De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy G Barcia, MR Fleming, A Deligniere, VR Gazula, MR Brown, M Langouet, ... Nature genetics 44 (11), 1255-1259, 2012 | 504 | 2012 |
TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices M Zhou, G Xu, M Xie, X Zhang, GP Schools, L Ma, HK Kimelberg, H Chen Journal of Neuroscience 29 (26), 8551-8564, 2009 | 204 | 2009 |
Charybdotoxin binding in the IKs pore demonstrates two MinK subunits in each channel complex H Chen, LA Kim, S Rajan, S Xu, SAN Goldstein Neuron 40 (1), 15-23, 2003 | 176 | 2003 |
Modulation of cloned skeletal muscle sodium channels by the scorpion toxins Lqh II, Lqh III, and LqhαIT H Chen, D Gordon, SH Heinemann PfluÈgers Archiv 439, 423-432, 2000 | 92 | 2000 |
The N-terminal domain of Slack determines the formation and trafficking of Slick/Slack heteromeric sodium-activated potassium channels H Chen, J Kronengold, Y Yan, VR Gazula, MR Brown, L Ma, G Ferreira, ... Journal of Neuroscience 29 (17), 5654-5665, 2009 | 86 | 2009 |
TWIK-1 two-pore domain potassium channels change ion selectivity and conduct inward leak sodium currents in hypokalemia L Ma, X Zhang, H Chen Science signaling 4 (176), ra37-ra37, 2011 | 83 | 2011 |
A δ-conotoxin from Conus ermineus venom inhibits inactivation in vertebrate neuronal Na+ channels but not in skeletal and cardiac muscles J Barbier, H Lamthanh, F Le Gall, P Favreau, E Benoit, H Chen, N Gilles, ... Journal of Biological Chemistry 279 (6), 4680-4685, 2004 | 83 | 2004 |
Localization of Kv1. 3 channels in presynaptic terminals of brainstem auditory neurons VR Gazula, JG Strumbos, X Mei, H Chen, C Rahner, LK Kaczmarek Journal of Comparative Neurology 518 (16), 3205-3220, 2010 | 71 | 2010 |
Interaction of scorpion α-toxins with cardiac sodium channels: binding properties and enhancement of slow inactivation H Chen, SH Heinemann The Journal of general physiology 117 (6), 505-518, 2001 | 64 | 2001 |
Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidification L Ma, X Zhang, M Zhou, H Chen Journal of Biological Chemistry 287 (44), 37145-37153, 2012 | 63 | 2012 |
Functional analysis of a novel potassium channel (KCNA1) mutation in hereditary myokymia H Chen, C von Hehn, LK Kaczmarek, LR Ment, BR Pober, FM Hisama Neurogenetics 8, 131-135, 2007 | 54 | 2007 |
Scorpion α and α‐like toxins differentially interact with sodium channels in mammalian CNS and periphery N Gilles, H Chen, H Wilson, F Le Gall, G Montoya, J Molgo, R SchoÈnherr, ... European Journal of Neuroscience 12 (8), 2823-2832, 2000 | 47 | 2000 |
Genetic deletion of TREK-1 or TWIK-1/TREK-1 potassium channels does not alter the basic electrophysiological properties of mature hippocampal astrocytes in situ Y Du, CM Kiyoshi, Q Wang, W Wang, B Ma, CC Alford, S Zhong, Q Wan, ... Frontiers in cellular neuroscience 10, 13, 2016 | 45 | 2016 |
The contribution of TWIK-1 channels to astrocyte K+ current is limited by retention in intracellular compartments W Wang, A Putra, GP Schools, B Ma, H Chen, LK Kaczmarek, J Barhanin, ... Frontiers in cellular neuroscience 7, 246, 2013 | 43 | 2013 |
Pore-and state-dependent cadmium block of IKs channels formed with MinK-55C and wild-type KCNQ1 subunits H Chen, F Sesti, SAN Goldstein Biophysical journal 84 (6), 3679-3689, 2003 | 39 | 2003 |
Effect of depolarization on binding kinetics of scorpion α-toxin highlights conformational changes of rat brain sodium channels N Gilles, E Leipold, H Chen, SH Heinemann, D Gordon Biochemistry 40 (48), 14576-14584, 2001 | 39 | 2001 |
Altered and dynamic ion selectivity of K+ channels in cell development and excitability H Chen, FC Chatelain, F Lesage Trends in pharmacological sciences 35 (9), 461-469, 2014 | 36 | 2014 |
Identification of functionally relevant residues of the rat ileal apical sodium-dependent bile acid cotransporter AQ Sun, N Balasubramaniyan, H Chen, M Shahid, FJ Suchy Journal of Biological Chemistry 281 (24), 16410-16418, 2006 | 32 | 2006 |
Pathogenic mechanism of a catecholaminergic polymorphic ventricular tachycardia causing-mutation in cardiac calcium release channel RyR2 J Xiong, X Liu, Y Gong, P Zhang, S Qiang, Q Zhao, R Guo, Y Qian, ... Journal of Molecular and Cellular Cardiology 117, 26-35, 2018 | 27 | 2018 |
Silent TWIK-1 potassium channels conduct monovalent cation currents L Ma, YP Xie, M Zhou, H Chen Biophysical journal 102 (8), L34-L36, 2012 | 22 | 2012 |