Takip et
Eric Arnoult
Eric Arnoult
Ferring Research Institute
ferring.com üzerinde doğrulanmış e-posta adresine sahip
Başlık
Alıntı yapanlar
Alıntı yapanlar
Yıl
The challenge of new drug discovery for tuberculosis
A Koul, E Arnoult, N Lounis, J Guillemont, K Andries
Nature 469 (7331), 483-490, 2011
13172011
Preliminary screening of some tropical plants for anti-tyrosinase activity
N Baurin, E Arnoult, T Scior, QT Do, P Bernard
Journal of ethnopharmacology 82 (2-3), 155-158, 2002
2542002
Molecular mechanism of respiratory syncytial virus fusion inhibitors
MB Battles, JP Langedijk, P Furmanova-Hollenstein, ...
Nature chemical biology 12 (2), 87-93, 2016
1542016
2D QSAR consensus prediction for high-throughput virtual screening. An application to COX-2 inhibition modeling and screening of the NCI database
N Baurin, JC Mozziconacci, E Arnoult, P Chavatte, C Marot, L Morin-Allory
Journal of chemical information and computer sciences 44 (1), 276-285, 2004
1252004
Difluoromethylbenzoxazole pyrimidine thioether derivatives: a novel class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors
J Boyer, E Arnoult, M Médebielle, J Guillemont, J Unge, D Jochmans
Journal of medicinal chemistry 54 (23), 7974-7985, 2011
1022011
Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein
D Roymans, HL De Bondt, E Arnoult, P Geluykens, T Gevers, ...
Proceedings of the National Academy of Sciences 107 (1), 308-313, 2010
1022010
Therapeutic efficacy of a respiratory syncytial virus fusion inhibitor
D Roymans, SS Alnajjar, MB Battles, P Sitthicharoenchai, ...
Nature communications 8 (1), 167, 2017
742017
Optimization and validation of a docking-scoring protocol; application to virtual screening for COX-2 inhibitors
JC Mozziconacci, E Arnoult, P Bernard, QT Do, C Marot, L Morin-Allory
Journal of medicinal chemistry 48 (4), 1055-1068, 2005
682005
Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure− property relationship
JF Bonfanti, F Doublet, J Fortin, J Lacrampe, J Guillemont, P Muller, ...
Journal of medicinal chemistry 50 (19), 4572-4584, 2007
592007
A long-acting PYY3–36 analog mediates robust anorectic efficacy with minimal emesis in nonhuman primates
SM Rangwala, K D’Aquino, YM Zhang, L Bader, W Edwards, S Zheng, ...
Cell metabolism 29 (4), 837-843. e5, 2019
462019
Macrocyclic purines for the treatment of viral infections
JF Bonfanti, JMC Fortin, P Muller, FMM Doublet, PJMB Raboisson, ...
US Patent 10,280,180, 2019
342019
Novel pyrimidine toll-like receptor 7 and 8 dual agonists to treat hepatitis B virus
D McGowan, F Herschke, F Pauwels, B Stoops, S Last, S Pieters, ...
Journal of Medicinal Chemistry 59 (17), 7936-7949, 2016
342016
Macrocyclic deaza-purinones for the treatment of viral infections
JF Bonfanti, JMC Fortin, P Muller, FMM Doublet, PJMB Raboisson, ...
US Patent 10,266,543, 2019
302019
HIV-1(Lai) genomic RNA: combined used of NMR and molecular dynamics simulation for studying the structure and internal dynamics of a mutated SL1 hairpin.
LG Kieken F , Arnoult E , Barbault F , Paquet F , Huynh-Dinh T , Paoletti J ...
European Biophysics journal 31 (7), 521, 2002
232002
GPR40-mediated Gα12 activation by allosteric full agonists highly efficacious at potentiating glucose-stimulated insulin secretion in human islets
ML Rives, B Rady, N Swanson, S Zhao, J Qi, E Arnoult, I Bakaj, A Mancini, ...
Molecular Pharmacology 93 (6), 581-591, 2018
222018
Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B
DC McGowan, F Herschke, F Pauwels, B Stoops, I Smyej, S Last, ...
Journal of Medicinal Chemistry 60 (14), 6137-6151, 2017
152017
Discovery of novel benzo [b] thiophene tetrazoles as non-carboxylate GPR40 agonists
H Huang, MP Winters, SK Meegalla, E Arnoult, SP Lee, S Zhao, T Martin, ...
Bioorganic & Medicinal Chemistry Letters 28 (3), 429-436, 2018
142018
Discovery of selective 2, 4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists
S Pieters, D McGowan, F Herschke, F Pauwels, B Stoops, S Last, ...
Bioorganic & Medicinal Chemistry Letters 28 (4), 711-719, 2018
132018
Discovery of a novel potent GPR40 full agonist
SK Meegalla, H Huang, T Martin, J Xu, S Zhao, J Liu, M Hall, J Gunnet, ...
Bioorganic & Medicinal Chemistry Letters 28 (4), 720-726, 2018
102018
Potent long-acting inhibitors targeting the HIV-1 capsid based on a versatile quinazolin-4-one scaffold
EP Gillis, K Parcella, M Bowsher, JH Cook, C Iwuagwu, BN Naidu, ...
Journal of Medicinal Chemistry 66 (3), 1941-1954, 2023
82023
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