The Warburg effect 97 years after its discovery RM Pascale, DF Calvisi, MM Simile, CF Feo, F Feo Cancers 12 (10), 2819, 2020 | 195 | 2020 |
Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis M Frau, F Feo, RM Pascale Journal of hepatology 59 (4), 830-841, 2013 | 157 | 2013 |
A functional mammalian target of rapamycin complex 1 signaling is indispensable for c‐Myc‐driven hepatocarcinogenesis P Liu, M Ge, J Hu, X Li, L Che, K Sun, L Cheng, Y Huang, MG Pilo, ... Hepatology 66 (1), 167-181, 2017 | 154 | 2017 |
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans L Che, W Chi, Y Qiao, J Zhang, X Song, Y Liu, L Li, J Jia, MG Pilo, J Wang, ... Gut 69 (1), 177-186, 2020 | 146 | 2020 |
Chemoprevention of Rat Liver Carcinogenesis by S-Adenosyl-l-methionine: A Long-Term Study RM Pascale, V Marras, MM Simile, L Daino, G Pinna, S Bennati, M Carta, ... Cancer research 52 (18), 4979-4986, 1992 | 144 | 1992 |
Dual-specificity phosphatase 1 ubiquitination in extracellular signal-regulated kinase–mediated control of growth in human hepatocellular carcinoma DF Calvisi, F Pinna, F Meloni, S Ladu, R Pellegrino, M Sini, L Daino, ... Cancer research 68 (11), 4192-4200, 2008 | 141 | 2008 |
5′-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication DFC MM Simile, S Banni, E Angioni, G Carta, MR De J. Hepatol. 34 (3), 386-394, 2001 | 137 | 2001 |
Inhibition of Promotion and Persistent Nodule Growth by S-Adenosyl-l-methionine in Rat Liver Carcinogenesis: Role of Remodeling and Apoptosis R Garcea, L Daino, R Pascale, MM Simile, M Puddu, S Frassetto, ... Cancer research 49 (7), 1850-1856, 1989 | 137 | 1989 |
Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans L Li, GM Pilo, X Li, A Cigliano, G Latte, LI Che, C Joseph, M Mela, C Wang, ... Journal of hepatology 64 (2), 333-341, 2016 | 136 | 2016 |
Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine RM Pascale, MM Simile, MR De Miglio, F Feo Alcohol 27 (3), 193-198, 2002 | 135 | 2002 |
Connective tissue growth factor autocriny in human hepatocellular carcinoma: Oncogenic role and regulation by epidermal growth factor receptor/yes‐associated protein–mediated … R Urtasun, MU Latasa, MI Demartis, S Balzani, S Goñi, O Garcia‐Irigoyen, ... Hepatology 54 (6), 2149-2158, 2011 | 131 | 2011 |
SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis DF Calvisi, S Ladu, F Pinna, M Frau, ML Tomasi, M Sini, MM Simile, ... Gastroenterology 137 (5), 1816-1826. e10, 2009 | 128 | 2009 |
Protooncogene methylation and expression in regenerating liver and preneoplastic liver nodules induced in the rat by diethylnitrosamine: effects of variations of S … R Garcea, L Daino, R Pascale, MM Simile, M Puddu, ME Ruggiu, ... Carcinogenesis 10 (7), 1183-1192, 1989 | 118 | 1989 |
Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC DF Calvisi, F Pinna, S Ladu, R Pellegrino, MM Simile, M Frau, ... Gut 58 (5), 679-687, 2009 | 112 | 2009 |
Genetic alterations in liver carcinogenesis: implications for new preventive and therapeutic strategies F Feo, RM Pascale, MM Simile, MR De Miglio, MR Muroni, D Calvisi Critical Reviews™ in Oncogenesis 11 (1), 2000 | 112 | 2000 |
Comparative effects of L-methionine, S-adenosyl-L-methionine and 5’-methylthioadenosine on the growth of preneoplastic lesions and DNA methylation in rat liver during the early … RM Pascale, MM Simile, G Satta, MA Seddaiu, L Daino, G Pinna, ... Anticancer Res 11 (4), 1617-1624, 1991 | 112 | 1991 |
Hepatocellular carcinoma as a complex polygenic disease. Interpretive analysis of recent developments on genetic predisposition F Feo, MR De Miglio, MM Simile, MR Muroni, DF Calvisi, M Frau, ... Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1765 (2), 126-147, 2006 | 108 | 2006 |
Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats FS Falvella, RM Pascale, M Gariboldi, G Manenti, MR De Miglio, ... Carcinogenesis 23 (11), 1933-1936, 2002 | 106 | 2002 |
Prognostic markers and putative therapeutic targets for hepatocellular carcinoma M Frau, F Biasi, F Feo, RM Pascale Molecular aspects of medicine 31 (2), 179-193, 2010 | 100 | 2010 |
Chemoprevention by S-adenosyl-L-methionine of rat liver carcinogenesis initiated by 1,2-dimethylhydrazine and promoted by orotic acid RM Pascale, MM Simile, MRD Miglio, A Nufris, L Daino, MA Seddaiu, ... Carcinogenesis 16 (2), 427-430, 1995 | 100 | 1995 |