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Antony Rosen
Antony Rosen
Mary Betty Stevens Professor of Medicine, Johns Hopkins
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.
LA Casciola-Rosen, G Anhalt, A Rosen
The Journal of experimental medicine 179 (4), 1317-1330, 1994
20871994
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.
L Casciola-Rosen, DW Nicholson, T Chong, KR Rowan, NA Thornberry, ...
The Journal of experimental medicine 183 (5), 1957-1964, 1996
7841996
Autoantibodies against 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase in patients with statin‐associated autoimmune myopathy
AL Mammen, T Chung, L Christopher‐Stine, P Rosen, A Rosen, ...
Arthritis & Rheumatism 63 (3), 713-721, 2011
7402011
Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity
L Casciola-Rosen, F Andrade, D Ulanet, WB Wong, A Rosen
The Journal of experimental medicine 190 (6), 815-826, 1999
6491999
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus.
L Casciola-Rosen, A Rosen, M Petri, M Schlissel
Proceedings of the National Academy of Sciences 93 (4), 1624-1629, 1996
5811996
Aggregatibacter actinomycetemcomitans–induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis
MF Konig, L Abusleme, J Reinholdt, RJ Palmer, RP Teles, K Sampson, ...
Science translational medicine 8 (369), 369ra176-369ra176, 2016
5732016
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset
R Goldbach-Mansky, J Lee, A McCoy, J Hoxworth, C Yarboro, JS Smolen, ...
Arthritis Research & Therapy 2, 1-8, 2000
5592000
The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): a retrospective study
D Fiorentino, L Chung, J Zwerner, A Rosen, L Casciola-Rosen
Journal of the American Academy of Dermatology 65 (1), 25-34, 2011
5582011
DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis.
LA Casciola-Rosen, GJ Anhalt, A Rosen
The Journal of experimental medicine 182 (6), 1625-1634, 1995
5571995
The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling
M Mancini, DW Nicholson, S Roy, NA Thornberry, EP Peterson, ...
The Journal of cell biology 140 (6), 1485-1495, 1998
5561998
Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death.
LA Casciola-Rosen, DK Miller, GJ Anhalt, A Rosen
Journal of Biological Chemistry 269 (49), 30757-30760, 1994
5371994
Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis
M Mancini, CE Machamer, S Roy, DW Nicholson, NA Thornberry, ...
The Journal of cell biology 149 (3), 603-612, 2000
4952000
Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane
M Thelen, A Rosen, AC Nairn, A Aderem
Nature 351 (6324), 320-322, 1991
4761991
Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis
F Andrade, S Roy, D Nicholson, N Thornberry, A Rosen, ...
Immunity 8 (4), 451-460, 1998
4721998
Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy
L Casciola-Rosen, K Nagaraju, P Plotz, K Wang, S Levine, E Gabrielson, ...
The Journal of experimental medicine 201 (4), 591-601, 2005
4542005
Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease
A Rosen, L Casciola-Rosen
Cell Death & Differentiation 6 (1), 6-12, 1999
4511999
Association of the autoimmune disease scleroderma with an immunologic response to cancer
CG Joseph, E Darrah, AA Shah, AD Skora, LA Casciola-Rosen, ...
Science 343 (6167), 152-157, 2014
4382014
Most patients with cancer‐associated dermatomyositis have antibodies to nuclear matrix protein NXP‐2 or transcription intermediary factor 1γ
DF Fiorentino, LS Chung, L Christopher‐Stine, L Zaba, S Li, AL Mammen, ...
Arthritis & Rheumatism 65 (11), 2954-2962, 2013
4052013
Hsp60 accelerates the maturation of pro‐caspase‐3 by upstream activator proteases during apoptosis
S Xanthoudakis, S Roy, D Rasper, T Hennessey, Y Aubin, R Cassady, ...
The EMBO journal, 1999
3851999
Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction
K Nagaraju, L Casciola‐Rosen, I Lundberg, R Rawat, S Cutting, ...
Arthritis & Rheumatism 52 (6), 1824-1835, 2005
3642005
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