| Activation of histone deacetylase-6 induces contractile dysfunction through derailment of α-tubulin proteostasis in experimental and human atrial fibrillation D Zhang, CT Wu, XY Qi, RAM Meijering, F Hoogstra-Berends, ... Circulation 129 (3), 346-358, 2014 | 167 | 2014 |
| DNA damage-induced PARP1 activation confers cardiomyocyte dysfunction through NAD+ depletion in experimental atrial fibrillation D Zhang, X Hu, J Li, J Liu, L Baks-te Bulte, M Wiersma, NA Malik, ... Nature communications 10 (1), 1307, 2019 | 107 | 2019 |
| Endoplasmic reticulum stress is associated with autophagy and cardiomyocyte remodeling in experimental and human atrial fibrillation M Wiersma, RAM Meijering, XY Qi, D Zhang, T Liu, F Hoogstra‐Berends, ... Journal of the American Heart Association 6 (10), e006458, 2017 | 104 | 2017 |
| Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation D Zhang, L Ke, K Mackovicova, JJL Van Der Want, OCM Sibon, ... Journal of molecular and cellular cardiology 51 (3), 381-389, 2011 | 90 | 2011 |
| Mitochondrial dysfunction underlies cardiomyocyte remodeling in experimental and clinical atrial fibrillation M Wiersma, DMS van Marion, RCI Wüst, RH Houtkooper, D Zhang, ... Cells 8 (10), 1202, 2019 | 71 | 2019 |
| Hydroximic acid derivatives: pleiotropic HSP co-inducers restoring homeostasis and robustness T Crul, N Toth, S Piotto, P Literati-Nagy, K Tory, P Haldimann, B Kalmar, ... Current Pharmaceutical Design 19 (3), 309-346, 2013 | 66 | 2013 |
| Keeping up the balance: role of HDACs in cardiac proteostasis and therapeutic implications for atrial fibrillation D Zhang, X Hu, RH Henning, BJJM Brundel Cardiovascular research 109 (4), 519-526, 2016 | 47 | 2016 |
| Role of autophagy in proteostasis: friend and foe in cardiac diseases J Li, D Zhang, M Wiersma, BJJM Brundel Cells 7 (12), 279, 2018 | 45 | 2018 |
| Imbalance of ER and mitochondria interactions: prelude to cardiac ageing and disease? J Li, D Zhang, BJJM Brundel, M Wiersma Cells 8 (12), 1617, 2019 | 41 | 2019 |
| Porcine induced pluripotent stem cells may bridge the gap between mouse and human iPS MA Esteban, M Peng, Z Deli, J Cai, J Yang, J Xu, L Lai, D Pei IUBMB life 62 (4), 277-282, 2010 | 36 | 2010 |
| Loss of proteostatic control as a substrate for atrial fibrillation: a novel target for upstream therapy by heat shock proteins RAM Meijering, D Zhang, F Hoogstra-Berends, RH Henning, ... Frontiers in Physiology 3, 36, 2012 | 34 | 2012 |
| Cell-free circulating mitochondrial DNA: a potential blood-based marker for atrial fibrillation M Wiersma, DMS van Marion, EJ Bouman, J Li, D Zhang, KS Ramos, ... Cells 9 (5), 1159, 2020 | 33 | 2020 |
| The protective role of small heat shock proteins in cardiac diseases: key role in atrial fibrillation X Hu, DMS Van Marion, M Wiersma, D Zhang, BJJM Brundel Cell Stress and Chaperones 22 (4), 665-674, 2017 | 33 | 2017 |
| Role of oxidative DNA damage and repair in atrial fibrillation and ischemic heart disease L Hu, Z Wang, C Carmone, J Keijer, D Zhang International journal of molecular sciences 22 (8), 3838, 2021 | 29 | 2021 |
| Converse role of class I and class IIa HDACs in the progression of atrial fibrillation D Zhang, X Hu, J Li, F Hoogstra-Berends, Q Zhuang, MA Esteban, ... Journal of molecular and cellular cardiology 125, 39-49, 2018 | 29 | 2018 |
| Rice MAPK phosphatase IBR5 negatively regulates drought stress tolerance in transgenic Nicotiana tabacum Y Li, D Feng, D Zhang, J Su, Y Zhang, Z Li, P Mu, B Liu, H Wang, J Wang Plant science 188, 10-18, 2012 | 28 | 2012 |
| Blood-based 8-hydroxy-2′-deoxyguanosine level: a potential diagnostic biomarker for atrial fibrillation J Li, D Zhang, KS Ramos, L Baks, M Wiersma, EAH Lanters, AJJC Bogers, ... Heart Rhythm 18 (2), 271-277, 2021 | 21 | 2021 |
| Heat shock protein inducer GGA*-59 reverses contractile and structural remodeling via restoration of the microtubule network in experimental Atrial Fibrillation X Hu, J Li, DMS van Marion, D Zhang, BJJM Brundel Journal of molecular and cellular cardiology 134, 86-97, 2019 | 20 | 2019 |
| Screening of novel HSP-inducing compounds to conserve cardiomyocyte function in experimental atrial fibrillation DM Van Marion, X Hu, D Zhang, F Hoogstra-Berends, JPG Seerden, ... Drug Design, Development and Therapy, 345-364, 2019 | 20 | 2019 |
| Role of HDACs in cardiac electropathology: therapeutic implications for atrial fibrillation BJJM Brundel, J Li, D Zhang Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (3), 118459, 2020 | 19 | 2020 |
Stanley NattelProfessor of Medicine, Université de MontréalVerified email at icm-mhi.org
