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Joshy George
Joshy George
Director, Computational Sciences, Jackson Laboratory for Genomic Medicine, Connecticut
Verified email at jax.org
Title
Cited by
Cited by
Year
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
YH Loh, Q Wu, JL Chew, VB Vega, W Zhang, X Chen, G Bourque, ...
Nature genetics 38 (4), 431-440, 2006
30082006
The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
23382020
Pan-cancer analysis of whole genomes
I TCGA-Consortium
Nature 578 (7793), 82-93, 2020
1672*2020
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
RW Tothill, AV Tinker, J George, R Brown, SB Fox, S Lade, DS Johnson, ...
Clinical cancer research 14 (16), 5198-5208, 2008
15202008
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
LD Miller, J Smeds, J George, VB Vega, L Vergara, A Ploner, Y Pawitan, ...
Proceedings of the National Academy of Sciences 102 (38), 13550-13555, 2005
14892005
Whole–genome characterization of chemoresistant ovarian cancer
AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ...
Nature 521 (7553), 489-494, 2015
14672015
BRCA mutation frequency and patterns of treatment response in BRCA mutation–positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group
K Alsop, S Fereday, C Meldrum, A DeFazio, C Emmanuel, J George, ...
Journal of clinical oncology 30 (21), 2654, 2012
13742012
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ...
Nature 578 (7793), 122-128, 2020
8352020
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
AV Ivshina, J George, O Senko, B Mow, TC Putti, J Smeds, T Lindahl, ...
Cancer research 66 (21), 10292-10301, 2006
8302006
Patterns of somatic structural variation in human cancer genomes
Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ...
Nature 578 (7793), 112-121, 2020
6762020
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
YH Loh, W Zhang, X Chen, J George, HH Ng
Genes & development 21 (20), 2545-2557, 2007
6052007
Whole-genome cartography of estrogen receptor α binding sites
CY Lin, VB Vega, JS Thomsen, T Zhang, SL Kong, M Xie, KP Chiu, ...
PLoS genetics 3 (6), e87, 2007
5402007
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ...
Nature genetics 52 (3), 331-341, 2020
5262020
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ...
Nature 578 (7793), 102-111, 2020
4972020
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
N Lawlor, J George, M Bolisetty, R Kursawe, L Sun, V Sivakamasundari, ...
Genome research 27 (2), 208-222, 2017
4582017
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study
W Sieh, M Köbel, TA Longacre, DD Bowtell, A DeFazio, MT Goodman, ...
The lancet oncology 14 (9), 853-862, 2013
4522013
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene
X Zhang, J George, S Deb, JL Degoutin, EA Takano, SB Fox, DDL Bowtell, ...
Oncogene 30 (25), 2810-2822, 2011
3472011
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas
D Etemadmoghadam, A Defazio, R Beroukhim, C Mermel, J George, ...
Clinical cancer research 15 (4), 1417-1427, 2009
3252009
The landscape of viral associations in human cancers
M Zapatka, I Borozan, DS Brewer, M Iskar, A Grundhoff, M Alawi, N Desai, ...
Nature genetics 52 (3), 320-330, 2020
3182020
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ...
Nature genetics 52 (3), 306-319, 2020
3092020
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