The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer M O'hayre, J Vázquez-Prado, I Kufareva, EW Stawiski, TM Handel, ... Nature reviews cancer 13 (6), 412-424, 2013 | 567 | 2013 |
Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment M O'Hayre, CL Salanga, TM Handel, SJ Allen Biochemical Journal 409 (3), 635-649, 2008 | 368 | 2008 |
Novel insights into G protein and G protein-coupled receptor signaling in cancer M O’Hayre, MS Degese, JS Gutkind Current opinion in cell biology 27, 126-135, 2014 | 303 | 2014 |
Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK M O’Hayre, K Eichel, S Avino, X Zhao, DJ Steffen, X Feng, K Kawakami, ... Science signaling 10 (484), eaal3395, 2017 | 210 | 2017 |
Modulation of chemokine receptor activity through dimerization and crosstalk CL Salanga, M O’Hayre, T Handel Cellular and molecular life sciences 66, 1370-1386, 2009 | 109 | 2009 |
Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysis M O'Hayre, CL Salanga, TJ Kipps, D Messmer, PC Dorrestein, TM Handel PloS one 5 (7), e11716, 2010 | 100 | 2010 |
Inactivating mutations in GNA13 and RHOA in Burkitt’s lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells M O'Hayre, A Inoue, I Kufareva, Z Wang, CM Mikelis, RA Drummond, ... Oncogene 35 (29), 3771-3780, 2016 | 85 | 2016 |
Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3) S Qi, M O'Hayre, JS Gutkind, JH Hurley Journal of Biological Chemistry 289 (8), 4743-4752, 2014 | 78 | 2014 |
Chronic lymphocytic leukemia cells receive RAF-dependent survival signals in response to CXCL12 that are sensitive to inhibition by sorafenib D Messmer, JF Fecteau, M O'Hayre, IS Bharati, TM Handel, TJ Kipps Blood, The Journal of the American Society of Hematology 117 (3), 882-889, 2011 | 73 | 2011 |
Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1) JF Fecteau, IS Bharati, M O’Hayre, TM Handel, TJ Kipps, D Messmer Molecular Medicine 18, 19-28, 2012 | 51 | 2012 |
Emerging concepts and approaches for chemokine-receptor drug discovery M O'Hayre, CL Salanga, TM Handel, DJ Hamel Expert opinion on drug discovery 5 (11), 1109-1122, 2010 | 39 | 2010 |
Oral health disparities: a perspective from the National Institute of Dental and Craniofacial Research DJ Fischer, M O’Hayre, JW Kusiak, MJ Somerman, CV Hill American journal of public health 107 (S1), S36-S38, 2017 | 36 | 2017 |
Autotherapies: enhancing endogenous healing and regeneration N Lumelsky, M O’Hayre, P Chander, L Shum, MJ Somerman Trends in Molecular Medicine 24 (11), 919-930, 2018 | 25 | 2018 |
The homozygous CX3CR1-M280 mutation impairs human monocyte survival AL Collar, M Swamydas, M O’Hayre, MS Sajib, KW Hoffman, SP Singh, ... JCI insight 3 (3), 2018 | 24 | 2018 |
Insights into β2‐adrenergic receptor binding from structures of the N‐terminal lobe of ARRDC 3 S Qi, M O'Hayre, JS Gutkind, JH Hurley Protein Science 23 (12), 1708-1716, 2014 | 22 | 2014 |
Mechanisms and consequences of the loss of PHLPP1 phosphatase in chronic lymphocytic leukemia (CLL) M O'hayre, M Niederst, JF Fecteau, VM Nguyen, TJ Kipps, D Messmer, ... Leukemia 26 (7), 1689-1692, 2012 | 19 | 2012 |
TGF-β signaling and its effect on glutaminase expression in LLC-PK1-FBPase+ cells M Andratsch, E Feifel, L Taylor, M O'Hayre, H Schramek, NP Curthoys, ... American Journal of Physiology-Renal Physiology 293 (3), F846-F853, 2007 | 16 | 2007 |
Phosphoproteomic analysis of chemokine signaling networks M O'Hayre, CL Salanga, PC Dorrestein, TM Handel Methods in enzymology 460, 331-346, 2009 | 14 | 2009 |
Effects of constitutively active and dominant negative MAPK kinase (MKK) 3 and MKK6 on the pH-responsive increase in phosphoenolpyruvate carboxykinase mRNA M O'Hayre, L Taylor, M Andratsch, E Feifel, G Gstraunthaler, NP Curthoys Journal of Biological Chemistry 281 (5), 2982-2988, 2006 | 12 | 2006 |
The NIH’s Funding to US Dental Institutions from 2005 to 2014 DJ Ferland, CL, O'Hayre, M, Knosp, K, Fox CH, Horsford Journal of Dental Research 96 (1), 10-16, 2017 | 10 | 2017 |