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gustavo leone
gustavo leone
Professor of Biochemistry, medical college of wisconsin
Verified email at mcw.edu
Title
Cited by
Cited by
Year
Emerging roles of E2Fs in cancer: an exit from cell cycle control
HZ Chen, SY Tsai, G Leone
Nature reviews cancer 9 (11), 785-797, 2009
10632009
Distinct roles for E2F proteins in cell growth control and apoptosis
J DeGregori, G Leone, A Miron, L Jakoi, JR Nevins
Proceedings of the National Academy of Sciences 94 (14), 7245-7250, 1997
9141997
The E2F1–3 transcription factors are essential for cellular proliferation
L Wu, C Timmers, B Maiti, HI Saavedra, L Sang, GT Chong, F Nuckolls, ...
Nature 414 (6862), 457-462, 2001
7612001
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
S Ishida, E Huang, H Zuzan, R Spang, G Leone, M West, JR Nevins
Molecular and cellular biology 21 (14), 4684-4699, 2001
7262001
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
G Leone, J DeGregori, R Sears, L Jakoi, JR Nevins
Nature 387 (6631), 422-426, 1997
6281997
Pten in stromal fibroblasts suppresses mammary epithelial tumours
AJ Trimboli, CZ Cantemir-Stone, F Li, JA Wallace, A Merchant, N Creasap, ...
Nature 461 (7267), 1084-1091, 2009
6052009
The broken cycle: E2F dysfunction in cancer
LN Kent, G Leone
Nature Reviews Cancer 19 (6), 326-338, 2019
5792019
Ras enhances Myc protein stability
R Sears, G Leone, J DeGregori, JR Nevins
Molecular cell 3 (2), 169-179, 1999
5631999
Direct evidence for epithelial-mesenchymal transitions in breast cancer
AJ Trimboli, K Fukino, A De Bruin, G Wei, L Shen, SM Tanner, N Creasap, ...
Cancer research 68 (3), 937-945, 2008
4842008
E2F3 activity is regulated during the cell cycle and is required for the induction of S phase
G Leone, J DeGregori, Z Yan, L Jakoi, S Ishida, RS Williams, JR Nevins
Genes & development 12 (14), 2120-2130, 1998
4661998
Extra-embryonic function of Rb is essential for embryonic development and viability
L Wu, A De Bruin, HI Saavedra, M Starovic, A Trimboli, Y Yang, J Opavska, ...
Nature 421 (6926), 942-947, 2003
4432003
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
A Bronisz, J Godlewski, JA Wallace, AS Merchant, MO Nowicki, ...
Nature cell biology 14 (2), 159-167, 2012
3272012
Myc requires distinct E2F activities to induce S phase and apoptosis
G Leone, R Sears, E Huang, R Rempel, F Nuckolls, CH Park, ...
Molecular cell 8 (1), 105-113, 2001
3252001
The accumulation of an E2F-p130 transcriptional repressor distinguishes a G0 cell state from a G1 cell state
EJ Smith, G Leone, J DeGregori, L Jakoi, JR Nevins
Molecular and cellular biology, 1996
3231996
Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells
Z Yan, J DeGregori, R Shohet, G Leone, B Stillman, JR Nevins, ...
Proceedings of the National Academy of Sciences 95 (7), 3603-3608, 1998
3191998
Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation
A De Bruin, B Maiti, L Jakoi, C Timmers, R Buerki, G Leone
Journal of Biological Chemistry 278 (43), 42041-42049, 2003
3102003
E2F-1 accumulation bypasses a G1 arrest resulting from the inhibition of G1 cyclin-dependent kinase activity.
J DeGregori, G Leone, K Ohtani, A Miron, JR Nevins
Genes & development 9 (23), 2873-2887, 1995
2931995
E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells
JL Chong, PL Wenzel, MT Sáenz-Robles, V Nair, A Ferrey, JP Hagan, ...
Nature 462 (7275), 930-934, 2009
2822009
Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer
Z Qamri, A Preet, MW Nasser, CE Bass, G Leone, SH Barsky, RK Ganju
Molecular cancer therapeutics 8 (11), 3117-3129, 2009
2712009
Role of the Rb/E2F pathway in cell growth control
JR Nevins, G Leone, J DeGregori, L Jakoi
Journal of cellular physiology 173 (2), 233-236, 1997
2691997
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