| A single autoimmune T cell receptor recognizes more than a million different peptides L Wooldridge, J Ekeruche-Makinde, H Van Den Berg, A Skowera, ... Journal of Biological Chemistry 287 (2), 1168-1177, 2012 | 497 | 2012 |
| Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses DA Price, JM Brenchley, LE Ruff, MR Betts, BJ Hill, M Roederer, RA Koup, ... The Journal of experimental medicine 202 (10), 1349-1361, 2005 | 462 | 2005 |
| Structural and kinetic basis for heightened immunogenicity of T cell vaccines JL Chen, G Stewart-Jones, G Bossi, NM Lissin, L Wooldridge, EML Choi, ... The Journal of experimental medicine 201 (8), 1243-1255, 2005 | 308 | 2005 |
| Different T cell receptor affinity thresholds and CD8 coreceptor dependence govern cytotoxic T lymphocyte activation and tetramer binding properties B Laugel, HA van den Berg, E Gostick, DK Cole, L Wooldridge, J Boulter, ... Journal of Biological Chemistry 282 (33), 23799-23810, 2007 | 274 | 2007 |
| Tricks with tetramers: how to get the most from multimeric peptide–MHC L Wooldridge, A Lissina, DK Cole, HA Van Den Berg, DA Price, AK Sewell Immunology 126 (2), 147-164, 2009 | 239 | 2009 |
| Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes AM Bulek, DK Cole, A Skowera, G Dolton, S Gras, F Madura, A Fuller, ... Nature immunology 13 (3), 283-289, 2012 | 212 | 2012 |
| Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface L Wooldridge, HA van den Berg, M Glick, E Gostick, B Laugel, ... Journal of Biological Chemistry 280 (30), 27491-27501, 2005 | 209 | 2005 |
| Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers A Lissina, K Ladell, A Skowera, M Clement, E Edwards, R Seggewiss, ... Journal of immunological methods 340 (1), 11-24, 2009 | 181 | 2009 |
| Profound inhibition of antigen-specific T-cell effector functions by dasatinib R Weichsel, C Dix, L Wooldridge, M Clement, A Fenton-May, AK Sewell, ... Clinical Cancer Research 14 (8), 2484-2491, 2008 | 175 | 2008 |
| Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity DK Cole, AM Bulek, G Dolton, AJ Schauenberg, B Szomolay, W Rittase, ... The Journal of clinical investigation 126 (6), 2191-2204, 2016 | 158 | 2016 |
| Modification of MHC anchor residues generates heteroclitic peptides that alter TCR binding and T cell recognition DK Cole, ESJ Edwards, KK Wynn, M Clement, JJ Miles, K Ladell, ... The Journal of Immunology 185 (4), 2600-2610, 2010 | 157 | 2010 |
| Escape from highly effective public CD8+ T-cell clonotypes by HIV MC Iglesias, JR Almeida, S Fastenackels, DJ van Bockel, M Hashimoto, ... Blood, The Journal of the American Society of Hematology 118 (8), 2138-2149, 2011 | 131 | 2011 |
| Peptide length determines the outcome of TCR/peptide-MHCI engagement J Ekeruche-Makinde, JJ Miles, HA Van Den Berg, A Skowera, DK Cole, ... Blood, The Journal of the American Society of Hematology 121 (7), 1112-1123, 2013 | 114 | 2013 |
| High avidity antigen-specific CTL identified by CD8-independent tetramer staining EML Choi, JL Chen, L Wooldridge, M Salio, A Lissina, N Lissin, ... The Journal of Immunology 171 (10), 5116-5123, 2003 | 108 | 2003 |
| The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities SL Hutchinson, L Wooldridge, S Tafuro, B Laugel, M Glick, JM Boulter, ... Journal of Biological Chemistry 278 (27), 24285-24293, 2003 | 105 | 2003 |
| Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection JJ Miles, AM Bulek, DK Cole, E Gostick, AJA Schauenburg, G Dolton, ... PLoS pathogens 6 (11), e1001198, 2010 | 103 | 2010 |
| CD8 controls T cell cross-reactivity L Wooldridge, B Laugel, J Ekeruche, M Clement, HA van den Berg, ... The Journal of Immunology 185 (8), 4625-4632, 2010 | 103 | 2010 |
| Enhanced immunogenicity of CTL antigens through mutation of the CD8 binding MHC class I invariant region L Wooldridge, A Lissina, J Vernazza, E Gostick, B Laugel, SL Hutchinson, ... European journal of immunology 37 (5), 1323-1333, 2007 | 87 | 2007 |
| The molecular determinants of CD 8 co‐receptor function DK Cole, B Laugel, M Clement, DA Price, L Wooldridge, AK Sewell Immunology 137 (2), 139-148, 2012 | 81 | 2012 |
| Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity RR Knight, D Kronenberg, M Zhao, GC Huang, M Eichmann, A Bulek, ... Diabetes 62 (1), 205-213, 2013 | 71 | 2013 |
