Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19 RS Thwaites, A Sanchez Sevilla Uruchurtu, MK Siggins, F Liew, ... Science immunology 6 (57), eabg9873, 2021 | 176 | 2021 |
Frequency of epitope-specific naive CD4+ T cells correlates with immunodominance in the human memory repertoire WW Kwok, V Tan, L Gillette, CT Littell, MA Soltis, RB LaFond, J Yang, ... The Journal of Immunology 188 (6), 2537-2544, 2012 | 126 | 2012 |
Induction and subversion of human protective immunity: contrasting influenza and respiratory syncytial virus S Ascough, S Paterson, C Chiu Frontiers in Immunology 9, 344992, 2018 | 70 | 2018 |
Natural exposure to cutaneous anthrax gives long-lasting T cell immunity encompassing infection-specific epitopes RJ Ingram, G Metan, B Maillere, M Doganay, Y Ozkul, LU Kim, L Baillie, ... The Journal of Immunology 184 (7), 3814-3821, 2010 | 63 | 2010 |
Epitope-specific airway-resident CD4+ T cell dynamics during experimental human RSV infection A Guvenel, A Jozwik, S Ascough, SK Ung, S Paterson, M Kalyan, ... The Journal of clinical investigation 130 (1), 523-538, 2020 | 55 | 2020 |
Th1 not Th17 cells drive spontaneous MS-like disease despite a functional regulatory T cell response DE Lowther, DL Chong, S Ascough, A Ettorre, RJ Ingram, RJ Boyton, ... Acta neuropathologica 126, 501-515, 2013 | 44 | 2013 |
HLA-DQB1* 0602 determines disease susceptibility in a new “humanized” multiple sclerosis model in HLA-DR15 (DRB1* 1501; DQB1* 0602) transgenic mice N Kaushansky, DM Altmann, S Ascough, CS David, H Lassmann, ... The Journal of Immunology 183 (5), 3531-3541, 2009 | 32 | 2009 |
Local and systemic immunity against respiratory syncytial virus induced by a novel intranasal vaccine. A randomized, double-blind, placebo-controlled clinical trial S Ascough, I Vlachantoni, M Kalyan, BJ Haijema, S Wallin-Weber, ... American journal of respiratory and critical care medicine 200 (4), 481-492, 2019 | 31 | 2019 |
Host genetics determine susceptibility to avian influenza infection and transmission dynamics R Ruiz-Hernandez, W Mwangi, M Peroval, JR Sadeyen, S Ascough, ... Scientific Reports 6 (1), 26787, 2016 | 31 | 2016 |
Anthrax Lethal Factor as an Immune Target in Humans and Transgenic Mice and the Impact of HLA Polymorphism on CD4+ T Cell Immunity S Ascough, RJ Ingram, KK Chu, CJ Reynolds, JA Musson, M Doganay, ... PLoS pathogens 10 (5), e1004085, 2014 | 30 | 2014 |
Repertoire of HLA-DR1-Restricted CD4 T-Cell Responses to Capsular Caf1 Antigen of Yersinia pestis in Human Leukocyte Antigen Transgenic Mice JA Musson, R Ingram, G Durand, S Ascough, EL Waters, MG Hartley, ... Infection and Immunity 78 (10), 4356-4362, 2010 | 24 | 2010 |
Innate-like Gene Expression of Lung-Resident Memory CD8+ T Cells during Experimental Human Influenza: A Clinical Study S Paterson, S Kar, SK Ung, Z Gardener, E Bergstrom, S Ascough, ... American journal of respiratory and critical care medicine 204 (7), 826-841, 2021 | 18 | 2021 |
Anthrax in injecting drug users: the need for increased vigilance in the clinic S Ascough, DM Altmann Expert review of anti-infective therapy 13 (6), 681-684, 2015 | 18 | 2015 |
Exposure to anthrax toxin alters human leucocyte expression of anthrax toxin receptor 1 RJ Ingram, A Harris, S Ascough, G Metan, M Doganay, L Ballie, ... Clinical & Experimental Immunology 173 (1), 84-91, 2013 | 18 | 2013 |
CD4+ T Cells Targeting Dominant and Cryptic Epitopes from Bacillus anthracis Lethal Factor S Ascough, RJ Ingram, KKY Chu, JA Musson, SJ Moore, T Gallagher, ... Frontiers in microbiology 6, 1506, 2016 | 16 | 2016 |
Injectional anthrax infection due to heroin use induces strong immunological memory S Ascough, RJ Ingram, A Abarra, AJ Holmes, B Maillere, DM Altmann, ... Journal of Infection 68 (2), 200-203, 2014 | 15 | 2014 |
Anthrax lethal toxin and the induction of CD4 T cell immunity S Ascough, RJ Ingram, DM Altmann Toxins 4 (10), 878-899, 2012 | 15 | 2012 |
Natural cutaneous anthrax infection, but not vaccination, induces a CD4+ T cell response involving diverse cytokines RJ Ingram, S Ascough, CJ Reynolds, G Metan, M Doganay, L Baillie, ... Cell & bioscience 5, 1-6, 2015 | 12 | 2015 |
An Epitope of Bacillus anthracis Protective Antigen That Is Cryptic in Rabbits May Be Immunodominant in Humans RJ Ingram, KK Chu, G Metan, B Maillere, M Doganay, Y Ozkul, H Dyson, ... Infection and immunity 78 (5), 2353-2354, 2010 | 12 | 2010 |
Divergent age-related humoral correlates of protection against respiratory syncytial virus infection in older and young adults: a pilot, controlled, human infection challenge model S Ascough, P Dayananda, M Kalyan, SU Kuong, Z Gardener, E Bergstrom, ... The Lancet Healthy Longevity 3 (6), e405-e416, 2022 | 11 | 2022 |