Takip et
Souvarish Sarkar
Souvarish Sarkar
University of Rochester Medical Center
urmc.rochester.edu üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Mitochondrial impairment in microglia amplifies NLRP3 inflammasome proinflammatory signaling in cell culture and animal models of Parkinson’s disease
S Sarkar, E Malovic, DS Harishchandra, S Ghaisas, N Panicker, A Charli, ...
npj Parkinson's Disease 3 (1), 30, 2017
2282017
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia
N Panicker, S Sarkar, DS Harischandra, M Neal, TI Kam, H Jin, ...
Journal of Experimental Medicine 216 (6), 1411-1430, 2019
1982019
Fyn kinase regulates microglial neuroinflammatory responses in cell culture and animal models of Parkinson's disease
N Panicker, H Saminathan, H Jin, M Neal, DS Harischandra, R Gordon, ...
Journal of Neuroscience 35 (27), 10058-10077, 2015
1502015
Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein
DS Harischandra, D Rokad, ML Neal, S Ghaisas, S Manne, S Sarkar, ...
Science signaling 12 (572), eaau4543, 2019
1472019
Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes
S Sarkar, E Malovic, DS Harischandra, HA Ngwa, A Ghosh, C Hogan, ...
Neurotoxicology 64, 204-218, 2018
1272018
Manganese activates NLRP3 inflammasome signaling and propagates exosomal release of ASC in microglial cells
S Sarkar, D Rokad, E Malovic, J Luo, DS Harischandra, H Jin, ...
Science Signaling 12 (563), eaat9900, 2019
1172019
Mito-apocynin prevents mitochondrial dysfunction, microglial activation, oxidative damage, and progressive neurodegeneration in MitoPark transgenic mice
M Langley, A Ghosh, A Charli, S Sarkar, M Ay, J Luo, J Zielonka, T Brenza, ...
Antioxidants & redox signaling 27 (14), 1048-1066, 2017
1162017
Prokineticin‐2 promotes chemotaxis and alternative A2 reactivity of astrocytes
M Neal, J Luo, DS Harischandra, R Gordon, S Sarkar, H Jin, ...
Glia 66 (10), 2137-2157, 2018
1032018
Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease
R Gordon, N Singh, V Lawana, A Ghosh, DS Harischandra, H Jin, ...
Neurobiology of disease 93, 96-114, 2016
992016
Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events
N Singh, V Lawana, J Luo, P Phong, A Abdalla, B Palanisamy, D Rokad, ...
Neurobiology of disease 117, 82-113, 2018
952018
Kv1. 3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease
S Sarkar, HM Nguyen, E Malovic, J Luo, M Langley, BN Palanisamy, ...
The Journal of Clinical Investigation 130 (8), 4195-4212, 2020
912020
The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability
E Hallacli, C Kayatekin, S Nazeen, XH Wang, Z Sheinkopf, ...
Cell 185 (12), 2035-2056. e33, 2022
712022
Involvement of c-Abl kinase in microglial activation of NLRP3 inflammasome and impairment in autolysosomal system
V Lawana, N Singh, S Sarkar, A Charli, H Jin, V Anantharam, ...
Journal of Neuroimmune Pharmacology 12, 624-660, 2017
702017
Molecular signatures of neuroinflammation induced by αsynuclein aggregates in microglial cells
S Sarkar, EB Dammer, E Malovic, AL Olsen, SA Raza, T Gao, H Xiao, ...
Frontiers in immunology 11, 33, 2020
652020
Role of the Fyn-PKCδ signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy
S Sharma, S Carlson, S Puttachary, S Sarkar, L Showman, M Putra, ...
Neurobiology of disease 110, 102-121, 2018
592018
α-synuclein impairs autophagosome maturation through abnormal actin stabilization
S Sarkar, AL Olsen, K Sygnecka, KM Lohr, MB Feany
PLoS genetics 17 (2), e1009359, 2021
542021
MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson’s disease
S Ghaisas, MR Langley, BN Palanisamy, S Dutta, K Narayanaswamy, ...
Neurotoxicology 75, 186-199, 2019
382019
Characterization and comparative analysis of a new mouse microglial cell model for studying neuroinflammatory mechanisms during neurotoxic insults
S Sarkar, E Malovic, D Sarda, V Lawana, D Rokad, H Jin, V Anantharam, ...
Neurotoxicology 67, 129-140, 2018
282018
Cobinamide is effective for treatment of hydrogen sulfide–induced neurological sequelae in a mouse model
P Anantharam, EM Whitley, B Mahama, DS Kim, S Sarkar, C Santana, ...
Annals of the New York Academy of Sciences 1408 (1), 61-78, 2017
222017
Rapid and refined CD11b magnetic isolation of primary microglia with enhanced purity and versatility
S Sarkar, E Malovic, B Plante, G Zenitsky, H Jin, V Anantharam, ...
JoVE (Journal of Visualized Experiments), e55364, 2017
222017
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