| Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture AH De Wilde, D Jochmans, CC Posthuma, JC Zevenhoven-Dobbe, ... Antimicrobial agents and chemotherapy 58 (8), 4875-4884, 2014 | 898 | 2014 |
| TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates S De Meyer, H Azijn, D Surleraux, D Jochmans, A Tahri, R Pauwels, ... Antimicrobial agents and chemotherapy 49 (6), 2314-2321, 2005 | 466 | 2005 |
| Remdesivir, Molnupiravir and Nirmatrelvir remain active against SARS-CoV-2 Omicron and other variants of concern L Vangeel, W Chiu, S De Jonghe, P Maes, B Slechten, J Raymenants, ... Antiviral research 198, 105252, 2022 | 395 | 2022 |
| TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1 H Azijn, I Tirry, J Vingerhoets, MP de Béthune, G Kraus, K Boven, ... Antimicrobial agents and chemotherapy 54 (2), 718-727, 2010 | 350 | 2010 |
| TMC125 displays a high genetic barrier to the development of resistance: evidence from in vitro selection experiments J Vingerhoets, H Azijn, E Fransen, I De Baere, L Smeulders, D Jochmans, ... Journal of virology 79 (20), 12773-12782, 2005 | 340 | 2005 |
| STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters R Boudewijns, HJ Thibaut, SJF Kaptein, R Li, V Vergote, L Seldeslachts, ... Nature communications 11 (1), 5838, 2020 | 273 | 2020 |
| Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral L Delang, N Segura Guerrero, A Tas, G Quérat, B Pastorino, M Froeyen, ... Journal of Antimicrobial Chemotherapy 69 (10), 2770-2784, 2014 | 249 | 2014 |
| SARS-CoV-2 Mpro inhibitors and activity-based probes for patient-sample imaging W Rut, K Groborz, L Zhang, X Sun, M Zmudzinski, B Pawlik, X Wang, ... Nature chemical biology 17 (2), 222-228, 2021 | 232 | 2021 |
| Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors O Goethals, R Clayton, M Van Ginderen, I Vereycken, E Wagemans, ... Journal of virology 82 (21), 10366-10374, 2008 | 189 | 2008 |
| SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell Stem Cell 29 (2), 217-231. e8, 2022 | 171 | 2022 |
| Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2 J Baggen, L Persoons, E Vanstreels, S Jansen, D Van Looveren, ... Nature Genetics 53 (4), 435-444, 2021 | 170 | 2021 |
| Novel HIV-1 reverse transcriptase inhibitors D Jochmans Virus research 134 (1-2), 171-185, 2008 | 156 | 2008 |
| Inherited IFNAR1 deficiency in otherwise healthy patients with adverse reaction to measles and yellow fever live vaccines N Hernandez, G Bucciol, L Moens, J Le Pen, M Shahrooei, E Goudouris, ... Journal of Experimental Medicine 216 (9), 2057-2070, 2019 | 153 | 2019 |
| Ultralarge virtual screening identifies SARS-CoV-2 main protease inhibitors with broad-spectrum activity against coronaviruses A Luttens, H Gullberg, E Abdurakhmanov, DD Vo, D Akaberi, VO Talibov, ... Journal of the American Chemical Society 144 (7), 2905-2920, 2022 | 150 | 2022 |
| Favipiravir (T-705) inhibits in vitro norovirus replication J Rocha-Pereira, D Jochmans, K Dallmeier, P Leyssen, MSJ Nascimento, ... Biochemical and biophysical research communications 424 (4), 777-780, 2012 | 146 | 2012 |
| Inhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agent RG Ptak, PA Gallay, D Jochmans, AP Halestrap, UT Ruegg, LA Pallansch, ... Antimicrobial agents and chemotherapy 52 (4), 1302-1317, 2008 | 145 | 2008 |
| The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model R Abdelnabi, CS Foo, SJF Kaptein, X Zhang, TND Do, L Langendries, ... EBioMedicine 72, 2021 | 117 | 2021 |
| The Viral Polymerase Inhibitor 2′-C-Methylcytidine Inhibits Norwalk Virus Replication and Protects against Norovirus-Induced Diarrhea and Mortality in a Mouse … J Rocha-Pereira, D Jochmans, Y Debing, E Verbeken, MSJ Nascimento, ... Journal of virology 87 (21), 11798-11805, 2013 | 111 | 2013 |
| Identification of inhibitors of SARS-CoV-2 3CL-pro enzymatic activity using a small molecule in vitro repurposing screen M Kuzikov, E Costanzi, J Reinshagen, F Esposito, L Vangeel, M Wolf, ... ACS pharmacology & translational science 4 (3), 1096-1110, 2021 | 110 | 2021 |
| Indolopyridones inhibit human immunodeficiency virus reverse transcriptase with a novel mechanism of action D Jochmans, J Deval, B Kesteleyn, H Van Marck, E Bettens, I De Baere, ... Journal of virology 80 (24), 12283-12292, 2006 | 110 | 2006 |
Joana Rocha-PereiraAssistant Professorkuleuven.be üzerinde doğrulanmış e-posta adresine sahip
