Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer YA Tang, Y Chen, Y Bao, S Mahara, SMJM Yatim, G Oguz, PL Lee, ... Proceedings of the National Academy of Sciences 115 (26), E5990-E5999, 2018 | 234 | 2018 |
Chromosome 1q21. 3 amplification is a trackable biomarker and actionable target for breast cancer recurrence JY Goh, M Feng, W Wang, G Oguz, SMJM Yatim, PL Lee, Y Bao, TH Lim, ... Nature medicine 23 (11), 1319, 2017 | 142 | 2017 |
Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy S Ma, Y Zhao, WC Lee, LT Ong, PL Lee, Z Jiang, G Oguz, Z Niu, M Liu, ... Nature Communications 13 (1), 1-18, 2022 | 60 | 2022 |
Stromal induction of BRD4 phosphorylation results in chromatin remodeling and BET inhibitor resistance in colorectal cancer W Wang, YA Tang, Q Xiao, WC Lee, B Cheng, Z Niu, G Oguz, M Feng, ... Nature communications 12 (1), 1-17, 2021 | 58 | 2021 |
KDM4B-regulated unfolded protein response as a therapeutic vulnerability in PTEN-deficient breast cancer W Wang, G Oguz, PL Lee, Y Bao, P Wang, MG Terp, HJ Ditzel, Q Yu Journal of Experimental Medicine 215 (11), 2833-2849, 2018 | 37 | 2018 |
EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy Y Bao, G Oguz, WC Lee, PL Lee, K Ghosh, J Li, P Wang, PE Lobie, ... Nature communications 11 (1), 1-17, 2020 | 35 | 2020 |
IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer LT Ong, WC Lee, S Ma, G Oguz, Z Niu, Y Bao, M Yusuf, PL Lee, JY Goh, ... Proceedings of the National Academy of Sciences 119 (31), e2201376119, 2022 | 28 | 2022 |
Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction JL Low, W Du, T Gocha, G Oguz, X Zhang, MW Chen, S Masirevic, ... Iscience 24 (6), 102544, 2021 | 8 | 2021 |
Identification of Breast Cancer Stemness Genes as a Biomarker for Breast Cancer Progression G Oguz PQDT-Global, 2019 | 1 | 2019 |
M4B: A novel method for designing and ordering of the genetic devices S Hashemikhabir, G Ersoy, G Oguz, B Yaldiz, Y Tuncel, G Budak, ... 2012 7th International Symposium on Health Informatics and Bioinformatics …, 2012 | 1 | 2012 |
KDM4B inhibition confers suseptibility to PI3K inhibitor in PTEN-deficient TNBC through overactivating UPR pathway W Wang, G Oguz, PL Lee, SM Yatim, Q Yu MOLECULAR CANCER THERAPEUTICS 17 (1), 2018 | | 2018 |
Abstract B039: KDM4B inhibition confers suseptibility to PI3K inhibitor in PTEN-deficient TNBC through overactivating UPR pathway W Wang, G Oguz, PL Lee, SM Yatim, Q Yu Molecular Cancer Therapeutics 17 (1 Supplement), B039-B039, 2018 | | 2018 |
CHROMOSOME 1q21. 3 AMPLIFICATION IS LINKED TO BREAST CANCER RECURRENCE JY Goh, M Feng, W Wang, G Oguz, SM Yatim, PL Lee CANCER DISCOVERY 7 (11), 1215-1215, 2017 | | 2017 |