Leonardo Salmena
Leonardo Salmena
Verified email at utoronto.ca - Homepage
Cited by
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A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language?
L Salmena, L Poliseno, Y Tay, L Kats, PP Pandolfi
Cell 146 (3), 353-358, 2011
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
L Poliseno, L Salmena, J Zhang, B Carver, WJ Haveman, PP Pandolfi
Nature 465 (7301), 1033-1038, 2010
The functions and regulation of the PTEN tumour suppressor
MS Song, L Salmena, PP Pandolfi
Nature reviews Molecular cell biology 13 (5), 283-296, 2012
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
A Carracedo, L Ma, J Teruya-Feldstein, F Rojo, L Salmena, A Alimonti, ...
The Journal of clinical investigation 118 (9), 3065-3074, 2008
Tenets of PTEN tumor suppression
L Salmena, A Carracedo, PP Pandolfi
Cell 133 (3), 403-414, 2008
Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
Y Tay, L Kats, L Salmena, D Weiss, SM Tan, U Ala, F Karreth, L Poliseno, ...
Cell 147 (2), 344-357, 2011
Subtle variations in Pten dose determine cancer susceptibility
A Alimonti, A Carracedo, JG Clohessy, LC Trotman, C Nardella, A Egia, ...
Nature genetics 42 (5), 454-458, 2010
Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
L Salmena, B Lemmers, A Hakem, E Matysiak-Zablocki, K Murakami, ...
Genes & development 17 (7), 883-895, 2003
The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network
MS Song, L Salmena, A Carracedo, A Egia, F Lo-Coco, ...
Nature 455 (7214), 813-817, 2008
Identification of the miR-106b~ 25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation
L Poliseno, L Salmena, L Riccardi, A Fornari, MS Song, RM Hobbs, ...
Science signaling 3 (117), ra29-ra29, 2010
Requirement for caspase-8 in NF-κB activation by antigen receptor
H Su, N Bidère, L Zheng, A Cubre, K Sakai, J Dale, L Salmena, R Hakem, ...
Science 307 (5714), 1465-1468, 2005
Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling
C Gewinner, ZC Wang, A Richardson, J Teruya-Feldstein, ...
Cancer cell 16 (2), 115-125, 2009
High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia
A Gutierrez, T Sanda, R Grebliunaite, A Carracedo, L Salmena, Y Ahn, ...
Blood, The Journal of the American Society of Hematology 114 (3), 647-650, 2009
Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner
MS Song, A Carracedo, L Salmena, SJ Song, A Egia, M Malumbres, ...
Cell 144 (2), 187-199, 2011
Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function
A Papa, L Wan, M Bonora, L Salmena, MS Song, RM Hobbs, A Lunardi, ...
Cell 157 (3), 595-610, 2014
Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity
JP McPherson, L Tamblyn, A Elia, E Migon, A Shehabeldin, ...
The EMBO journal 23 (18), 3677-3688, 2004
Essential role for caspase-8 in Toll-like receptors and NFκB signaling
B Lemmers, L Salmena, N Bidère, H Su, E Matysiak-Zablocki, K Murakami, ...
Journal of Biological Chemistry 282 (10), 7416-7423, 2007
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer
A Lunardi, U Ala, MT Epping, L Salmena, JG Clohessy, KA Webster, ...
Nature genetics 45 (7), 747-755, 2013
Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD
C Berube, LM Boucher, W Ma, A Wakeham, L Salmena, R Hakem, ...
Proceedings of the National Academy of Sciences 102 (40), 14314-14320, 2005
Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events
C Nardella, Z Chen, L Salmena, A Carracedo, A Alimonti, A Egia, ...
Genes & development 22 (16), 2172-2177, 2008
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