Structural mechanism of ligand activation in human calcium-sensing receptor Y Geng, L Mosyak, I Kurinov, H Zuo, E Sturchler, TC Cheng, ... Elife 5, e13662, 2016 | 243 | 2016 |
Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect MJ Ortuño, ST Robinson, P Subramanyam, R Paone, Y Huang, XE Guo, ... Nature medicine 22 (10), 1170-1179, 2016 | 104 | 2016 |
Inhibition of NAPDH oxidase 2 (NOX2) prevents oxidative stress and mitochondrial abnormalities caused by saturated fat in cardiomyocytes LC Joseph, E Barca, P Subramanyam, M Komrowski, U Pajvani, ... PloS one 11 (1), e0145750, 2016 | 101 | 2016 |
Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function LC Joseph, D Kokkinaki, MC Valenti, GJ Kim, E Barca, D Tomar, ... JCI insight 2 (17), 2017 | 93 | 2017 |
Reciprocal interactions regulate targeting of calcium channel β subunits and membrane expression of α1 subunits in cultured hippocampal neurons GJ Obermair, B Schlick, V Di Biase, P Subramanyam, M Gebhart, ... Journal of biological chemistry 285 (8), 5776-5791, 2010 | 75 | 2010 |
Cardiac CaV1.2 channels require β subunits for β-adrenergic–mediated modulation but not trafficking L Yang, A Katchman, J Kushner, A Kushnir, SI Zakharov, B Chen, Z Shuja, ... The Journal of clinical investigation 129 (2), 647-658, 2019 | 63 | 2019 |
Activity and calcium regulate nuclear targeting of the calcium channel beta4b subunit in nerve and muscle cells P Subramanyam, GJ Obermair, S Baumgartner, M Gebhart, J Striessnig, ... Channels 3 (5), 343-355, 2009 | 60 | 2009 |
Ion channel engineering: perspectives and strategies P Subramanyam, HM Colecraft Journal of molecular biology 427 (1), 190-204, 2015 | 55 | 2015 |
LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms AS Aromolaran, P Subramanyam, DD Chang, WR Kobertz, HM Colecraft Cardiovascular research 104 (3), 501-511, 2014 | 53 | 2014 |
Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia LC Joseph, P Subramanyam, C Radlicz, CM Trent, V Iyer, HM Colecraft, ... Heart rhythm 13 (8), 1699-1706, 2016 | 46 | 2016 |
Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing P Subramanyam, DD Chang, K Fang, W Xie, AR Marks, HM Colecraft Proceedings of the National Academy of Sciences 110 (38), 15461-15466, 2013 | 43 | 2013 |
Dietary saturated fat promotes arrhythmia by activating NOX2 (NADPH oxidase 2) LC Joseph, UMR Avula, EY Wan, MV Reyes, KR Lakkadi, ... Circulation: Arrhythmia and Electrophysiology 12 (11), e007573, 2019 | 28 | 2019 |
Similar molecular determinants on Rem mediate two distinct modes of inhibition of CaV1.2 channels AA Puckerin, DD Chang, P Subramanyam, HM Colecraft Channels 10 (5), 379-394, 2016 | 15 | 2016 |
Correction: Inhibition of NAPDH oxidase 2 (NOX2) prevents oxidative stress and mitochondrial abnormalities caused by saturated fat in Cardiomyocytes LC Joseph, E Barca, P Subramanyam, M Komrowski, U Pajvani, ... Plos one 12 (3), e0174525, 2017 | 4 | 2017 |
N-terminal variant Asp14Asn of the human p70 S6 Kinase 1 enhances translational signaling causing different effects in developing and mature neuronal cells JP Venkatasubramani, P Subramanyam, R Pal, BK Reddy, DJ Srinivasan, ... Neurobiology of Learning and Memory 171, 107203, 2020 | 2 | 2020 |
Trafficking and Gating Mechanisms of HERG1A C-Terminus (LQTS-2) Truncation Mutations on HERG1A-HERG1B Hetero-Multimeric Channel A Puckerin, DD Chang, P Subramanyam, HM Colecraft, AS Aromolaran Biophysical Journal 108 (2), 196a, 2015 | 1 | 2015 |
Dietary Saturated Fat Promotes Arrhythmia by Activating NOX2 (NADPH Oxidase 2). LC Joseph, UMR Avula, EY Wan, MV Reyes, KR Lakkadi, ... Circulation 2020 (141), 149-154, 2020 | | 2020 |
Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes (vol 11, e0145750, 2016) LC Joseph, E Barca, P Subramanyam, M Komrowski, U Pajvani, ... PLOS ONE 12 (3), 2017 | | 2017 |
High Saturated Fat Diet Increases Ventricular Ectopy by Activating NADPH Oxidase 2. LC Joseph, P Subramanyam, HM Colecraft, JP Morrow JOURNAL OF GENERAL PHYSIOLOGY 146 (3), 8A-9A, 2015 | | 2015 |
Dissecting Roles of Distinct alpha (1C) Intracellular Domains in Functional Targeting of Ca (V) 1.2 Channels to Dyadic Junctions in Cardiomyocytes. P Subramanyam, DD Chang, HM Colecraft JOURNAL OF GENERAL PHYSIOLOGY 146 (3), 14A-15A, 2015 | | 2015 |