Recent developments in hydantoin chemistry. A review M Meusel, M Gütschow Organic preparations and procedures international 36 (5), 391-443, 2004 | 309 | 2004 |
Degradation of Quercetin and Luteolin byEubacterium ramulus A Braune, M Gütschow, W Engst, M Blaut Applied and environmental microbiology 67 (12), 5558-5567, 2001 | 258 | 2001 |
Conversion of daidzein and genistein by an anaerobic bacterium newly isolated from the mouse intestine A Matthies, T Clavel, M Gütschow, W Engst, D Haller, M Blaut, A Braune Applied and environmental microbiology 74 (15), 4847-4852, 2008 | 177 | 2008 |
Calcium-sensing receptors signal constitutive macropinocytosis and facilitate the uptake of NOD2 ligands in macrophages J Canton, D Schlam, C Breuer, M Gütschow, M Glogauer, S Grinstein Nature communications 7 (1), 11284, 2016 | 145 | 2016 |
Homo-PROTACs for the chemical knockdown of cereblon C Steinebach, S Lindner, ND Udeshi, DC Mani, H Kehm, S Köpff, ... ACS chemical biology 13 (9), 2771-2782, 2018 | 134 | 2018 |
Dysfunction of the key ferroptosis-surveilling systems hypersensitizes mice to tubular necrosis during acute kidney injury W Tonnus, C Meyer, C Steinebach, A Belavgeni, A von Mässenhausen, ... Nature communications 12 (1), 4402, 2021 | 132 | 2021 |
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice D Meynard, V Vaja, CC Sun, E Corradini, S Chen, C López-Otín, ... Blood, The Journal of the American Society of Hematology 118 (3), 747-756, 2011 | 132 | 2011 |
Interaction of papain-like cysteine proteases with dipeptide-derived nitriles R Löser, K Schilling, E Dimmig, M Gütschow Journal of medicinal chemistry 48 (24), 7688-7707, 2005 | 132 | 2005 |
2-(Diethylamino) thieno [1, 3] oxazin-4-ones as stable inhibitors of human leukocyte elastase M Gütschow, L Kuerschner, U Neumann, M Pietsch, R Löser, N Koglin, ... Journal of medicinal chemistry 42 (26), 5437-5447, 1999 | 131 | 1999 |
Development of nitrile-based peptidic inhibitors of cysteine cathepsins M Frizler, M Stirnberg, MT Sisay, M Gutschow Current topics in medicinal chemistry 10 (3), 294-322, 2010 | 126 | 2010 |
Synthesis of tricyclic 1, 3-oxazin-4-ones and kinetic analysis of cholesterol esterase and acetylcholinesterase inhibition M Pietsch, M Gütschow Journal of medicinal chemistry 48 (26), 8270-8288, 2005 | 124 | 2005 |
Antimicrobial phenalenone derivatives from the marine-derived fungus Coniothyrium cereale MF Elsebai, S Kehraus, U Lindequist, F Sasse, S Shaaban, M Gütschow, ... Organic & Biomolecular Chemistry 9 (3), 802-808, 2011 | 121 | 2011 |
Analogs of thalidomide as potential angiogenesis inhibitors WD Figg, K Eger, U Teubert, M Weiss, M Guetschow, T Hecker, ... US Patent 7,320,991, 2008 | 119 | 2008 |
E3 ligase ligands in successful PROTACs: an overview of syntheses and linker attachment points A Bricelj, C Steinebach, R Kuchta, M Gütschow, I Sosič Frontiers in chemistry 9, 707317, 2021 | 115 | 2021 |
Antiangiogenic activity of N-substituted and tetrafluorinated thalidomide analogues SSW Ng, M Gütschow, M Weiss, S Hauschildt, U Teubert, TK Hecker, ... Cancer research 63 (12), 3189-3194, 2003 | 110 | 2003 |
Targeting the main protease of SARS‐CoV‐2: from the establishment of high throughput screening to the design of tailored inhibitors J Breidenbach, C Lemke, T Pillaiyar, L Schäkel, G Al Hamwi, M Diett, ... Angewandte Chemie International Edition 60 (18), 10423-10429, 2021 | 106 | 2021 |
3CL protease inhibitors with an electrophilic arylketone moiety as anti-SARS-CoV-2 agents S Konno, K Kobayashi, M Senda, Y Funai, Y Seki, I Tamai, L Schäkel, ... Journal of Medicinal Chemistry 65 (4), 2926-2939, 2021 | 102 | 2021 |
Structural optimization of azadipeptide nitriles strongly increases association rates and allows the development of selective cathepsin inhibitors M Frizler, F Lohr, N Furtmann, J Kläs, M Gütschow Journal of medicinal chemistry 54 (1), 396-400, 2011 | 98 | 2011 |
A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer S Blättermann, L Peters, PA Ottersbach, A Bock, V Konya, CD Weaver, ... Nature chemical biology 8 (7), 631-638, 2012 | 95 | 2012 |
Dual Targeting of Adenosine A2A Receptors and Monoamine Oxidase B by 4H-3,1-Benzothiazin-4-ones A Stößel, M Schlenk, S Hinz, P Küppers, J Heer, M Gütschow, ... Journal of medicinal chemistry 56 (11), 4580-4596, 2013 | 93 | 2013 |