ilgen mender
ilgen mender
Postdoctoral Researcher of Cell Biology, UTSouthwestern Medical Center
Verified email at
Cited by
Cited by
Regulation of the Human Telomerase Gene TERT by Telomere Position Effect—Over Long Distances (TPE-OLD): Implications for Aging and Cancer
W Kim, AT Ludlow, J Min, JD Robin, G Stadler, I Mender, TP Lai, N Zhang, ...
PLoS biology 14 (12), e2000016, 2016
Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2′-deoxyguanosine
I Mender, S Gryaznov, ZG Dikmen, WE Wright, JW Shay
Cancer discovery 5 (1), 82-95, 2015
A method for measuring the distribution of the shortest telomeres in cells and tissues
TP Lai, N Zhang, J Noh, I Mender, E Tedone, E Huang, WE Wright, ...
Nature communications 8 (1), 1-14, 2017
Telomerase repeated amplification protocol (TRAP)
I Mender, JW Shay
Bio-protocol 5 (22), 2015
Exploiting TERT dependency as a therapeutic strategy for NRAS-mutant melanoma
P Reyes-Uribe, MP Adrianzen-Ruesta, Z Deng, I Echevarria-Vargas, ...
Oncogene 37 (30), 4058-4072, 2018
Imetelstat (a telomerase antagonist) exerts off‑target effects on the cytoskeleton
I Mender, S Senturk, N Ozgunes, K Akcali, D Kletsas, S Gryaznov, A Can, ...
International journal of oncology 42 (5), 1709-1715, 2013
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer
AT Ludlow, MS Wong, JD Robin, K Batten, L Yuan, TP Lai, N Dahlson, ...
Nature communications 9 (1), 1-15, 2018
Telomere restriction fragment (TRF) analysis
I Mender, JW Shay
Bio-protocol 5 (22), 2015
Induced telomere damage to treat telomerase expressing therapy-resistant pediatric brain tumors
S Sengupta, M Sobo, K Lee, SS Kumar, AR White, I Mender, C Fuller, ...
Molecular cancer therapeutics 17 (7), 1504-1514, 2018
Telomerase-mediated strategy for overcoming non–small cell lung cancer targeted therapy and chemotherapy resistance
I Mender, R LaRanger, K Luitel, M Peyton, L Girard, TP Lai, K Batten, ...
Neoplasia 20 (8), 826-837, 2018
Telomere dysfunction induced foci (TIF) analysis
I Mender, JW Shay
Bio-protocol 5 (22), 2015
A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells
I Mender, S Gryaznov, JW Shay
Oncoscience 2 (8), 693, 2015
Induction of telomere dysfunction prolongs disease control of therapy-resistant melanoma
G Zhang, LW Wu, I Mender, M Barzily-Rokni, MR Hammond, O Ope, ...
Clinical Cancer Research 24 (19), 4771-4784, 2018
A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT
GA Hosler, T Davoli, I Mender, B Litzner, J Choi, P Kapur, JW Shay, ...
Journal of cutaneous pathology 42 (2), 108-117, 2015
Human Lung Epithelial Cells Divide> 200 Population Doublings without Engaging a Telomere Maintenance Mechanism
JR Peters-Hall, J Min, E Tedone, S Sho, S Siteni, I Mender, JW Shay
BioRxiv, 474270, 2018
Proliferation of adult human bronchial epithelial cells without a telomere maintenance mechanism for over 200 population doublings
JR Peters‐Hall, J Min, E Tedone, S Sho, S Siteni, I Mender, JW Shay
The FASEB Journal 34 (1), 386-398, 2020
How can I protect my telomeres and slow aging?
ZG Dikmen, I Mender
Turkish Journal of Biochemistry 42 (6), 587-590, 2018
SLC43A3 Is a Biomarker of Sensitivity to the Telomeric DNA Damage Mediator 6-Thio-2′-Deoxyguanosine
I Mender, K Batten, M Peyton, A Vemula, C Cornelius, L Girard, B Gao, ...
Cancer research 80 (5), 929-936, 2020
Treatment of drug resistant proliferative diseases with telomerase mediated telomere altering compounds
J Shay, I Mender, K Batten, C Lander
US Patent App. 15/467,862, 2018
Cancer cell immortality: targeting telomerase
I Mender, Z Gunnur Dikmen, WE Wright, JW Shay
Holland‐Frei Cancer Medicine, 1-9, 2016
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