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Tobias Bittner
Tobias Bittner
F.Hoffmann-LaRoche/Genentech
Verified email at roche.com
Title
Cited by
Cited by
Year
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
M Fuhrmann, T Bittner, CKE Jung, S Burgold, RM Page, G Mitteregger, ...
Nature neuroscience 13 (4), 411-413, 2010
6242010
CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: a study of fully automated immunoassays in BioFINDER and ADNI cohorts
O Hansson, J Seibyl, E Stomrud, H Zetterberg, JQ Trojanowski, T Bittner, ...
Alzheimer's & dementia 14 (11), 1470-1481, 2018
5462018
Current state of Alzheimer’s fluid biomarkers
JL Molinuevo, S Ayton, R Batrla, MM Bednar, T Bittner, J Cummings, ...
Acta neuropathologica 136, 821-853, 2018
4912018
Performance of fully automated plasma assays as screening tests for Alzheimer disease–related β-amyloid status
S Palmqvist, S Janelidze, E Stomrud, H Zetterberg, J Karl, K Zink, T Bittner, ...
JAMA neurology 76 (9), 1060-1069, 2019
3592019
Technical performance of a novel, fully automated electrochemiluminescence immunoassay for the quantitation of β-amyloid (1–42) in human cerebrospinal fluid
T Bittner, H Zetterberg, CE Teunissen, RE Ostlund Jr, M Militello, ...
Alzheimer's & dementia 12 (5), 517-526, 2016
3012016
Head-to-head comparison of 8 plasma amyloid-β 42/40 assays in Alzheimer disease
S Janelidze, CE Teunissen, H Zetterberg, JA Allué, L Sarasa, ...
JAMA neurology 78 (11), 1375-1382, 2021
2212021
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice
T Bittner, M Fuhrmann, S Burgold, SM Ochs, N Hoffmann, G Mitteregger, ...
PloS one 5 (11), e15477, 2010
1692010
Mass spectrometry–based candidate reference measurement procedure for quantification of amyloid-β in cerebrospinal fluid
A Leinenbach, J Pannee, T Dülffer, A Huber, T Bittner, U Andreasson, ...
Clinical chemistry 60 (7), 987-994, 2014
1502014
Rescue of progranulin deficiency associated with frontotemporal lobar degeneration by alkalizing reagents and inhibition of vacuolar ATPase
A Capell, S Liebscher, K Fellerer, N Brouwers, M Willem, S Lammich, ...
Journal of Neuroscience 31 (5), 1885-1894, 2011
1502011
γ-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway
T Bittner, M Fuhrmann, S Burgold, CKE Jung, C Volbracht, H Steiner, ...
Journal of Neuroscience 29 (33), 10405-10409, 2009
1382009
Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: an update from the Alzheimer's Association Global Biomarkers Consortium
MC Carrillo, K Blennow, H Soares, P Lewczuk, N Mattsson, P Oberoi, ...
Alzheimer's & Dementia 9 (2), 137-140, 2013
1372013
CSF Aβ1–42–an excellent but complicated Alzheimer's biomarker–a route to standardisation
J Kuhlmann, U Andreasson, J Pannee, M Bjerke, E Portelius, ...
Clinica Chimica Acta 467, 27-33, 2017
1272017
Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in …
S Salloway, LA Honigberg, W Cho, M Ward, M Friesenhahn, F Brunstein, ...
Alzheimer's research & therapy 10, 1-13, 2018
1252018
Amyloid plaque formation precedes dendritic spine loss
T Bittner, S Burgold, MM Dorostkar, M Fuhrmann, BM Wegenast-Braun, ...
Acta neuropathologica 124, 797-807, 2012
1212012
Practical recommendations for timely, accurate diagnosis of symptomatic Alzheimer’s disease (MCI and dementia) in primary care: a review and synthesis
JL Liss, S Seleri Assunção, J Cummings, A Atri, DS Geldmacher, ...
Journal of internal medicine 290 (2), 310-334, 2021
1112021
In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks
S Burgold, T Bittner, MM Dorostkar, D Kieser, M Fuhrmann, G Mitteregger, ...
Acta neuropathologica 121, 327-335, 2011
1002011
Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons
M Fuhrmann, T Bittner, G Mitteregger, N Haider, S Moosmang, ...
Journal of neurochemistry 98 (6), 1876-1885, 2006
972006
Bis (arylvinyl) pyrazines,-pyrimidines, and-pyridazines as imaging agents for tau fibrils and β-amyloid plaques in Alzheimer’s disease models
A Boländer, D Kieser, C Voss, S Bauer, C Schön, S Burgold, T Bittner, ...
Journal of Medicinal Chemistry 55 (21), 9170-9180, 2012
892012
Preanalytical sample handling recommendations for Alzheimer's disease plasma biomarkers
M Rózga, T Bittner, R Batrla, J Karl
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 11, 291-300, 2019
822019
Target engagement in an alzheimer trial: Crenezumab lowers amyloid β oligomers in cerebrospinal fluid
T Yang, Y Dang, B Ostaszewski, D Mengel, V Steffen, C Rabe, T Bittner, ...
Annals of neurology 86 (2), 215-224, 2019
812019
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