| Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum NMB Brancucci, JP Gerdt, CQ Wang, M De Niz, N Philip, SR Adapa, ... Cell 171 (7), 1532-1544. e15, 2017 | 299 | 2017 |
| Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases R Chowdhury, JI Candela-Lena, MC Chan, DJ Greenald, KK Yeoh, ... ACS chemical biology 8 (7), 1488-1496, 2013 | 138 | 2013 |
| Homochiral drugs: a demanding tendency of the pharmaceutical industry MC Nunez, ME Garcia-Rubino, A Conejo-Garcia, O Cruz-Lopez, ... Current medicinal chemistry 16 (16), 2064-2074, 2009 | 121 | 2009 |
| Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line R Sánchez-Martín, JM Campos, A Conejo-García, O Cruz-López, ... Journal of medicinal chemistry 48 (9), 3354-3363, 2005 | 78 | 2005 |
| Novel substituted quinazolines for potent EGFR tyrosine kinase inhibitors O Cruz-Lopez, A Conejo-Garcia, M C Nunez, M Kimatrai, ... Current medicinal chemistry 18 (7), 943-963, 2011 | 70 | 2011 |
| New (RS)-benzoxazepin-purines with antitumour activity: the chiral switch from (RS)-2, 6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1, 2, 3, 5-tetrahydro-4, 1-benzoxazepin-3-yl]-9H … LC López-Cara, A Conejo-García, JA Marchal, G Macchione, ... European Journal of Medicinal Chemistry 46 (1), 249-258, 2011 | 50 | 2011 |
| QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be? J Campos, MC Núñez, A Conejo-García, RM Sánchez-Martín, ... Current medicinal chemistry 10 (13), 1095-1112, 2003 | 50 | 2003 |
| Synthesis and anticancer activity of (RS)-9-(2, 3-dihydro-1, 4-benzoxaheteroin-2-ylmethyl)-9H-purines A Conejo-García, ME García-Rubiño, JA Marchal, MC Núñez, A Ramirez, ... European journal of medicinal chemistry 46 (9), 3795-3801, 2011 | 49 | 2011 |
| The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor M Sahún‐Roncero, B Rubio‐Ruiz, G Saladino, A Conejo‐García, ... Angewandte Chemie International Edition 52 (17), 4582-4586, 2013 | 47 | 2013 |
| Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl-and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic … A Conejo-García, L Pisani, M del Carmen Núñez, M Catto, O Nicolotti, ... Journal of medicinal chemistry 54 (8), 2627-2645, 2011 | 45 | 2011 |
| Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors A Conejo-García, JM Campos, RM Sánchez-Martín, MÁ Gallo, A Espinosa Journal of medicinal chemistry 46 (17), 3754-3757, 2003 | 44 | 2003 |
| Synthesis and Anticancer Activity of (R,S)‐9‐(2,3‐Dihydro‐1,4‐Benzoxathiin‐3‐ylmethyl)‐9H‐Purines M Díaz‐Gavilán, A Conejo‐García, O Cruz‐López, MC Nunez, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (1), 127-135, 2008 | 42 | 2008 |
| Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death L Serrán-Aguilera, H Denton, B Rubio-Ruiz, B López-Gutiérrez, A Entrena, ... Scientific reports 6 (1), 33189, 2016 | 38 | 2016 |
| Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7-or 9-(2, 3-dihydro-5H-1, 4-benzodioxepin-3-yl)-7H-or … A Conejo-Garcia, MC Nunez, JA Marchal, F Rodriguez-Serrano, ... European journal of medicinal chemistry 43 (8), 1742-1748, 2008 | 38 | 2008 |
| The inhibition of factor inhibiting hypoxia-inducible factor (FIH) by β-oxocarboxylic acids B Banerji, A Conejo-Garcia, LA McNeill, MA McDonough, MRG Buck, ... Chemical communications, 5438-5440, 2005 | 36 | 2005 |
| Influence of the linker in bispyridium compounds on the inhibition of human choline kinase A Conejo-García, M Báñez-Coronel, RM Sánchez-Martín, ... Journal of medicinal chemistry 47 (22), 5433-5440, 2004 | 36 | 2004 |
| Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors B Rubio-Ruíz, A Conejo-García, P Ríos-Marco, MP Carrasco-Jiménez, ... European journal of medicinal chemistry 50, 154-162, 2012 | 33 | 2012 |
| HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib A Ramírez, H Boulaiz, C Morata-Tarifa, M Perán, G Jiménez, ... Oncotarget 5 (11), 3590, 2014 | 31 | 2014 |
| Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1, 4-dihetero seven-and six-membered tethered pyrimidines and purines MC Nunez, M Diaz-Gavilan, A Conejo-Garcia, O Cruz-Lopez, MA Gallo, ... Current medicinal chemistry 15 (25), 2614-2631, 2008 | 31 | 2008 |
| Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence JA Marchal, E Carrasco, A Ramirez, G Jiménez, C Olmedo, M Peran, ... Drug Design, Development and Therapy, 1301-1313, 2013 | 30 | 2013 |
