Jeffrey M. Chen
Jeffrey M. Chen
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Roles of Lsr2 in Colony Morphology and Biofilm Formation of Mycobacterium smegmatis
JM Chen, GJ German, DC Alexander, H Ren, T Tan, J Liu
Journal of bacteriology 188 (2), 633-641, 2006
Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein
B Blasco, JM Chen, R Hartkoorn, C Sala, S Uplekar, J Rougemont, ...
PLoS pathogens 8 (3), e1002621, 2012
Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein
JM Chen, H Ren, JE Shaw, YJ Wang, M Li, AS Leung, V Tran, ...
Nucleic acids research 36 (7), 2123-2135, 2008
Identification of the lipooligosaccharide biosynthetic gene cluster from Mycobacterium marinum
H Ren, LG Dover, ST Islam, DC Alexander, JM Chen, GS Besra, J Liu
Molecular microbiology 63 (5), 1345-1359, 2007
Anticytolytic screen identifies inhibitors of mycobacterial virulence protein secretion
J Rybniker, JM Chen, C Sala, RC Hartkoorn, A Vocat, A Benjak, ...
Cell Host & Microbe 16 (4), 538-548, 2014
EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis
JM Chen, S Boy-Röttger, N Dhar, N Sweeney, RS Buxton, F Pojer, ...
Journal of bacteriology 194 (4), 884-893, 2012
ESAT-6 Secretion-Independent Impact of ESX-1 Genes espF and espG1 on Virulence of Mycobacterium tuberculosis
D Bottai, L Majlessi, R Simeone, W Frigui, C Laurent, P Lenormand, ...
Journal of Infectious Diseases 203 (8), 1155-1164, 2011
Differential productions of lipid virulence factors among BCG vaccine strains and implications on BCG safety
JM Chen, ST Islam, H Ren, J Liu
Vaccine 25 (48), 8114-8122, 2007
Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA‐independent virulence
JM Chen, M Zhang, J Rybniker, S Boy‐Röttger, N Dhar, F Pojer, ST Cole
Molecular microbiology 89 (6), 1154-1166, 2013
A Point Mutation in cycA Partially Contributes to the D-cycloserine Resistance Trait of Mycobacterium bovis BCG Vaccine Strains
JM Chen, S Uplekar, SV Gordon, ST Cole
Public Library of Science 7 (8), e43467, 2012
PimF, a mannosyltransferase of mycobacteria, is involved in the biosynthesis of phosphatidylinositol mannosides and lipoarabinomannan
DC Alexander, JRW Jones, T Tan, JM Chen, J Liu
Journal of Biological Chemistry 279 (18), 18824-18833, 2004
Mycobacterium bovis BCG Vaccines Exhibit Defects in Alanine and Serine Catabolism
JM Chen, DC Alexander, MA Behr, J Liu
Infection and immunity 71 (2), 708-716, 2003
Site-directed mutagenesis of acyl carrier protein (ACP) reveals amino acid residues involved in ACP structure and acyl-ACP synthetase activity
AS Flaman, JM Chen, SC Van Iderstine, DM Byers
Journal of Biological Chemistry 276 (38), 35934-35939, 2001
Phenotypic Profiling of Mycobacterium tuberculosis EspA Point Mutants Reveals that Blockage of ESAT-6 and CFP-10 Secretion In Vitro Does Not Always Correlate …
JM Chen, M Zhang, J Rybniker, L Basterra, N Dhar, AD Tischler, F Pojer, ...
Journal of bacteriology 195 (24), 5421-5430, 2013
The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron-sulfur cluster biogenesis and oxidative stress defence
J Rybniker, F Pojer, J Marienhagen, GS Kolly, JM Chen, E van Gumpel, ...
Biochemical journal 459 (3), 467-478, 2014
EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis
M Zhang, JM Chen, C Sala, J Rybniker, N Dhar, ST Cole
Molecular microbiology 93 (5), 1057-1065, 2014
Towards anti-virulence drugs targeting ESX-1 mediated pathogenesis of Mycobacterium tuberculosis
JM Chen, F Pojer, B Blasco, ST Cole
Drug Discovery Today: Disease Mechanisms 7 (1), e25-e31, 2010
Sigma Factor F Does Not Prevent Rifampin Inhibition of RNA Polymerase or Cause Rifampin Tolerance in Mycobacterium tuberculosis
RC Hartkoorn, C Sala, SJ Magnet, JM Chen, F Pojer, ST Cole
Journal of bacteriology 192 (20), 5472-5479, 2010
Mycosins of the mycobacterial type VII ESX secretion system: the glue that holds the party together
JM Chen
Mbio 7 (6), 10.1128/mbio. 02062-16, 2016
Poor stimulation of bovine dendritic cells by Mycobacterium bovis culture supernatant and surface extract is associated with decreased activation of ERK and NF-κ B and higher …
O Ihedioha, AA Potter, JM Chen
Innate Immunity 26 (6), 537-546, 2020
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