| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13127* | 2021 |
| Resveratrol improves health and survival of mice on a high-calorie diet JA Baur, KJ Pearson, NL Price, HA Jamieson, C Lerin, A Kalra, ... Nature 444 (7117), 337-342, 2006 | 5337 | 2006 |
| AMPK phosphorylation of raptor mediates a metabolic checkpoint DM Gwinn, DB Shackelford, DF Egan, MM Mihaylova, A Mery, ... Molecular cell 30 (2), 214-226, 2008 | 4310 | 2008 |
| The AMPK signalling pathway coordinates cell growth, autophagy and metabolism MM Mihaylova, RJ Shaw Nature cell biology 13 (9), 1016-1023, 2011 | 3005 | 2011 |
| AMPK: guardian of metabolism and mitochondrial homeostasis S Herzig, RJ Shaw Nature reviews Molecular cell biology 19 (2), 121-135, 2018 | 2721 | 2018 |
| Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy DF Egan, DB Shackelford, MM Mihaylova, S Gelino, RA Kohnz, W Mair, ... Science 331 (6016), 456-461, 2011 | 2665 | 2011 |
| Ras, PI (3) K and mTOR signalling controls tumour cell growth RJ Shaw, LC Cantley Nature 441 (7092), 424-430, 2006 | 2610 | 2006 |
| The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ... Science 310 (5754), 1642-1646, 2005 | 2345 | 2005 |
| The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress RJ Shaw, M Kosmatka, N Bardeesy, RL Hurley, LA Witters, RA DePinho, ... Proceedings of the National Academy of Sciences 101 (10), 3329-3335, 2004 | 2127 | 2004 |
| The LKB1–AMPK pathway: metabolism and growth control in tumour suppression DB Shackelford, RJ Shaw Nature Reviews Cancer 9 (8), 563-575, 2009 | 2068 | 2009 |
| AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice YU Li, S Xu, MM Mihaylova, B Zheng, X Hou, B Jiang, O Park, Z Luo, ... Cell metabolism 13 (4), 376-388, 2011 | 1729 | 2011 |
| AMPK: mechanisms of cellular energy sensing and restoration of metabolic balance D Garcia, RJ Shaw Molecular cell 66 (6), 789-800, 2017 | 1515 | 2017 |
| AMPK and PPARδ agonists are exercise mimetics VA Narkar, M Downes, TY Ruth, E Embler, YX Wang, E Banayo, ... Cell 134 (3), 405-415, 2008 | 1471 | 2008 |
| The LKB1 tumor suppressor negatively regulates mTOR signaling RJ Shaw, N Bardeesy, BD Manning, L Lopez, M Kosmatka, RA DePinho, ... Cancer cell 6 (1), 91-99, 2004 | 1248 | 2004 |
| AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation KA Lamia, UM Sachdeva, L DiTacchio, EC Williams, JG Alvarez, DF Egan, ... Science 326 (5951), 437-440, 2009 | 1016 | 2009 |
| AMP-activated protein kinase mediates mitochondrial fission in response to energy stress EQ Toyama, S Herzig, J Courchet, TL Lewis Jr, OC Losón, K Hellberg, ... Science 351 (6270), 275-281, 2016 | 969 | 2016 |
| LKB1 and AMP‐activated protein kinase control of mTOR signalling and growth RJ Shaw Acta physiologica 196 (1), 65-80, 2009 | 758 | 2009 |
| Glucose metabolism and cancer RJ Shaw Current opinion in cell biology 18 (6), 598-608, 2006 | 702 | 2006 |
| Small molecule inhibition of the autophagy kinase ULK1 and identification of ULK1 substrates DF Egan, MGH Chun, M Vamos, H Zou, J Rong, CJ Miller, HJ Lou, ... Molecular cell 59 (2), 285-297, 2015 | 673 | 2015 |
| The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR D Egan, J Kim, RJ Shaw, KL Guan Autophagy 7 (6), 643-644, 2011 | 640 | 2011 |
