Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I MY El-Mir, V Nogueira, E Fontaine, N Avéret, M Rigoulet, X Leverve Journal of Biological Chemistry 275 (1), 223-228, 2000 | 1667 | 2000 |
Regulation of the permeability transition pore in skeletal muscle mitochondria: modulation by electron flow through the respiratory chain complex I E Fontaine, O Eriksson, F Ichas, P Bernardi Journal of Biological Chemistry 273 (20), 12662-12668, 1998 | 415 | 1998 |
Gut microbiota richness promotes its stability upon increased dietary fibre intake in healthy adults J Tap, JP Furet, M Bensaada, C Philippe, H Roth, S Rabot, O Lakhdari, ... Environmental microbiology 17 (12), 4954-4964, 2015 | 365 | 2015 |
The ROS production induced by a reverse-electron flux at respiratory-chain complex 1 is hampered by metformin C Batandier, B Guigas, D Detaille, M El-Mir, E Fontaine, M Rigoulet, ... Journal of bioenergetics and biomembranes 38, 33-42, 2006 | 349 | 2006 |
Metformin prevents high-glucose–induced endothelial cell death through a mitochondrial permeability transition-dependent process D Detaille, B Guigas, C Chauvin, C Batandier, E Fontaine, ... Diabetes 54 (7), 2179-2187, 2005 | 329 | 2005 |
A ubiquinone-binding site regulates the mitochondrial permeability transition pore E Fontaine, F Ichas, P Bernardi Journal of Biological Chemistry 273 (40), 25734-25740, 1998 | 323 | 1998 |
Opening of the mitochondrial permeability transition pore induces reactive oxygen species production at the level of the respiratory chain complex I C Batandier, X Leverve, E Fontaine Journal of Biological Chemistry 279 (17), 17197-17204, 2004 | 315 | 2004 |
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons MY El-Mir, D Detaille, G R-Villanueva, M Delgado-Esteban, B Guigas, ... Journal of Molecular Neuroscience 34, 77-87, 2008 | 281 | 2008 |
Bupivacaine myotoxicity is mediated by mitochondria W Irwin, E Fontaine, L Agnolucci, D Penzo, R Betto, S Bortolotto, ... Journal of Biological Chemistry 277 (14), 12221-12227, 2002 | 228 | 2002 |
Determination of mitochondrial reactive oxygen species: methodological aspects C Batandier, E Fontaine, C Kériel, XM Leverve Journal of cellular and molecular medicine 6 (2), 175-187, 2002 | 220 | 2002 |
Metformin-induced mitochondrial complex I inhibition: facts, uncertainties, and consequences E Fontaine Frontiers in endocrinology 9, 390473, 2018 | 212 | 2018 |
The mitochondrial permeability transition P Bernardi, R Colonna, P Costantini, O Eriksson, E Fontaine, F Ichas, ... Biofactors 8 (3‐4), 273-281, 1998 | 212 | 1998 |
Mitochondrial metabolism and type-2 diabetes: a specific target of metformin XM Leverve, B Guigas, D Detaille, C Batandier, EA Koceir, C Chauvin, ... Diabetes & metabolism 29 (4), 6S88-6S94, 2003 | 189 | 2003 |
Progress on the mitochondrial permeability transition pore: regulation by complex I and ubiquinone analogs E Fontaine, P Bernardi Journal of bioenergetics and biomembranes 31, 335-345, 1999 | 185 | 1999 |
Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study B Guigas, D Detaille, C Chauvin, C Batandier, F De Oliveira, E Fontaine, ... Biochemical journal 382 (3), 877-884, 2004 | 183 | 2004 |
Three classes of ubiquinone analogs regulate the mitochondrial permeability transition pore through a common site L Walter, V Nogueira, X Leverve, MP Heitz, P Bernardi, E Fontaine Journal of Biological Chemistry 275 (38), 29521-29527, 2000 | 180 | 2000 |
Rotenone inhibits the mitochondrial permeability transition-induced cell death in U937 and KB cells C Chauvin, F De Oliveira, X Ronot, M Mousseau, X Leverve, E Fontaine Journal of Biological Chemistry 276 (44), 41394-41398, 2001 | 173 | 2001 |
Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice model G Vial, MA Chauvin, N Bendridi, A Durand, E Meugnier, AM Madec, ... Diabetes 64 (6), 2254-2264, 2015 | 159 | 2015 |
Study of regulation of mitochondrial respiration in vivo: an analysis of influence of ADP diffusion and possible role of cytoskeleton L Kay, Z Li, M Mericskay, J Olivares, L Tranqui, E Fontaine, T Tiivel, P Sikk, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1322 (1), 41-59, 1997 | 153 | 1997 |
Nitric oxide increases oxidative phosphorylation efficiency P Clerc, M Rigoulet, X Leverve, E Fontaine Journal of bioenergetics and biomembranes 39, 158-166, 2007 | 139 | 2007 |