Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes. LA Casciola-Rosen, G Anhalt, A Rosen The Journal of experimental medicine 179 (4), 1317-1330, 1994 | 2087 | 1994 |
Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. L Casciola-Rosen, DW Nicholson, T Chong, KR Rowan, NA Thornberry, ... The Journal of experimental medicine 183 (5), 1957-1964, 1996 | 784 | 1996 |
Autoantibodies against 3‐hydroxy‐3‐methylglutaryl‐coenzyme A reductase in patients with statin‐associated autoimmune myopathy AL Mammen, T Chung, L Christopher‐Stine, P Rosen, A Rosen, ... Arthritis & Rheumatism 63 (3), 713-721, 2011 | 740 | 2011 |
Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity L Casciola-Rosen, F Andrade, D Ulanet, WB Wong, A Rosen The Journal of experimental medicine 190 (6), 815-826, 1999 | 649 | 1999 |
Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: implications for coagulation events and antigenic spread in systemic lupus erythematosus. L Casciola-Rosen, A Rosen, M Petri, M Schlissel Proceedings of the National Academy of Sciences 93 (4), 1624-1629, 1996 | 581 | 1996 |
Aggregatibacter actinomycetemcomitans–induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis MF Konig, L Abusleme, J Reinholdt, RJ Palmer, RP Teles, K Sampson, ... Science translational medicine 8 (369), 369ra176-369ra176, 2016 | 573 | 2016 |
Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset R Goldbach-Mansky, J Lee, A McCoy, J Hoxworth, C Yarboro, JS Smolen, ... Arthritis Research & Therapy 2, 1-8, 2000 | 559 | 2000 |
The mucocutaneous and systemic phenotype of dermatomyositis patients with antibodies to MDA5 (CADM-140): a retrospective study D Fiorentino, L Chung, J Zwerner, A Rosen, L Casciola-Rosen Journal of the American Academy of Dermatology 65 (1), 25-34, 2011 | 558 | 2011 |
DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis. LA Casciola-Rosen, GJ Anhalt, A Rosen The Journal of experimental medicine 182 (6), 1625-1634, 1995 | 557 | 1995 |
The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling M Mancini, DW Nicholson, S Roy, NA Thornberry, EP Peterson, ... The Journal of cell biology 140 (6), 1485-1495, 1998 | 556 | 1998 |
Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death. LA Casciola-Rosen, DK Miller, GJ Anhalt, A Rosen Journal of Biological Chemistry 269 (49), 30757-30760, 1994 | 537 | 1994 |
Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis M Mancini, CE Machamer, S Roy, DW Nicholson, NA Thornberry, ... The Journal of cell biology 149 (3), 603-612, 2000 | 495 | 2000 |
Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane M Thelen, A Rosen, AC Nairn, A Aderem Nature 351 (6324), 320-322, 1991 | 476 | 1991 |
Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis F Andrade, S Roy, D Nicholson, N Thornberry, A Rosen, ... Immunity 8 (4), 451-460, 1998 | 472 | 1998 |
Enhanced autoantigen expression in regenerating muscle cells in idiopathic inflammatory myopathy L Casciola-Rosen, K Nagaraju, P Plotz, K Wang, S Levine, E Gabrielson, ... The Journal of experimental medicine 201 (4), 591-601, 2005 | 454 | 2005 |
Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune disease A Rosen, L Casciola-Rosen Cell Death & Differentiation 6 (1), 6-12, 1999 | 451 | 1999 |
Association of the autoimmune disease scleroderma with an immunologic response to cancer CG Joseph, E Darrah, AA Shah, AD Skora, LA Casciola-Rosen, ... Science 343 (6167), 152-157, 2014 | 438 | 2014 |
Most patients with cancer‐associated dermatomyositis have antibodies to nuclear matrix protein NXP‐2 or transcription intermediary factor 1γ DF Fiorentino, LS Chung, L Christopher‐Stine, L Zaba, S Li, AL Mammen, ... Arthritis & Rheumatism 65 (11), 2954-2962, 2013 | 405 | 2013 |
Hsp60 accelerates the maturation of pro‐caspase‐3 by upstream activator proteases during apoptosis S Xanthoudakis, S Roy, D Rasper, T Hennessey, Y Aubin, R Cassady, ... The EMBO journal, 1999 | 385 | 1999 |
Activation of the endoplasmic reticulum stress response in autoimmune myositis: potential role in muscle fiber damage and dysfunction K Nagaraju, L Casciola‐Rosen, I Lundberg, R Rawat, S Cutting, ... Arthritis & Rheumatism 52 (6), 1824-1835, 2005 | 364 | 2005 |