| Design, synthesis, and SAR of tachykinin antagonists: Modulation of balance in NK1/NK2 receptor antagonist activity JS Albert, D Aharony, D Andisik, H Barthlow, PR Bernstein, RA Bialecki, ... Journal of medicinal chemistry 45 (18), 3972-3983, 2002 | 82 | 2002 |
| Development and SAR of functionally selective allosteric modulators of GABAA receptors C Alhambra, C Becker, T Blake, JR Damewood Jr, T Daniels, ... Bioorganic & medicinal chemistry 19 (9), 2927-2938, 2011 | 54 | 2011 |
| A new route for manufacture of 3-cyano-1-naphthalenecarboxylic acid IW Ashworth, MC Bowden, B Dembofsky, D Levin, W Moss, E Robinson, ... Organic process research & development 7 (1), 74-81, 2003 | 53 | 2003 |
| Discovery of novel, orally active dual NK1/NK2 antagonists PR Bernstein, D Aharony, JS Albert, D Andisik, HG Barthlow, R Bialecki, ... Bioorganic & medicinal chemistry letters 11 (20), 2769-2773, 2001 | 50 | 2001 |
| Subsite requirements for peptide aldehyde inhibitors of human calpain I M Iqbal, PA Messina, B Freed, M Das, S Chatterjee, R Tripathy, M Tao, ... Bioorganic & Medicinal Chemistry Letters 7 (5), 539-544, 1997 | 50 | 1997 |
| 5 (R)-Methyl-1-(chloromethyl)-2-pyrrolidinone: a new reagent for the determination of enantiomeric composition of alcohols MB Smith, BT Dembofsky, YC Son The Journal of Organic Chemistry 59 (7), 1719-1725, 1994 | 43 | 1994 |
| Design and optimization of cyclized NK1 antagonists with controlled atropisomeric properties JS Albert, C Ohnmacht, PR Bernstein, WL Rumsey, D Aharony, BB Masek, ... Tetrahedron 60 (20), 4337-4347, 2004 | 38 | 2004 |
| Azepines and piperidines with dual norepinephrine dopamine uptake inhibition and antidepressant activity DG Brown, PR Bernstein, Y Wu, RA Urbanek, CW Becker, SR Throner, ... ACS Medicinal Chemistry Letters 4 (1), 46-51, 2013 | 26 | 2013 |
| Compounds and uses thereof MJ Chapdelaine, CJ Ohnmacht, C Becker, HF Chang, BT Dembofsky US Patent 7,425,556, 2008 | 26 | 2008 |
| Compounds and Uses Thereof-848 HF Chang, M Chapdelaine, BT Dembofsky, KJ Herzog, C Horchler, ... US Patent App. 12/141,190, 2008 | 25 | 2008 |
| Naphtho [2, 1-b][1, 5] and [1, 2-f][1, 4] oxazocines as selective NK1 antagonists CJ Ohnmacht, JS Albert, PR Bernstein, WL Rumsey, BB Masek, ... Bioorganic & medicinal chemistry 12 (10), 2653-2669, 2004 | 23 | 2004 |
| Compounds and Uses Thereof MJ Chapdelaine, CJ Ohnmacht, C Becker, HF Chang, BT Dembofsky US Patent App. 12/199,034, 2009 | 16 | 2009 |
| Late-occurring and long-circulating metabolites of GABAAα2, 3 receptor modulator AZD7325 involving metabolic cyclization and aromatization: Relevance to MIST analysis and … C Gu, M Artelsmair, CS Elmore, RJ Lewis, P Davis, JE Hall, ... Drug Metabolism and Disposition 46 (3), 303-315, 2018 | 13 | 2018 |
| Synthesis of Single-Enantiomer 6-Hydroxy-7-phenyl-1, 4-oxazepan-5-ones CW Becker, BT Dembofsky, JE Hall, RT Jacobs, DE Pivonka, ... Synthesis 2005 (15), 2549-2561, 2005 | 13 | 2005 |
| A New Lactam Protecting Group. MB Smith, CJ Wang, PF Keusenkothen, BT Dembofsky, JG Fay, CA Zezza, ... Chemistry Letters, 247-250, 1992 | 13 | 1992 |
| Compounds and Uses Thereof MJ Chapdelaine, CJ Ohnmacht, C Becker, HF Chang, BT Dembofsky US Patent App. 12/169,824, 2009 | 11 | 2009 |
| Therapeutic neurokinin receptor antagonist compounds PR Bernstein, BT Dembofsky US Patent 6,090,824, 2000 | 8 | 2000 |
| GENESIS AND DEGRADATION OF A-BETA PROTEIN BY CULTURED HUMAN NEUROBLASTOMA-CELLS R Siman, JT Durkin, JK KAWOOYA, EJ HUSTEN, S Murthy, T EMMONS, ... NEUROBIOLOGY OF AGING 15, S159-S159, 1994 | 7 | 1994 |
| Bicyclo ((aryl) methyl) benzamides as inhibitors of GlyT1 JG Varnes, H Xiong, JM Forst, CR Holmquist, GE Ernst, W Frietze, ... Bioorganic & Medicinal Chemistry Letters 28 (6), 1043-1049, 2018 | 3 | 2018 |
| Process for the preparation of 3-cyano-1-naphthoic acid and some analogues thereof I Ashworth, M Bowden, B Dembofsky, D Levin US Patent App. 10/518,300, 2005 | 3 | 2005 |
