Takip et
Yuan Wang
Yuan Wang
UCB Biosciences, Bedford, MA, USA
ucb.com üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
Using information from historical high-throughput screens to predict active compounds
S Riniker, Y Wang, JL Jenkins, GA Landrum
Journal of chemical information and modeling 54 (7), 1880-1891, 2014
892014
Size uniformity of animal cells is actively maintained by a p38 MAPK-dependent regulation of G1-length
S Liu, MB Ginzberg, N Patel, M Hild, B Leung, Z Li, YC Chen, N Chang, ...
eLife 7, e26947, 2018
812018
Cheminformatics Tools for Analyzing and Designing Optimized Small-Molecule Collections and Libraries
N Moret, NA Clark, M Hafner, Y Wang, E Lounkine, M Medvedovic, ...
Cell chemical biology 26 (5), 765-777. e3, 2019
642019
Cheminformatics tools for analyzing and designing optimized Small-Molecule collections and libraries
N Moret, NA Clark, M Hafner, Y Wang, E Lounkine, M Medvedovic, ...
Cell chemical biology 26 (5), 765-777. e3, 2019
642019
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
NT Ross, F Lohmann, S Carbonneau, A Fazal, WA Weihofen, S Gleim, ...
Nature Chemical Biology 16 (1), 50-59, 2020
612020
Evidence-based and quantitative prioritization of tool compounds in phenotypic drug discovery
Y Wang, A Cornett, FJ King, Y Mao, F Nigsch, CG Paris, G McAllister, ...
Cell chemical biology 23 (7), 862-874, 2016
592016
Systematic chemogenetic library assembly
SM Canham, Y Wang, A Cornett, DS Auld, DK Baeschlin, M Patoor, ...
Cell chemical biology 27 (9), 1124-1129, 2020
402020
Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
C Tan, MB Ginzberg, R Webster, S Iyengar, S Liu, D Papadopoli, ...
Developmental Cell 56 (12), 1756-1769. e7, 2021
382021
Balancing the influence of molecular complexity on fingerprint similarity searching
Y Wang, J Bajorath
Journal of chemical information and modeling 48 (1), 75-84, 2008
332008
Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy
JM Cruz, N Hupper, LS Wilson, JB Concannon, Y Wang, B Oberhauser, ...
Journal of Biological Chemistry 293 (30), 11837-11849, 2018
302018
Apparent asymmetry in fingerprint similarity searching is a direct consequence of differences in bit densities and molecular size
Y Wang, H Eckert, J Bajorath
ChemMedChem 2 (7), 1037-1042, 2007
292007
Bit silencing in fingerprints enables the derivation of compound class-directed similarity metrics
Y Wang, J Bajorath
Journal of chemical information and modeling 48 (9), 1754-1759, 2008
272008
A High Content Screen in Macrophages Identifies Small Molecule Modulators of STING-IRF3 and NFkB Signaling
PD Koch, HR Miller, G Yu, JA Tallarico, PK Sorger, Y Wang, Y Feng, ...
ACS chemical biology 13 (4), 1066-1081, 2018
192018
Shannon entropy-based fingerprint similarity search strategy
Y Wang, H Geppert, J Bajorath
Journal of chemical information and modeling 49 (7), 1687-1691, 2009
192009
Development of a compound class-directed similarity coefficient that accounts for molecular complexity effects in fingerprint searching
Y Wang, J Bajorath
Journal of chemical information and modeling 49 (6), 1369-1376, 2009
192009
Advanced fingerprint methods for similarity searching: balancing molecular complexity effects
Y Wang, J Bajorath
Combinatorial chemistry & high throughput screening 13 (3), 220-228, 2010
182010
Random reduction in fingerprint bit density improves compound recall in search calculations using complex reference molecules
Y Wang, H Geppert, J Bajorath
Chemical biology & drug design 71 (6), 511-517, 2008
132008
Previously Uncharacterized Vacuolar-type ATPase Binding Site Discovered from Structurally Similar Compounds with Distinct Mechanisms of Action
AC Wang, HT Pham, JM Lipps, SM Brittain, E Harrington, Y Wang, FJ King, ...
ACS chemical biology 14 (1), 20-26, 2018
72018
Quantitative prioritization of tool compounds for phenotypic screening
Y Wang, JL Jenkins
Phenotypic Screening: Methods and Protocols, 195-206, 2018
42018
Activation of human STING by a molecular glue-like compound
J Li, SM Canham, H Wu, M Henault, L Chen, G Liu, Y Chen, G Yu, ...
Nature chemical biology, 1-8, 2023
32023
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