| Expanded encyclopaedias of DNA elements in the human and mouse genomes JE Moore, MJ Purcaro, HE Pratt, CB Epstein, N Shoresh, J Adrian, T Kawli, ... Nature 583 (7818), 699-710, 2020 | 1167 | 2020 |
| Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain BB Lake*, R Ai*, GE Kaeser*, NS Salathia*, YC Yung, R Liu, A Wildberg, ... Science 352 (6293), 1586-1590, 2016 | 907 | 2016 |
| Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes R Ai, T Laragione, D Hammaker, DL Boyle, A Wildberg, K Maeshima, ... Nature communications 9 (1), 1921, 2018 | 159 | 2018 |
| Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes R Ai, D Hammaker, DL Boyle, R Morgan, AM Walsh, S Fan, GS Firestein, ... Nature communications 7 (1), 11849, 2016 | 135 | 2016 |
| Normalization and noise reduction for single cell RNA-seq experiments B Ding, L Zheng, Y Zhu, N Li, H Jia, R Ai, A Wildberg, W Wang Bioinformatics 31 (13), 2225-2227, 2015 | 116 | 2015 |
| Perspectives on ENCODE MP Snyder, TR Gingeras, JE Moore, Z Weng, MB Gerstein, B Ren, ... Nature 583 (7818), 693-698, 2020 | 92 | 2020 |
| DNA methylome signature in early rheumatoid arthritis synoviocytes compared with longstanding rheumatoid arthritis synoviocytes R Ai, JW Whitaker, DL Boyle, PP Tak, DM Gerlag, W Wang, GS Firestein Arthritis & rheumatology (Hoboken, NJ) 67 (7), 1978, 2015 | 87* | 2015 |
| Abnormal PTPN11 enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation K Maeshima, SM Stanford, D Hammaker, C Sacchetti, L Zeng, R Ai, ... JCI insight 1 (7), 2016 | 53 | 2016 |
| Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal MND Svensson, M Zoccheddu, S Yang, G Nygaard, C Secchi, KM Doody, ... Science Advances 6 (26), eaba4353, 2020 | 48 | 2020 |
| Predicting CpG methylation levels by integrating Infinium HumanMethylation450 BeadChip array data S Fan, K Huang, R Ai, M Wang, W Wang Genomics 107 (4), 132-137, 2016 | 41 | 2016 |
| Assessing characteristics of RNA amplification methods for single cell RNA sequencing BMC Genomics, 966, 2016 | 40* | 2016 |
| Enhancing KDM5A and TLR activity improves the response to immune checkpoint blockade L Wang, Y Gao, G Zhang, D Li, Z Wang, J Zhang, LC Hermida, L He, ... Science Translational Medicine 12 (560), eaax2282, 2020 | 39 | 2020 |
| Integrative analysis with expanded DNA methylation data reveals common key regulators and pathways in cancers S Fan, J Tang, N Li, Y Zhao, R Ai, K Zhang, M Wang, W Du, W Wang NPJ genomic medicine 4 (1), 2, 2019 | 36 | 2019 |
| Identification of DNA motifs that regulate DNA methylation M Wang, K Zhang, V Ngo, C Liu, S Fan, JW Whitaker, Y Chen, R Ai, ... Nucleic Acids Research 47 (13), 6753-6768, 2019 | 35 | 2019 |
| PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes A Bottini, DJ Wu, R Ai, M Le Roux, B Bartok, M Bombardieri, KM Doody, ... Annals of the rheumatic diseases 78 (5), 600-609, 2019 | 35 | 2019 |
| T-Analyst: a program for efficient analysis of protein conformational changes by torsion angles R Ai, M Qaiser Fatmi, CA Chang Journal of computer-aided molecular design 24, 819-827, 2010 | 35 | 2010 |
| Computationally expanding infinium HumanMethylation450 BeadChip array data to reveal distinct DNA methylation patterns of rheumatoid arthritis S Fan, C Li, R Ai, M Wang, GS Firestein, W Wang Bioinformatics 32 (12), 1773-1778, 2016 | 30 | 2016 |
| Synergistic regulation and ligand-induced conformational changes of tryptophan synthase MQ Fatmi, R Ai, CA Chang Biochemistry 48 (41), 9921-9931, 2009 | 30 | 2009 |
| Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis D Beckmann, A Römer-Hillmann, A Krause, U Hansen, C Wehmeyer, ... Nature Communications 12 (1), 3624, 2021 | 22 | 2021 |
| Joint location–specific JAK‐STAT signaling in rheumatoid arthritis fibroblast‐like synoviocytes D Hammaker, G Nygaard, A Kuhs, R Ai, DL Boyle, W Wang, GS Firestein ACR open rheumatology 1 (10), 640-648, 2019 | 22 | 2019 |
David L. BoyleUniversity of California, San Diego Verified email at ucsd.edu
