A unified lead-oriented synthesis of over fifty molecular scaffolds RG Doveston, P Tosatti, M Dow, DJ Foley, HY Li, AJ Campbell, D House, ... Organic & biomolecular chemistry 13 (3), 859-865, 2015 | 80 | 2015 |
Towards the systematic exploration of chemical space M Dow, M Fisher, T James, F Marchetti, A Nelson Organic & biomolecular chemistry 10 (1), 17-28, 2012 | 76 | 2012 |
Activity‐Directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists G Karageorgis, M Dow, A Aimon, S Warriner, A Nelson Angewandte Chemie 127 (46), 13742-13748, 2015 | 39 | 2015 |
Design, synthesis and decoration of molecular scaffolds for exploitation in the production of alkaloid-like libraries P Craven, A Aimon, M Dow, N Fleury-Bregeot, R Guilleux, R Morgentin, ... Bioorganic & Medicinal Chemistry 23 (11), 2629-2635, 2015 | 38 | 2015 |
Modular Synthesis of Diverse Natural Product‐Like Macrocycles: Discovery of Hits with Antimycobacterial Activity M Dow, F Marchetti, KA Abrahams, L Vaz, GS Besra, S Warriner, A Nelson Chemistry–A European Journal 23 (30), 7207-7211, 2017 | 24 | 2017 |
Single point activation of pyridines enables reductive hydroxymethylation B Marinic, HB Hepburn, A Grozavu, M Dow, TJ Donohoe Chemical Science 12 (2), 742-746, 2021 | 23 | 2021 |
Realisation of small molecule libraries based on frameworks distantly related to natural products A Aimon, G Karageorgis, J Masters, M Dow, PGE Craven, M Ohsten, ... Organic & biomolecular chemistry 16 (17), 3160-3167, 2018 | 21 | 2018 |
Translation of innovative chemistry into screening libraries: an exemplar partnership from the European Lead Factory R Morgentin, M Dow, A Aimon, G Karageorgis, T Kalliokoski, D Roche, ... Drug discovery today 23 (9), 1578-1583, 2018 | 19 | 2018 |
Evolution of the Dearomative Functionalization of Activated Quinolines and Isoquinolines: Expansion of the Electrophile Scope M Kischkewitz, B Marinic, N Kratena, Y Lai, HB Hepburn, M Dow, ... Angewandte Chemie International Edition 61 (27), e202204682, 2022 | 16 | 2022 |
Synthesis of skeletally diverse alkaloid-like molecules: exploitation of metathesis substrates assembled from triplets of building blocks SK Maurya, M Dow, S Warriner, A Nelson Beilstein Journal of Organic Chemistry 9 (1), 775-785, 2013 | 14 | 2013 |
Morphological subprofile analysis for bioactivity annotation of small molecules A Pahl, B Schölermann, P Lampe, M Rusch, M Dow, C Hedberg, ... Cell Chemical Biology 30 (7), 839-853. e7, 2023 | 12 | 2023 |
Identification of dihydroorotate dehydrogenase inhibitors using the cell painting assay B Schölermann, J Bonowski, M Grigalunas, A Burhop, Y Xie, JGF Hoock, ... ChemBioChem 23 (22), e202200475, 2022 | 11 | 2022 |
Synthetic Route Design of AZD4635, an A2AR Antagonist MM Littleson, AD Campbell, A Clarke, M Dow, G Ensor, MC Evans, ... Organic Process Research & Development 23 (7), 1407-1419, 2019 | 11 | 2019 |
Efficient Approaches for the Synthesis of Diverse α-Diazo Amides S Chow, AI Green, C Arter, S Liver, A Leggott, L Trask, G Karageorgis, ... Synthesis 52 (11), 1695-1706, 2020 | 7 | 2020 |
Diversity‐Oriented Synthesis of Natural Product–Like Libraries M Dow, F Marchetti, A Nelson Diversity‐Oriented Synthesis: Basics and Applications in Organic Synthesis …, 2013 | 5 | 2013 |
Synthesis of spirocyclic 1, 2-diamines by dearomatising intramolecular diamination of phenols A Aimon, MJ Dow, AR Hanby, EA Okolo, CM Pask, A Nelson, SP Marsden Chemical Communications 59 (5), 607-610, 2023 | 2 | 2023 |
Frontispiece: Activity‐Directed Synthesis with Intermolecular Reactions: Development of a Fragment into a Range of Androgen Receptor Agonists G Karageorgis, M Dow, A Aimon, S Warriner, A Nelson Angewandte Chemie International Edition 46 (54), n/a-n/a, 2015 | | 2015 |
Practical Methods for Biocatalysis and Biotransformations 2 http://onlinelibrary.wiley.com/book/10.1002/9781119943426, 203-229, 2013 | | 2013 |
Development of methods for the synthesis of natural product-like macrocycles MJL Dow University of Leeds, 2012 | | 2012 |