Arthur L. Shaffer
Arthur L. Shaffer
NIH NCI CCR Lymphoid Malignancies Branch üzerinde doğrulanmış e-posta adresine sahip - Ana Sayfa
Alıntı yapanlar
Alıntı yapanlar
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma
RE Davis, VN Ngo, G Lenz, P Tolar, RM Young, PB Romesser, ...
Nature 463 (7277), 88-92, 2010
Oncogenically active MYD88 mutations in human lymphoma
VN Ngo, RM Young, R Schmitz, S Jhavar, W Xiao, KH Lim, ...
Nature 470 (7332), 115-119, 2011
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
AL Shaffer, KI Lin, TC Kuo, X Yu, EM Hurt, A Rosenwald, JM Giltnane, ...
Immunity 17 (1), 51-62, 2002
Control of inflammation, cytokine expression, and germinal center formation by BCL-6
AL Dent, AL Shaffer, X Yu, D Allman, LM Staudt
Science 276 (5312), 589-592, 1997
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
AL Shaffer, X Yu, Y He, J Boldrick, EP Chan, LM Staudt
Immunity 13 (2), 199-212, 2000
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, SB Qian, H Zhao, ...
Immunity 21 (1), 81-93, 2004
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
G Lenz, GW Wright, NCT Emre, H Kohlhammer, SS Dave, RE Davis, ...
Proceedings of the National Academy of Sciences 105 (36), 13520-13525, 2008
Targeting B cell receptor signaling with ibrutinib in diffuse large B cell lymphoma
Nature Medicine, 2015
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
R Schmitz, RM Young, M Ceribelli, S Jhavar, W Xiao, M Zhang, G Wright, ...
Nature 490 (7418), 116-120, 2012
Genetics and pathogenesis of diffuse large B-cell lymphoma
R Schmitz, GW Wright, DW Huang, CA Johnson, JD Phelan, JQ Wang, ...
New England Journal of Medicine 378 (15), 1396-1407, 2018
IRF4 addiction in multiple myeloma
AL Shaffer, NCT Emre, L Lamy, VN Ngo, G Wright, W Xiao, J Powell, ...
Nature 454 (7201), 226-231, 2008
Lymphoid malignancies: the dark side of B-cell differentiation
AL Shaffer, A Rosenwald, LM Staudt
Nature Reviews Immunology 2 (12), 920-933, 2002
Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation
R Sciammas, AL Shaffer, JH Schatz, H Zhao, LM Staudt, H Singh
Immunity 25 (2), 225-236, 2006
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma
Y Yang, AL Shaffer III, NCT Emre, M Ceribelli, M Zhang, G Wright, W Xiao, ...
Cancer cell 21 (6), 723-737, 2012
Pathogenesis of human B cell lymphomas
AL Shaffer III, RM Young, LM Staudt
Annual review of immunology 30, 565-610, 2012
Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation
C Tunyaplin, AL Shaffer, CD Angelin-Duclos, X Yu, LM Staudt, KL Calame
The Journal of Immunology 173 (2), 1158-1165, 2004
Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma
EM Hurt, A Wiestner, A Rosenwald, AL Shaffer, E Campo, T Grogan, ...
Cancer cell 5 (2), 191-199, 2004
Signatures of the immune response
AL Shaffer, A Rosenwald, EM Hurt, JM Giltnane, LT Lam, OK Pickeral, ...
Immunity 15 (3), 375-385, 2001
Cell type–specific chromatin structure determines the targeting of V (D) J recombinase activity in vitro
P Stanhope-Baker, KM Hudson, AL Shaffer, A Constantinescu, ...
Cell 85 (6), 887-897, 1996
Cooperative epigenetic modulation by cancer amplicon genes
L Rui, NCT Emre, MJ Kruhlak, HJ Chung, C Steidl, G Slack, GW Wright, ...
Cancer cell 18 (6), 590-605, 2010
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Makaleler 1–20