Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5 M Vijay-Kumar, JD Aitken, FA Carvalho, TC Cullender, S Mwangi, ... Science 328 (5975), 228-231, 2010 | 2399 | 2010 |
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome B Chassaing, O Koren, JK Goodrich, AC Poole, S Srinivasan, RE Ley, ... Nature 519 (7541), 92-96, 2015 | 1955 | 2015 |
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression AT Gewirtz, TA Navas, S Lyons, PJ Godowski, JL Madara The Journal of Immunology 167 (4), 1882-1885, 2001 | 1749 | 2001 |
Prokaryotic regulation of epithelial responses by inhibition of IκB-α ubiquitination AS Neish, AT Gewirtz, H Zeng, AN Young, ME Hobert, V Karmali, AS Rao, ... Science 289 (5484), 1560-1563, 2000 | 1180 | 2000 |
Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis MEV Johansson, JK Gustafsson, J Holmén-Larsson, KS Jabbar, L Xia, ... Gut 63 (2), 281-291, 2014 | 925 | 2014 |
Cutting edge: impaired Toll-like receptor expression and function in aging M Renshaw, J Rockwell, C Engleman, A Gewirtz, J Katz, S Sambhara The Journal of Immunology 169 (9), 4697-4701, 2002 | 731 | 2002 |
Dysregulation of inflammatory responses by chronic circadian disruption O Castanon-Cervantes, M Wu, JC Ehlen, K Paul, KL Gamble, RL Johnson, ... The Journal of Immunology 185 (10), 5796-5805, 2010 | 586 | 2010 |
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf A Amer, L Franchi, TD Kanneganti, M Body-Malapel, N Ozoren, G Brady, ... Journal of Biological Chemistry 281 (46), 35217-35223, 2006 | 570 | 2006 |
Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics JY Li, B Chassaing, AM Tyagi, C Vaccaro, T Luo, J Adams, TM Darby, ... The Journal of clinical investigation 126 (6), 2049-2063, 2016 | 520 | 2016 |
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response AT Gewirtz, PO Simon, CK Schmitt, LJ Taylor, CH Hagedorn, AD O’Brien, ... The Journal of clinical investigation 107 (1), 99-109, 2001 | 519 | 2001 |
Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice FA Carvalho, O Koren, JK Goodrich, MEV Johansson, I Nalbantoglu, ... Cell host & microbe 12 (2), 139-152, 2012 | 512 | 2012 |
Deletion of TLR5 results in spontaneous colitis in mice M Vijay-Kumar, CJ Sanders, RT Taylor, A Kumar, JD Aitken, ... The Journal of clinical investigation 117 (12), 3909-3921, 2007 | 504 | 2007 |
TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination JZ Oh, R Ravindran, B Chassaing, FA Carvalho, MS Maddur, M Bower, ... Immunity 41 (3), 478-492, 2014 | 501 | 2014 |
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation B Chassaing, G Srinivasan, MA Delgado, AN Young, AT Gewirtz, ... Public Library of Science 7 (9), e44328, 2012 | 496 | 2012 |
Fiber-mediated nourishment of gut microbiota protects against diet-induced obesity by restoring IL-22-mediated colonic health J Zou, B Chassaing, V Singh, M Pellizzon, M Ricci, MD Fythe, MV Kumar, ... Cell host & microbe 23 (1), 41-53. e4, 2018 | 479 | 2018 |
Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation B Chassaing, T Van de Wiele, J De Bodt, M Marzorati, AT Gewirtz Gut 66 (8), 1414-1427, 2017 | 475 | 2017 |
Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans T Hagan, M Cortese, N Rouphael, C Boudreau, C Linde, MS Maddur, ... Cell 178 (6), 1313-1328. e13, 2019 | 455 | 2019 |
Dysregulated microbial fermentation of soluble fiber induces cholestatic liver cancer V Singh, B San Yeoh, B Chassaing, X Xiao, P Saha, RA Olvera, JD Lapek, ... Cell 175 (3), 679-694. e22, 2018 | 404 | 2018 |
Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling M Anitha, M Vijay–Kumar, SV Sitaraman, AT Gewirtz, S Srinivasan Gastroenterology 143 (4), 1006-1016. e4, 2012 | 386 | 2012 |
Microbiota‐liver axis in hepatic disease B Chassaing, L Etienne‐Mesmin, AT Gewirtz Hepatology 59 (1), 328-339, 2014 | 373 | 2014 |