A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1 ON Ozes, H Akca, LD Mayo, JA Gustin, T Maehama, JE Dixon, DB Donner Proceedings of the National Academy of Sciences 98 (8), 4640-4645, 2001 | 516 | 2001 |
Cell type-specific expression of the IκB kinases determines the significance of phosphatidylinositol 3-kinase/Akt signaling to NF-κB activation JA Gustin, ON Ozes, H Akca, R Pincheira, LD Mayo, Q Li, JR Guzman, ... Journal of Biological Chemistry 279 (3), 1615-1620, 2004 | 267 | 2004 |
Invasiveness and anchorage independent growth ability augmented by PTEN inactivation through the PI3K/AKT/NFkB pathway in lung cancer cells H Akca, A Demiray, O Tokgun, J Yokota Lung cancer 73 (3), 302-309, 2011 | 103 | 2011 |
Multidrug resistance-associated protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and Buthionine sulfoximine I Akan, S Akan, H Akca, B Savas, T Ozben Cancer cell international 5, 1-9, 2005 | 93 | 2005 |
Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cells H Akca, M Tani, T Hishida, S Matsumoto, J Yokota Lung cancer 54 (1), 25-33, 2006 | 85 | 2006 |
Zinc oxide nanoparticles: Genotoxicity, interactions with UV-light and cell-transforming potential E Demir, H Akça, B Kaya, D Burgucu, O Tokgün, F Turna, S Aksakal, ... Journal of hazardous materials 264, 420-429, 2014 | 83 | 2014 |
Genotoxic and cell-transforming effects of titanium dioxide nanoparticles E Demir, H Akça, F Turna, S Aksakal, D Burgucu, B Kaya, O Tokgün, ... Environmental Research 136, 300-308, 2015 | 78 | 2015 |
Utility of serum DNA and pyrosequencing for the detection of EGFR mutations in non-small cell lung cancer H Akca, A Demiray, A Yaren, F Bir, A Koseler, R Iwakawa, G Bagci, ... Cancer genetics 206 (3), 73-80, 2013 | 58 | 2013 |
Tumour suppressor PTEN enhanced enzyme activity of GPx, SOD and catalase by suppression of PI3K/AKT pathway in non-small cell lung cancer cell lines H Akca, A Demiray, M Aslan, I Acikbas, O Tokgun Journal of Enzyme Inhibition and Medicinal Chemistry 28 (3), 539-544, 2013 | 47 | 2013 |
miR-181b-5p, miR-195-5p and miR-301a-3p are related with treatment resistance in schizophrenia H Alacam, S Akgun, H Akca, O Ozturk, BB Kabukcu, H Herken Psychiatry research 245, 200-206, 2016 | 40 | 2016 |
Convolvulus galaticus, Crocus antalyensis, and Lilium candidum Extracts Show Their Antitumor Activity Through Induction of p53-Mediated Apoptosis on Human … O Tokgun, H Akca, R Mammadov, C Aykurt, G Deniz Journal of medicinal food 15 (11), 1000-1005, 2012 | 39 | 2012 |
Melatonin can suppress the cytotoxic effects of chlorpyrifos on human hepG2 cell lines F Gultekin, S Patat, H Akça, M Akdogan, I Altuntas Human & experimental toxicology 25 (2), 47-55, 2006 | 37 | 2006 |
N‐acetylcysteine enhances multidrug resistance‐associated protein 1 mediated doxorubicin resistance I Akan, S Akan, H Akça, B Savas, T Ozben European journal of clinical investigation 34 (10), 683-689, 2004 | 35 | 2004 |
MYC-driven regulation of long non-coding RNA profiles in breast cancer cells PE Tokgun, O Tokgun, S Kurt, AG Tomatir, H Akca Gene 714, 143955, 2019 | 29 | 2019 |
Cyclamen exerts cytotoxicity in solid tumor cell lines: a step toward new anticancer agents? M Yildiz, H Bozcuk, O Tokgün, ER Karagur, O Akyurt, H Akca Asian Pacific journal of cancer prevention, 2013 | 27 | 2013 |
Downregulation of SATB2 is critical for induction of epithelial-to-mesenchymal transition and invasion of NSCLC cells H Kucuksayan, ON Ozes, H Akca Lung Cancer 98, 122-129, 2016 | 23 | 2016 |
The protective effect of docosahexaenoic acid on the bilirubin neurotoxicity C Becerir, İ Kılıç, Ö Şahin, Ö Özdemir, O Tokgün, B Özdemir, H Akca Journal of Enzyme Inhibition and Medicinal Chemistry 28 (4), 801-807, 2013 | 23 | 2013 |
Caffeine prevents bilirubin-induced cytotoxicity in cultured newborn rat astrocytes M Deliktaş, H Ergin, A Demiray, H Akça, ÖMA Özdemir, MB Özdemir The Journal of Maternal-Fetal & Neonatal Medicine 32 (11), 1813-1819, 2019 | 21 | 2019 |
lncRNAs as potential targets in small cell lung cancer: MYC-dependent regulation O Tokgun, PE Tokgun, K Inci, H Akca Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2020 | 20 | 2020 |
Silica nanoparticles can induce apoptosis via dead receptor and caspase 8 pathway on A549 cells O Tokgun, A Demiray, B Kaya, ER Karagür, E Demir, E Burunkaya, ... Adv Food Sci 37, 65-70, 2015 | 19 | 2015 |