistry 65 (4), 1823-1833, 1995 | 137 | 1995 |
| A genetic association study of glutamine-encoding DNA sequence structures, somatic CAG expansion, and DNA repair gene variants, with Huntington disease clinical outcomes M Ciosi, A Maxwell, SA Cumming, DJH Moss, AM Alshammari, MD Flower, ... EBioMedicine 48, 568-580, 2019 | 133 | 2019 |
| Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington’s disease XH Lu, VB Mattis, N Wang, I Al-Ramahi, N van den Berg, SA Fratantoni, ... Science translational medicine 6 (268), 268ra178-268ra178, 2014 | 128 | 2014 |
| Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis ELF Holzbaur, DS Howland, N Weber, K Wallace, Y She, S Kwak, ... Neurobiology of disease 23 (3), 697-707, 2006 | 128 | 2006 |
| Characterization of the WAVE1 knock-out mouse: implications for CNS development JP Dahl, J Wang-Dunlop, C Gonzales, MEP Goad, RJ Mark, SP Kwak Journal of Neuroscience 23 (8), 3343-3352, 2003 | 128 | 2003 |
| 5'-Heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splice variants within the rat hippocampus SP Kwak, PD Patel, RC Thompson, H Akil, SJ Watson Endocrinology 133 (5), 2344-2350, 1993 | 124 | 1993 |
| WAVE1 is required for oligodendrocyte morphogenesis and normal CNS myelination HJ Kim, AB DiBernardo, JA Sloane, MN Rasband, D Solomon, B Kosaras, ... Journal of Neuroscience 26 (21), 5849-5859, 2006 | 115 | 2006 |
| A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium KM Walton, KJ Martell, SP Kwak, JE Dixon, BL Largent Neuron 11 (2), 387-400, 1993 | 98 | 1993 |
| A modifier of Huntington's disease onset at the MLH1 locus JM Lee, MJ Chao, D Harold, K Abu Elneel, T Gillis, P Holmans, L Jones, ... Human molecular genetics 26 (19), 3859-3867, 2017 | 97 | 2017 |
