Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 580 | 2020 |
Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors B Raveh, N London, L Zimmerman, O Schueler-Furman PloS one 6 (4), e18934, 2011 | 307 | 2011 |
Structure-based identification of HDAC8 non-histone substrates N Alam, L Zimmerman, NA Wolfson, CG Joseph, CA Fierke, ... Structure 24 (3), 458-468, 2016 | 57 | 2016 |
A novel system for functional determination of variants of uncertain significance using deep convolutional neural networks L Zimmerman, O Zelichov, A Aizenmann, Z Barbash, M Vidne, G Tarcic Scientific Reports 10 (1), 4192, 2020 | 5 | 2020 |
A systematic analysis of BRAF mutations and their sensitivity to different BRAF inhibitors Z Barbash, D Haham, L Hafzadi, R Zipor, S Barth, A Aizenman, ... Cancer Research 80 (16_Supplement), 1092-1092, 2020 | 1 | 2020 |
Pross optimized enzymes L Zimmerman, D Baran US Patent App. 16/629,372, 2020 | 1 | 2020 |
Project plan generation from an information architecture model BP Byrne, H Marchant, L Zimmerman US Patent 10,346,776, 2019 | 1 | 2019 |
Context-dependent design of induced-fit enzymes using deep learning generates well-expressed, thermally stable and active enzymes L Zimmerman, N Alon, I Levin, A Koganitsky, N Shpigel, C Brestel, ... Proceedings of the National Academy of Sciences 121 (11), e2313809121, 2024 | | 2024 |
Performance upgrade of a microbial explosives’ sensor strain by screening a high throughput saturation library of a transcriptional regulator L David, E Shpigel, I Levin, S Moshe, L Zimmerman, S Dadon-Simanowitz, ... Computational and Structural Biotechnology Journal 21, 4252-4260, 2023 | | 2023 |
System and method for generating antibody libraries L Zimmerman, D Baran US Patent App. 17/163,989, 2021 | | 2021 |
Computational pipeline for antibody modeling and design D Baran, L Zimmerman US Patent 11,127,483, 2021 | | 2021 |
Pross optimized enzymes L Zimmerman, D Baran US Patent App. 16/646,298, 2020 | | 2020 |
Anti-vegf antibody D Baran, L Zimmerman US Patent App. 16/646,093, 2020 | | 2020 |
Computational affinity maturation of antibody libraries using sequence enumeration L Zimmerman US Patent App. 16/656,113, 2020 | | 2020 |
Anti-pd-1 scfvs D Baran, L Zimmerman US Patent App. 16/242,417, 2019 | | 2019 |
Accurate prediction of the signaling pathway activity elicited by variants of uncertain significance (VUS) and their drug sensitivity using deep convolutional neural networks … L Zimmerman, A Aizenman, Y Daitsh, Z Barbash, G Tarcic, M Vidne Cancer Research 79 (13_Supplement), 2447-2447, 2019 | | 2019 |
Project plan generation from an information architecture model BP Byrne, H Marchant, L Zimmerman US Patent 10,318,906, 2019 | | 2019 |
Mapping the activation landscape of the MAPK\ERK pathway for variants of unknown significance (VUS) using convolutional neural networks (CNN). G Tarcic, L Zimmerman, A Aizenman, Z Barbash, O Zelichov, M Vidne Journal of Clinical Oncology 37 (15_suppl), e14615-e14615, 2019 | | 2019 |
System and method for generating antibody libraries L Zimmerman, D Baran US Patent App. 15/863,927, 2018 | | 2018 |
Computational methods for designing polypeptide libraries L Zimmerman US Patent App. 15/685,611, 2018 | | 2018 |