Synthesis, analgesic, and anti-inflammatory activities of [6-(3, 5-dimethyl-4-chloropyrazole-1-yl)-3 (2H)-pyridazinon-2-yl] acetamides M Süküroglu, BÇ Ergün, S ünlü, MF Sahin, E Küpeli, E Yesilada, ... Archives of pharmacal research 28, 509-517, 2005 | 86 | 2005 |
Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP) E Banoglu, B Çalışkan, S Luderer, G Eren, Y Özkan, W Altenhofen, ... Bioorganic & medicinal chemistry 20 (12), 3728-3741, 2012 | 69 | 2012 |
Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl) pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell … ŞC Pirol, B Çalışkan, İ Durmaz, R Atalay, E Banoglu European Journal of Medicinal Chemistry 87, 140-149, 2014 | 67 | 2014 |
Synthesis, antioxidant and antimicrobial evaluation of simple aromatic esters of ferulic acid BÇ Ergün, T Çoban, FK Onurdag, E Banoglu Archives of Pharmacal Research 34, 1251-1261, 2011 | 62 | 2011 |
Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis ZT Gür, B Çalışkan, E Banoglu European Journal of Medicinal Chemistry 153, 34-48, 2018 | 61 | 2018 |
4, 5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP) E Banoglu, E Çelikoğlu, S Völker, A Olgaç, J Gerstmeier, U Garscha, ... European Journal of Medicinal Chemistry 113, 1-10, 2016 | 53 | 2016 |
The novel benzimidazole derivative BRP‐7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5‐lipoxygenase‐activating protein (FLAP) C Pergola, J Gerstmeier, B Mönch, B Çalışkan, S Luderer, C Weinigel, ... British journal of pharmacology 171 (12), 3051-3064, 2014 | 49 | 2014 |
Synthesis and evaluation of analgesic, anti-inflammatory, and anticancer activities of new pyrazole-3 (5)-carboxylic acid derivatives B Çalışkan, A Yılmaz, I Evren, S Menevşe, O Uludag, E Banoglu Medicinal Chemistry Research 22, 782-793, 2013 | 43 | 2013 |
BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly U Garscha, S Voelker, S Pace, J Gerstmeier, B Emini, S Liening, A Rossi, ... Biochemical pharmacology 119, 17-26, 2016 | 40 | 2016 |
Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents B Çalışkan, E Sinoplu, K İbiş, E Akhan Güzelcan, R Çetin Atalay, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 1352-1361, 2018 | 38 | 2018 |
Stable ester and amide conjugates of some NSAIDs as analgesic and antiinflammatory compounds with improved biological activity MO ULUDAĞ, BÇ ERGÜN, DA Alkan, N ERCAN, GY ÖZKAN, ... Turkish Journal of Chemistry 35 (3), 427-439, 2011 | 35 | 2011 |
Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils B Çalışkan, S Luderer, Y Özkan, O Werz, E Banoglu European journal of medicinal chemistry 46 (10), 5021-5033, 2011 | 34 | 2011 |
Synthesis of the amide derivatives of 3-[1-(3-pyridazinyl)-5-phenyl-1H-pyrazole-3-yl] propanoic acids as potential analgesic compounds E Banoğlu, M ŞÜKÜROĞLU, BÇ ERGÜN, SN BAYTAŞ, E Aypar, M ARK Turkish Journal of Chemistry 31 (6), 677-687, 2007 | 34 | 2007 |
Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors B Çalışkan, E Banoglu Expert opinion on drug discovery 8 (1), 49-63, 2013 | 32 | 2013 |
Chromatographic separation and biological evaluation of benzimidazole derivative enantiomers as inhibitors of leukotriene biosynthesis R Sardella, S Levent, F Ianni, B Çalişkan, J Gerstmeier, C Pergola, ... Journal of Pharmaceutical and Biomedical Analysis 89, 88-92, 2014 | 31 | 2014 |
Screening and evaluation of antioxidant activity of some pyridazine derivatives SS Caliskan B, Süküroğlu M, CobanTulay, Banoğlu E Journal of enzyme inhibition and medicinal chemistry 23 (2), 225-229, 2008 | 28* | 2008 |
Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7 ZT Gür, B Çalışkan, UI Garscha, A Olgaç, US Schubert, J Gerstmeier, ... European Journal of Medicinal Chemistry 150, 876-899, 2018 | 26 | 2018 |
Pyrazole derivatives as inhibitors of arachidonic acid-induced platelet aggregation S Levent, B Çalışkan, M Çiftçi, Y Özkan, İ Yenicesu, H Ünver, E Banoglu European Journal of Medicinal Chemistry 64, 42-53, 2013 | 26 | 2013 |
A highly potent TACC3 inhibitor as a novel anticancer drug candidate O Akbulut, D Lengerli, O Saatci, E Duman, UOS Seker, A Isik, A Akyol, ... Molecular cancer therapeutics 19 (6), 1243-1254, 2020 | 22 | 2020 |
Synthesis of amide derivatives of [6-(3, 5-dimethylpyrazol-1-yl)-3 (2H)-pyridazinone-2-yl] acetic acid and their analgesic and anti-inflammatory properties E Banoğlu, Ç Akoğlu, S Ünlü, BÇ Ergün, E Küpeli, E Yeşilada, MF Şahin Arzneimittelforschung 55 (09), 520-527, 2005 | 22 | 2005 |