| Catch-bond mechanism of the bacterial adhesin FimH MM Sauer, RP Jakob, J Eras, S Baday, D Eriþ, G Navarra, S Berneche, ... Nature communications 7 (1), 10738, 2016 | 253 | 2016 |
| The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase H Kaur, RP Jakob, JK Marzinek, R Green, Y Imai, JR Bolla, E Agustoni, ... Nature 593 (7857), 125-129, 2021 | 172 | 2021 |
| The structural basis of autotransporter translocation by TamA F Gruss, F Zähringer, RP Jakob, BM Burmann, S Hiller, T Maier Nature structural & molecular biology 20 (11), 1318-1320, 2013 | 141 | 2013 |
| Increased Folding Stability of TEM-1 β-Lactamase by In Vitro Selection I Kather, RP Jakob, H Dobbek, FX Schmid Journal of molecular biology 383 (1), 238-251, 2008 | 109 | 2008 |
| FimH antagonists: bioisosteres to improve the in vitro and in vivo PK/PD profile S Kleeb, L Pang, K Mayer, D Eris, A Sigl, RC Preston, P Zihlmann, ... American Chemical Society, 2015 | 107 | 2015 |
| Long-lived T follicular helper cells retain plasticity and help sustain humoral immunity M Künzli, D Schreiner, TC Pereboom, N Swarnalekha, LC Litzler, ... Science immunology 5 (45), eaay5552, 2020 | 106 | 2020 |
| Binding of the bacterial adhesin FimH to its natural, multivalent high-mannose type glycan targets MM Sauer, RP Jakob, T Luber, F Canonica, G Navarra, B Ernst, ... Journal of the American Chemical Society 141 (2), 936-944, 2018 | 103 | 2018 |
| Quercetinase QueD of Streptomyces sp. FLA, a Monocupin Dioxygenase with a Preference for Nickel and Cobalt H Merkens, R Kappl, RP Jakob, FX Schmid, S Fetzner Biochemistry 47 (46), 12185-12196, 2008 | 95 | 2008 |
| Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases DA Herbst, RP Jakob, F Zähringer, T Maier Nature 531 (7595), 533-537, 2016 | 90 | 2016 |
| Chaperone domains convert prolyl isomerases into generic catalysts of protein folding RP Jakob, G Zoldák, T Aumüller, FX Schmid Proceedings of the National Academy of Sciences 106 (48), 20282-20287, 2009 | 81 | 2009 |
| E-selectin ligand complexes adopt an extended high-affinity conformation RC Preston, RP Jakob, FPC Binder, CP Sager, B Ernst, T Maier Journal of molecular cell biology 8 (1), 62-72, 2016 | 77 | 2016 |
| Computational identification of a systemic antibiotic for gram-negative bacteria RD Miller, A Iinishi, SM Modaresi, BK Yoo, TD Curtis, PJ Lariviere, L Liang, ... Nature microbiology 7 (10), 1661-1672, 2022 | 75 | 2022 |
| Xenobiotic Reductase A in the Degradation of Quinoline by Pseudomonas putida 86: Physiological Function, Structure and Mechanism of 8-Hydroxycoumarin … JJ Griese, RP Jakob, S Schwarzinger, H Dobbek Journal of molecular biology 361 (1), 140-152, 2006 | 75 | 2006 |
| The dynamic mechanism of 4E-BP1 recognition and phosphorylation by mTORC1 R Böhm, S Imseng, RP Jakob, MN Hall, T Maier, S Hiller Molecular cell 81 (11), 2403-2416. e5, 2021 | 62 | 2021 |
| The structural organization of substrate loading in iterative polyketide synthases DA Herbst, CR Huitt-Roehl, RP Jakob, JM Kravetz, PA Storm, JR Alley, ... Nature chemical biology 14 (5), 474-479, 2018 | 61 | 2018 |
| The tyrosine gate of the bacterial lectin FimH: a conformational analysis by NMR spectroscopy and X‐ray crystallography B Fiege, S Rabbani, RC Preston, RP Jakob, P Zihlmann, O Schwardt, ... ChemBioChem 16 (8), 1235-1246, 2015 | 54 | 2015 |
| The prolyl isomerase domain of PpiD from Escherichia coli shows a parvulin fold but is devoid of catalytic activity U Weininger, RP Jakob, M Kovermann, J Balbach, FX Schmid Protein Science 19 (1), 6-18, 2010 | 53 | 2010 |
| Dimeric structure of the bacterial extracellular foldase PrsA RP Jakob, JR Koch, BM Burmann, PAM Schmidpeter, M Hunkeler, ... Journal of Biological Chemistry 290 (6), 3278-3292, 2015 | 51 | 2015 |
| Energetic coupling between native-state prolyl isomerization and conformational protein folding RP Jakob, FX Schmid Journal of molecular biology 377 (5), 1560-1575, 2008 | 50 | 2008 |
| Evolutionary origins of the multienzyme architecture of giant fungal fatty acid synthase HST Bukhari, RP Jakob, T Maier Structure 22 (12), 1775-1785, 2014 | 48 | 2014 |
