| A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death J Ham, C Babij, J Whitfield, CM Pfarr, D Lallemand, M Yaniv, LL Rubin Neuron 14 (5), 927-939, 1995 | 1022 | 1995 |
| Modelling Myc inhibition as a cancer therapy L Soucek, J Whitfield, CP Martins, AJ Finch, DJ Murphy, NM Sodir, ... Nature 455 (7213), 679-683, 2008 | 948 | 2008 |
| Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release J Whitfield, SJ Neame, L Paquet, O Bernard, J Ham Neuron 29 (3), 629-643, 2001 | 742 | 2001 |
| Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons A Eilers, J Whitfield, C Babij, LL Rubin, J Ham Journal of Neuroscience 18 (5), 1713-1724, 1998 | 372 | 1998 |
| Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice L Soucek, JR Whitfield, NM Sodir, D Massó-Vallés, E Serrano, ... Genes & development 27 (5), 504-513, 2013 | 347 | 2013 |
| Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ... Carcinogenesis 36 (Suppl_1), S254-S296, 2015 | 338 | 2015 |
| Strategies to inhibit Myc and their clinical applicability JR Whitfield, ME Beaulieu, L Soucek Frontiers in cell and developmental biology 5, 10, 2017 | 309 | 2017 |
| c-Jun and the transcriptional control of neuronal apoptosis J Ham, A Eilers, J Whitfield, SJ Neame, B Shah Biochemical pharmacology 60 (8), 1015-1021, 2000 | 284 | 2000 |
| Bax promotes neuronal cell death and is downregulated during the development of the nervous system K Vekrellis, MJ McCarthy, A Watson, J Whitfield, LL Rubin, J Ham Development 124 (6), 1239-1249, 1997 | 273 | 1997 |
| Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis D Annibali, JR Whitfield, E Favuzzi, T Jauset, E Serrano, I Cuartas, ... Nature communications 5 (1), 4632, 2014 | 204 | 2014 |
| Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy ME Beaulieu, T Jauset, D Massó-Vallés, S Martínez-Martín, P Rahl, ... Science translational medicine 11 (484), eaar5012, 2019 | 189 | 2019 |
| Assembly of GABAA receptors composed of α1 and β2 subunits in both cultured neurons and fibroblasts GH Gorrie, Y Vallis, A Stephenson, J Whitfield, B Browning, TG Smart, ... Journal of Neuroscience 17 (17), 6587-6596, 1997 | 165 | 1997 |
| Direct inhibition of c‐Jun N‐terminal kinase in sympathetic neurones prevents c‐jun promoter activation and NGF withdrawal‐induced death A Eilers, J Whitfield, B Shah, C Spadoni, H Desmond, J Ham Journal of neurochemistry 76 (5), 1439-1454, 2001 | 148 | 2001 |
| Transforming growth factor β (TGFβ) mediates Schwann cell death in vitro and in vivo: examination of c-Jun activation, interactions with survival signals, and the relationship … DB Parkinson, Z Dong, H Bunting, J Whitfield, C Meier, H Marie, R Mirsky, ... Journal of Neuroscience 21 (21), 8572-8585, 2001 | 137 | 2001 |
| The effect of environmental chemicals on the tumor microenvironment SC Casey, M Vaccari, F Al-Mulla, R Al-Temaimi, A Amedei, ... Carcinogenesis 36 (Suppl_1), S160-S183, 2015 | 128 | 2015 |
| Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma D Massó-Vallés, T Jauset, E Serrano, NM Sodir, K Pedersen, NI Affara, ... Cancer research 75 (8), 1675-1681, 2015 | 117 | 2015 |
| Tumor microenvironment: becoming sick of Myc JR Whitfield, L Soucek Cellular and Molecular Life Sciences 69, 931-934, 2012 | 90 | 2012 |
| Specific requirement for Bax, not Bak, in Myc-induced apoptosis and tumor suppression in vivo TB Dansen, J Whitfield, F Rostker, L Brown-Swigart, GI Evan Journal of biological chemistry 281 (16), 10890-10895, 2006 | 84 | 2006 |
| The neuroprotective action of JNK3 inhibitors based on the 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole scaffold PP Graczyk, A Khan, GS Bhatia, V Palmer, D Medland, H Numata, ... Bioorganic & medicinal chemistry letters 15 (21), 4666-4670, 2005 | 67 | 2005 |
| The long journey to bring a Myc inhibitor to the clinic JR Whitfield, L Soucek Journal of Cell Biology 220 (8), e202103090, 2021 | 59 | 2021 |
lsoucekPrincipal Investigator, Vall d'Hebron Institute of Oncologyvhio.net üzerinde doğrulanmış e-posta adresine sahip
