| RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia J Zuber, J Shi, E Wang, AR Rappaport, H Herrmann, EA Sison, D Magoon, ... Nature 478 (7370), 524-528, 2011 | 2093 | 2011 |
| Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains J Shi, E Wang, JP Milazzo, Z Wang, JB Kinney, CR Vakoc Nature biotechnology 33 (6), 661-667, 2015 | 757 | 2015 |
| Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation J Shi, WA Whyte, CJ Zepeda-Mendoza, JP Milazzo, C Shen, JS Roe, ... Genes & development 27 (24), 2648-2662, 2013 | 472 | 2013 |
| An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance J Zuber, AR Rappaport, W Luo, E Wang, C Chen, AV Vaseva, J Shi, ... Genes & development 25 (15), 1628-1640, 2011 | 297 | 2011 |
| Targeting an RNA-binding protein network in acute myeloid leukemia E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ... Cancer cell 35 (3), 369-384. e7, 2019 | 247 | 2019 |
| A reconfigured pattern of MLL occupancy within mitotic chromatin promotes rapid transcriptional reactivation following mitotic exit GA Blobel, S Kadauke, E Wang, AW Lau, J Zuber, MM Chou, CR Vakoc Molecular cell 36 (6), 970-983, 2009 | 214 | 2009 |
| Targeting mitochondrial structure sensitizes acute myeloid leukemia to venetoclax treatment X Chen, C Glytsou, H Zhou, S Narang, DE Reyna, A Lopez, ... Cancer discovery 9 (7), 890-909, 2019 | 203 | 2019 |
| RNA splicing and cancer E Wang, I Aifantis Trends in cancer 6 (8), 631-644, 2020 | 166 | 2020 |
| NSD3-short is an adaptor protein that couples BRD4 to the CHD8 chromatin remodeler C Shen, JJ Ipsaro, J Shi, JP Milazzo, E Wang, JS Roe, Y Suzuki, ... Molecular cell 60 (6), 847-859, 2015 | 155 | 2015 |
| Pharmacologic modulation of RNA splicing enhances anti-tumor immunity SX Lu, E De Neef, JD Thomas, E Sabio, B Rousseau, M Gigoux, DA Knorr, ... Cell 184 (15), 4032-4047. e31, 2021 | 152 | 2021 |
| Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia E Wang, S Kawaoka, M Yu, J Shi, T Ni, W Yang, J Zhu, RG Roeder, ... Proceedings of the National Academy of Sciences 110 (10), 3901-3906, 2013 | 151 | 2013 |
| The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9; NrasG12D acute myeloid leukemia J Shi, E Wang, J Zuber, A Rappaport, M Taylor, C Johns, SW Lowe, ... Oncogene 32 (7), 930-938, 2013 | 132 | 2013 |
| Mechanisms of resistance to noncovalent Bruton’s tyrosine kinase inhibitors E Wang, X Mi, MC Thompson, S Montoya, RQ Notti, J Afaghani, ... New England Journal of Medicine 386 (8), 735-743, 2022 | 116 | 2022 |
| MED12 regulates HSC-specific enhancers independently of mediator kinase activity to control hematopoiesis B Aranda-Orgilles, R Saldaņa-Meyer, E Wang, E Trompouki, A Fassl, ... Cell stem cell 19 (6), 784-799, 2016 | 113 | 2016 |
| The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia D Papaioannou, A Petri, OM Dovey, S Terreri, E Wang, FA Collins, ... Nature communications 10 (1), 5351, 2019 | 83 | 2019 |
| Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition D Inoue, JT Polaski, J Taylor, P Castel, S Chen, S Kobayashi, SJ Hogg, ... Nature genetics 53 (5), 707-718, 2021 | 75 | 2021 |
| Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies GM Matthews, P Mehdipour, LA Cluse, KJ Falkenberg, E Wang, M Roth, ... Blood, The Journal of the American Society of Hematology 126 (21), 2392-2403, 2015 | 57 | 2015 |
| The HDAC3–SMARCA4–miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma N Bharathy, NE Berlow, E Wang, J Abraham, TP Settelmeyer, JE Hooper, ... Science signaling 11 (557), eaau7632, 2018 | 56 | 2018 |
| Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation E Wang, H Zhou, B Nadorp, G Cayanan, X Chen, AH Yeaton, S Nomikou, ... Cell Stem Cell 28 (4), 718-731. e6, 2021 | 45 | 2021 |
| Valine tRNA levels and availability regulate complex I assembly in leukaemia P Thandapani, A Kloetgen, MT Witkowski, C Glytsou, AK Lee, E Wang, ... Nature 601 (7893), 428-433, 2022 | 44 | 2022 |
